Abstract:
BACKGROUND:Endosonographic evaluation and sampling of right colonic subepithelial lesions is technically difficult. OBJECTIVE:To evaluate the feasibility, safety, and tissue yield of a prototype front-view, forward-array, curved linear array echoendoscope in the evaluation and sampling of right colonic subepithelial lesions. SETTING:Tertiary referral center. DESIGN:Procedural and outcome data on all patients undergoing EUS evaluation of right-sided colonic and pericolonic lesions were collected during a 1-year study period. MAIN OUTCOME MEASUREMENTS:Patient demographics, clinical indication, EUS findings, EUS-FNA yield, technical success, and procedural complications. RESULTS:A total of 15 patients underwent EUS examination of right-sided colonic lesions with the prototype echoendoscope. The lesions were located in the cecum (n = 12) and the ascending colon (n = 3). The cecum was reached in all examinations within 10 minutes. Twelve patients had subepithelial lesions detected during colonoscopy. Findings included 6 extrinsic compressions from an adjacent normal structure, 1 calcified lymph node, 1 ovarian cyst, 1 prolapsed appendiceal orifice, 1 GI stromal tumor, 1 appendiceal mucocele, and 1 lymphoma. Two patients were evaluated for a pericolonic lesion seen on CT; findings included focal diverticulitis and a metastatic lymph node. In the patient evaluated for an infiltrative mass with previous nondiagnostic biopsies, colonic histoplasmosis was diagnosed. FNA was performed in 6 patients and provided diagnostic samples in 5 (83%). No procedure- or FNA-related complications were reported. CONCLUSIONS:Endosonographic evaluation and sampling of right-sided colonic subepithelial lesions with the prototype front-view, forward-array, curved linear array echoendoscope is feasible and safe. The yield of FNA is high, consistent with applications in the upper GI tract.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Nguyen-Tang T,Shah JN,Sanchez-Yague A,Binmoeller KFdoi
10.1016/j.gie.2010.03.1126subject
Has Abstractpub_date
2010-09-01 00:00:00pages
606-10issue
3eissn
0016-5107issn
1097-6779pii
S0016-5107(10)01483-5journal_volume
72pub_type
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pub_type: 临床试验,杂志文章,多中心研究
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