Evolution of a bitter taste receptor gene cluster in a New World sparrow.

Abstract:

:Bitter taste perception likely evolved as a protective mechanism against the ingestion of harmful compounds in food. The evolution of the taste receptor type 2 (TAS2R) gene family, which encodes the chemoreceptors that are directly responsible for the detection of bitter compounds, has therefore been of considerable interest. Though TAS2R repertoires have been characterized for a number of species, to date the complement of TAS2Rs from just one bird, the chicken, which had a notably small number of TAS2Rs, has been established. Here, we used targeted mapping and genomic sequencing in the white-throated sparrow (Zonotrichia albicollis) and sample sequencing in other closely related birds to reconstruct the history of a TAS2R gene cluster physically linked to the break points of an evolutionary chromosomal rearrangement. In the white-throated sparrow, this TAS2R cluster encodes up to 18 functional bitter taste receptors and likely underwent a large expansion that predates and/or coincides with the radiation of the Emberizinae subfamily into the New World. In addition to signatures of gene birth-and-death evolution within this cluster, estimates of Ka/Ks for the songbird TAS2Rs were similar to those previously observed in mammals, including humans. Finally, comparison of the complete genomic sequence of the cluster from two common haplotypes in the white-throated sparrow revealed a number of nonsynonymous variants and differences in functional gene content within this species. These results suggest that interspecies and intraspecies genetic variability does exist in avian TAS2Rs and that these differences could contribute to variation in bitter taste perception in birds.

journal_name

Genome Biol Evol

authors

Davis JK,Lowman JJ,Thomas PJ,ten Hallers BF,Koriabine M,Huynh LY,Maney DL,de Jong PJ,Martin CL,NISC Comparative Sequencing Program.,Thomas JW

doi

10.1093/gbe/evq027

subject

Has Abstract

pub_date

2010-07-12 00:00:00

pages

358-70

issn

1759-6653

pii

evq027

journal_volume

2

pub_type

杂志文章
  • Transcriptional Interference Promotes Rapid Expression Divergence of Drosophila Nested Genes.

    abstract::Nested genes are the most common form of protein-coding overlap in eukaryotic genomes. Previous studies have shown that nested genes accumulate rapidly over evolutionary time, typically via the insertion of short young duplicate genes into long introns. However, the evolutionary relationship between nested genes remai...

    journal_title:Genome biology and evolution

    pub_type: 信件

    doi:10.1093/gbe/evw237

    authors: Assis R

    更新日期:2016-10-23 00:00:00

  • Metabolic Determinants of Enzyme Evolution in a Genome-Scale Bacterial Metabolic Network.

    abstract::Different genes and proteins evolve at very different rates. To identify the factors that explain these differences is an important aspect of research in molecular evolution. One such factor is the role a protein plays in a large molecular network. Here, we analyze the evolutionary rates of enzyme-coding genes in the ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy234

    authors: Aguilar-Rodríguez J,Wagner A

    更新日期:2018-11-01 00:00:00

  • Whole Genome Incorporation and Epigenetic Stability in a Newly Synthetic Allopolyploid of Gynogenetic Gibel Carp.

    abstract::Allopolyploidization plays an important role in speciation, and some natural or synthetic allopolyploid fishes have been extensively applied to aquaculture. Although genetic and epigenetic inheritance and variation associated with plant allopolyploids have been well documented, the relative research in allopolyploid a...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy165

    authors: Shao GM,Li XY,Wang Y,Wang ZW,Li Z,Zhang XJ,Zhou L,Gui JF

    更新日期:2018-09-01 00:00:00

  • High Levels of Copy Number Variation of Ampliconic Genes across Major Human Y Haplogroups.

    abstract::Because of its highly repetitive nature, the human male-specific Y chromosome remains understudied. It is important to investigate variation on the Y chromosome to understand its evolution and contribution to phenotypic variation, including infertility. Approximately 20% of the human Y chromosome consists of ampliconi...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy086

    authors: Ye D,Zaidi AA,Tomaszkiewicz M,Anthony K,Liebowitz C,DeGiorgio M,Shriver MD,Makova KD

    更新日期:2018-05-01 00:00:00

  • Phylogenomics and evolutionary dynamics of the family Actinomycetaceae.

    abstract::The family Actinomycetaceae comprises several important pathogens that impose serious threat to human health and cause substantial infections of economically important animals. However, the phylogeny and evolutionary dynamic of this family are poorly characterized. Here, we provide detailed description of the genome c...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu211

    authors: Zhao K,Li W,Kang C,Du L,Huang T,Zhang X,Wu M,Yue B

    更新日期:2014-09-22 00:00:00

  • Nonreplicative RNA Recombination of an Animal Plus-Strand RNA Virus in the Absence of Efficient Translation of Viral Proteins.

    abstract::RNA recombination is a major driving force for the evolution of RNA viruses and is significantly implicated in the adaptation of viruses to new hosts, changes of virulence, as well as in the emergence of new viruses including drug-resistant and escape mutants. However, the molecular details of recombination in animal ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx046

    authors: Kleine Büning M,Meyer D,Austermann-Busch S,Roman-Sosa G,Rümenapf T,Becher P

    更新日期:2017-04-01 00:00:00

  • Ancient Duplications Have Led to Functional Divergence of Vitellogenin-Like Genes Potentially Involved in Inflammation and Oxidative Stress in Honey Bees.

    abstract::Protection against inflammation and oxidative stress is key in slowing down aging processes. The honey bee (Apis mellifera) shows flexible aging patterns linked to the social role of individual bees. One molecular factor associated with honey bee aging regulation is vitellogenin, a lipoglycophosphoprotein with anti-in...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw014

    authors: Salmela H,Stark T,Stucki D,Fuchs S,Freitak D,Dey A,Kent CF,Zayed A,Dhaygude K,Hokkanen H,Sundström L

    更新日期:2016-03-09 00:00:00

  • The Effect of Population Bottleneck Size and Selective Regime on Genetic Diversity and Evolvability in Bacteria.

    abstract::Population bottlenecks leading to a drastic reduction of the population size are common in the evolutionary dynamics of natural populations; their occurrence is known to have implications for genome evolution due to genetic drift, the consequent reduction in genetic diversity, and the rate of adaptation. Nevertheless,...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz243

    authors: Wein T,Dagan T

    更新日期:2019-11-01 00:00:00

  • Organellar Genomes of White Spruce (Picea glauca): Assembly and Annotation.

    abstract::The genome sequences of the plastid and mitochondrion of white spruce (Picea glauca) were assembled from whole-genome shotgun sequencing data using ABySS. The sequencing data contained reads from both the nuclear and organellar genomes, and reads of the organellar genomes were abundant in the data as each cell harbors...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv244

    authors: Jackman SD,Warren RL,Gibb EA,Vandervalk BP,Mohamadi H,Chu J,Raymond A,Pleasance S,Coope R,Wildung MR,Ritland CE,Bousquet J,Jones SJ,Bohlmann J,Birol I

    更新日期:2015-12-08 00:00:00

  • Genetic Diversity and Gene Family Expansions in Members of the Genus Entamoeba.

    abstract::Amoebiasis is the third-most common cause of mortality worldwide from a parasitic disease. Although the primary etiological agent of amoebiasis is the obligate human parasite Entamoeba histolytica, other members of the genus Entamoeba can infect humans and may be pathogenic. Here, we present the first annotated refere...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz009

    authors: Wilson IW,Weedall GD,Lorenzi H,Howcroft T,Hon CC,Deloger M,Guillén N,Paterson S,Clark CG,Hall N

    更新日期:2019-03-01 00:00:00

  • Evolution of Chromosomal Clostridium botulinum Type E Neurotoxin Gene Clusters: Evidence Provided by Their Rare Plasmid-Borne Counterparts.

    abstract::Analysis of more than 150 Clostridium botulinum Group II type E genomes identified a small fraction (6%) where neurotoxin-encoding genes were located on plasmids. Seven closely related (134-144 kb) neurotoxigenic plasmids of subtypes E1, E3, and E10 were characterized; all carried genes associated with plasmid mobilit...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw017

    authors: Carter AT,Austin JW,Weedmark KA,Peck MW

    更新日期:2016-03-02 00:00:00

  • Sex-Biased Gene Expression and Dosage Compensation on the Artemia franciscana Z-Chromosome.

    abstract::Males and females of Artemia franciscana, a crustacean commonly used in the aquarium trade, are highly dimorphic. Sex is determined by a pair of ZW chromosomes, but the nature and extent of differentiation of these chromosomes is unknown. Here, we characterize the Z chromosome by detecting genomic regions that show lo...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz053

    authors: Huylmans AK,Toups MA,Macon A,Gammerdinger WJ,Vicoso B

    更新日期:2019-04-01 00:00:00

  • OASes and STING: adaptive evolution in concert.

    abstract::OAS (2'-5'-oligoadenylate synthases) proteins and cyclic GMP-AMP synthase (cGAS, gene symbol: MB21D1) patrol the cytoplasm for the presence of foreign nucleic acids. Upon binding to double-stranded RNA or double-stranded DNA, OAS proteins and cGAS produce nucleotide second messengers to activate RNase L and STING (sti...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evv046

    authors: Mozzi A,Pontremoli C,Forni D,Clerici M,Pozzoli U,Bresolin N,Cagliani R,Sironi M

    更新日期:2015-03-09 00:00:00

  • Transition to an Aquatic Habitat Permitted the Repeated Loss of the Pleiotropic KLK8 Gene in Mammals.

    abstract::Kallikrein related peptidase 8 (KLK8; also called neuropsin) is a serine protease that plays distinct roles in the skin and hippocampus. In the skin, KLK8 influences keratinocyte proliferation and desquamation, and activates antimicrobial peptides in sweat. In the hippocampus, KLK8 affects memory acquisition. Here, we...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx239

    authors: Hecker N,Sharma V,Hiller M

    更新日期:2017-11-01 00:00:00

  • The potential role of sexual conflict and sexual selection in shaping the genomic distribution of Mito-nuclear genes.

    abstract::Mitochondrial interactions with the nuclear genome represent one of life's most important co-evolved mutualisms. In many organisms, mitochondria are maternally inherited, and in these cases, co-transmission between the mitochondrial and nuclear genes differs across different parts of the nuclear genome, with genes on ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evu063

    authors: Dean R,Zimmer F,Mank JE

    更新日期:2014-05-01 00:00:00

  • Protein subcellular relocalization in the evolution of yeast singleton and duplicate genes.

    abstract::Gene duplication is the primary source of new genes, but the mechanisms underlying the functional divergence and retention of duplicate genes are not well understood. Because eukaryotic proteins are localized to subcellular structures and localization can be altered by a single amino acid replacement, it was recently ...

    journal_title:Genome biology and evolution

    pub_type: 信件

    doi:10.1093/gbe/evp021

    authors: Qian W,Zhang J

    更新日期:2009-07-22 00:00:00

  • Successive Losses of Central Immune Genes Characterize the Gadiformes' Alternate Immunity.

    abstract::Great genetic variability among teleost immunomes, with gene losses and expansions of central adaptive and innate components, has been discovered through genome sequencing over the last few years. Here, we demonstrate that the innate Myxovirus resistance gene (Mx) is lost from the ancestor of Gadiformes and the closel...

    journal_title:Genome biology and evolution

    pub_type: 信件

    doi:10.1093/gbe/evw250

    authors: Solbakken MH,Rise ML,Jakobsen KS,Jentoft S

    更新日期:2016-12-31 00:00:00

  • Complex Gene Loss and Duplication Events Have Facilitated the Evolution of Multiple Loricrin Genes in Diverse Bird Species.

    abstract::The evolution of a mechanically resilient epidermis was a key adaptation in the transition of amniotes to a fully terrestrial lifestyle. Skin appendages usually form via a specialized type of programmed cell death known as cornification which is characterized by the formation of an insoluble cornified envelope (CE). M...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz054

    authors: Davis AC,Greenwold MJ,Sawyer RH

    更新日期:2019-03-01 00:00:00

  • Predicting the Stability of Homologous Gene Duplications in a Plant RNA Virus.

    abstract::One of the striking features of many eukaryotes is the apparent amount of redundancy in coding and non-coding elements of their genomes. Despite the possible evolutionary advantages, there are fewer examples of redundant sequences in viral genomes, particularly those with RNA genomes. The factors constraining the main...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw219

    authors: Willemsen A,Zwart MP,Higueras P,Sardanyés J,Elena SF

    更新日期:2016-10-12 00:00:00

  • Comparative Phylogenomic Assessment of Mitochondrial Introgression among Several Species of Chipmunks (Tamias).

    abstract::Many species are not completely reproductively isolated, resulting in hybridization and genetic introgression. Organellar genomes, such as those derived from mitochondria (mtDNA) and chloroplasts, introgress frequently in natural systems; however, the forces shaping patterns of introgression are not always clear. Here...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evw254

    authors: Sarver BA,Demboski JR,Good JM,Forshee N,Hunter SS,Sullivan J

    更新日期:2017-01-01 00:00:00

  • Male Mutation Bias Is the Main Force Shaping Chromosomal Substitution Rates in Monotreme Mammals.

    abstract::In many species, spermatogenesis involves more cell divisions than oogenesis, and the male germline, therefore, accumulates more DNA replication errors, a phenomenon known as male mutation bias. The extent of male mutation bias (α) is estimated by comparing substitution rates of the X, Y, and autosomal chromosomes, as...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx155

    authors: Link V,Aguilar-Gómez D,Ramírez-Suástegui C,Hurst LD,Cortez D

    更新日期:2017-09-01 00:00:00

  • Pattern of DNA Methylation in Daphnia: Evolutionary Perspective.

    abstract::DNA methylation is an evolutionary ancient epigenetic modification that is phylogenetically widespread. Comparative studies of the methylome across a diverse range of non-conventional and conventional model organisms is expected to help reveal how the landscape of DNA methylation and its functions have evolved. Here, ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy155

    authors: Kvist J,Gonçalves Athanàsio C,Shams Solari O,Brown JB,Colbourne JK,Pfrender ME,Mirbahai L

    更新日期:2018-08-01 00:00:00

  • Mitochondrial Genome Evolution and a Novel RNA Editing System in Deep-Branching Heteroloboseids.

    abstract::Discoba (Excavata) is an evolutionarily important group of eukaryotes that includes Jakobida, with the most bacterial-like mitochondrial genomes known, and Euglenozoa, many of which have extensively fragmented mitochondrial genomes. However, little is known about the mitochondrial genomes of Heterolobosea, the third m...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx086

    authors: Yang J,Harding T,Kamikawa R,Simpson AGB,Roger AJ

    更新日期:2017-05-01 00:00:00

  • Sequencing angiosperm plastid genomes made easy: a complete set of universal primers and a case study on the phylogeny of saxifragales.

    abstract::Plastid genomes are an invaluable resource for plant biological studies. However, the number of completely sequenced plant plastid genomes is still small compared with the vast number of species. To provide an alternative generalized approach, we designed a set of 138 pairs of universal primers for amplifying (termed ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evt063

    authors: Dong W,Xu C,Cheng T,Lin K,Zhou S

    更新日期:2013-01-01 00:00:00

  • Organellar Genomes from a ∼5,000-Year-Old Archaeological Maize Sample Are Closely Related to NB Genotype.

    abstract::The story of how preColumbian civilizations developed goes hand-in-hand with the process of plant domestication by Mesoamerican inhabitants. Here, we present the almost complete sequence of a mitochondrial genome and a partial chloroplast genome from an archaeological maize sample collected at the Valley of Tehuacán, ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx048

    authors: Pérez-Zamorano B,Vallebueno-Estrada M,Martínez González J,García Cook A,Montiel R,Vielle-Calzada JP,Delaye L

    更新日期:2017-04-01 00:00:00

  • The Structure of a Conserved Telomeric Region Associated with Variant Antigen Loci in the Blood Parasite Trypanosoma congolense.

    abstract::African trypanosomiasis is a vector-borne disease of humans and livestock caused by African trypanosomes (Trypanosoma spp.). Survival in the vertebrate bloodstream depends on antigenic variation of Variant Surface Glycoproteins (VSGs) coating the parasite surface. In T. brucei, a model for antigenic variation, monoall...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evy186

    authors: Abbas AH,Silva Pereira S,D'Archivio S,Wickstead B,Morrison LJ,Hall N,Hertz-Fowler C,Darby AC,Jackson AP

    更新日期:2018-09-01 00:00:00

  • Core Genes Evolve Rapidly in the Long-Term Evolution Experiment with Escherichia coli.

    abstract::Bacteria can evolve rapidly under positive selection owing to their vast numbers, allowing their genes to diversify by adapting to different environments. We asked whether the same genes that evolve rapidly in the long-term evolution experiment (LTEE) with Escherichia coli have also diversified extensively in nature. ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx064

    authors: Maddamsetti R,Hatcher PJ,Green AG,Williams BL,Marks DS,Lenski RE

    更新日期:2017-04-01 00:00:00

  • Multifarious Evolutionary Pathways of a Nuclear RNA Editing Factor: Disjunctions in Coevolution of DOT4 and Its Chloroplast Target rpoC1eU488SL.

    abstract::Nuclear-encoded pentatricopeptide repeat (PPR) proteins are site-specific factors for C-to-U RNA editing in plant organelles coevolving with their targets. Losing an editing target by C-to-T conversion allows for eventual loss of its editing factor, as recently confirmed for editing factors CLB19, CRR28, and RARE1 tar...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evz032

    authors: Hein A,Brenner S,Knoop V

    更新日期:2019-03-01 00:00:00

  • Genetic Competence Drives Genome Diversity in Bacillus subtilis.

    abstract::Prokaryote genomes are the result of a dynamic flux of genes, with increases achieved via horizontal gene transfer and reductions occurring through gene loss. The ecological and selective forces that drive this genomic flexibility vary across species. Bacillus subtilis is a naturally competent bacterium that occupies ...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evx270

    authors: Brito PH,Chevreux B,Serra CR,Schyns G,Henriques AO,Pereira-Leal JB

    更新日期:2018-01-01 00:00:00

  • A broad genomic survey reveals multiple origins and frequent losses in the evolution of respiratory hemerythrins and hemocyanins.

    abstract::Hemerythrins and hemocyanins are respiratory proteins present in some of the most ecologically diverse animal lineages; however, the precise evolutionary history of their enzymatic domains (hemerythrin, hemocyanin M, and tyrosinase) is still not well understood. We survey a wide dataset of prokaryote and eukaryote gen...

    journal_title:Genome biology and evolution

    pub_type: 杂志文章

    doi:10.1093/gbe/evt102

    authors: Martín-Durán JM,de Mendoza A,Sebé-Pedrós A,Ruiz-Trillo I,Hejnol A

    更新日期:2013-01-01 00:00:00