Homocysteine enhances transmigration of rat monocytes through a brain capillary endothelial cell monolayer via ICAM-1.

abstract：BACKGROUND:Intracranial aneurysms (IAs) are life-threatening lesions known within the literature to be found incidentally during routine angiographic workup for carotid artery stenosis (CAS). As IAs are associated with vascular shear stress, it is reasonable to expect that altered flow demands within the anterior circu...

journal_title：Current neurovascular research

authors： Rosenbaum MD,Heiferman DM,Raslan OA,Martin B,Dominguez JF,de la Peña PM,Ashley WW,Rosenblum JD,Germanwala AV

更新日期：2019-01-01 00:00:00

abstract：:N-methyl-D-aspartate receptors (NMDA-Rs) activation has been implicated in various forms of synaptic plasticity depending on the receptor subtypes involved. However, the contribution of NR2A and NR2B subunits in glycine-induced long-term potentiation (LTP) of miniature excitatory postsynaptic currents (mEPSCs) in laye...

journal_title：Current neurovascular research

authors： Li YH,Wang J

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Iron homeostasis disorder and neuroinflammation are the most commonly known factors that promote the occurrence and development of cognitive impairment in people. Dexmedetomidine has an anti-inflammatory effect, and it reduces the incidence of postoperative cognitive dysfunction. Therefore, the aim of this s...

journal_title：Current neurovascular research

authors： Guo F,Kang J,Tan J,Wang Y,Jia L,Xu H

更新日期：2020-01-01 00:00:00

abstract：:Brain edema following stroke is a critical clinical problem due to its association with increased morbidity and mortality. Despite its significance, present treatment for brain edema simply provides symptomatic relief due to the fact that molecular mechanisms underlying brain edema remain poorly understood. The presen...

journal_title：Current neurovascular research

authors： Higashida T,Peng C,Li J,Dornbos D 3rd,Teng K,Li X,Kinni H,Guthikonda M,Ding Y

更新日期：2011-02-01 00:00:00

abstract：:Dendritic cells (DC) play a key role in determining the appropriate immune response to invading pathogens and tolerance to self antigens. Here I review the evidence that dendritic cell functions may be tuned by the sympathetic nervous system via the local release of norepinephrine. In the presence of antigens or micro...

journal_title：Current neurovascular research

authors： Maestroni GJ

更新日期：2005-04-01 00:00:00

abstract：:Disruption of the blood-spinal cord barrier (BSCB) and microvascular changes leading to reduction of blood supply represent hallmarks of spinal cord secondary injury causing further deterioration of the traumatized patient. Injury to the blood vessels starts with prominent hemorrhage and generation of inflammation. Fu...

journal_title：Current neurovascular research

authors： Graumann U,Ritz MF,Hausmann O

更新日期：2011-11-01 00:00:00

abstract：:Physiologic functioning of the cerebrovenous system is indispensable for maintaining normal brain function. However, in contrast to the cerebroarterial system, the cerebral venous return is not routinely investigated. Combined high-resolution echo-colour-Doppler (ECD) and transcranial colour coded Doppler sonography (...

journal_title：Current neurovascular research

authors： Menegatti E,Zamboni P

更新日期：2008-11-01 00:00:00

abstract：:Understanding the role of nicotinamide (NIC) in different cell systems represents a significant challenge in several respects. Recently, NIC has been reported to have diverse roles during cell biology. In the absence of NIC, sirtuin protein activity is enhanced and pyrazinamidase/nicotinamidase 1 (PNC1) expression, an...

journal_title：Current neurovascular research

authors： Chong ZZ,Lin SH,Li F,Maiese K

更新日期：2005-10-01 00:00:00

abstract：:Ununited peripheral nerves represent attractive site for connectivity with neuroprostheses because their predictable internal topography allows precise sorting of motor and sensory signals. Also transplantation of bone marrow mesenchymal stem cells (BMSCs) is increasingly recognized as an effective method of restore t...

journal_title：Current neurovascular research

authors： Wu W,Zhang S,Chen Y,Liu H

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The most valid model for vascular cognitive impairment (VCI) is the mouse bilateral common carotid artery stenosis (BCAS), whose behavioral outcomes are supposedly affected by the remote ischemic conditioning (RIC) through the induction of autophgy. We hope to determine whether RIC contributes to the neuropr...

journal_title：Current neurovascular research

authors： Wang H,Zhang Q,Xu Y,Bian H,Si C,Yan Z,Zhu M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Acute Ischemic Stroke (AIS) represents an economic challenge for health systems all over the globe. Changes of neuroactive steroids have been found in different neurological diseases. We have previously demonstrated that old patients with AIS show changes of plasma cortisol and estradiol concentrations, in t...

journal_title：Current neurovascular research

authors： Casas S,Perez AF,Mattiazzi M,Lopez J,Folgueira A,Gargiulo-Monachelli GM,Gonzalez Deniselle MC,De Nicola AF

更新日期：2017-01-01 00:00:00

abstract：:Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS). The acquired immune system plays a central role in the pathogenesis of MS although target antigens and effector mechanisms are still poorly defined. Studies in animal models of infectious or autoimmune encephalomyelitis suggest that the ...

journal_title：Current neurovascular research

authors： Hemmer B,Cepok S,Zhou D,Sommer N

更新日期：2004-04-01 00:00:00

abstract：:Timing of treatment of aneurysmal subarachnoid hemorrhage has been controversial. This retrospective study was designed to access the safety and efficacy among cohorts of different timing of endovascular treatment patients with aneurysmal subarachnoid hemorrhage. A database of patients with aneurysmal subarachnoid hem...

journal_title：Current neurovascular research

authors： Qian Z,Peng T,Liu A,Li Y,Jiang C,Yang H,Wu J,Kang H,Wu Z

更新日期：2014-02-01 00:00:00

abstract：:Activated platelets shed microparticles, which contain a variety of growth factors central to angiogenesis and neurogenesis. The aim of this study was to explore whether platelet derived microparticles (PMP) can boost endogenous neural stem cells dependent repair mechanisms following stroke in a rat model. To examine ...

journal_title：Current neurovascular research

authors： Hayon Y,Dashevsky O,Shai E,Brill A,Varon D,Leker RR

更新日期：2012-08-01 00:00:00

abstract：:Diabetes is associated with deficits in memory and cognitive functions and sustained inflammation. Recently, involvement of NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) has been postulated in many cognitive functions, immune system and inflammation. Despite of role of NF-κB in inflammation, a...

journal_title：Current neurovascular research

authors： Datusalia AK,Sharma SS

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The prognostic value of White Blood Cell (WBC) counts and C-reactive Protein (CRP) in clinical outcomes of Acute Ischemic Stroke (AIS) patients after Intravenous Thrombolysis (IVT) remains unknown. We investigated the association of WBC counts and CRP with 3-month functional outcomes and all-cause mortality ...

journal_title：Current neurovascular research

authors： Qu X,Shi J,Cao Y,Zhang M,Xu J

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Dynamin-related protein 1 (DRP1) is a GTPase involved in mitochondrial fission, mitochondrial protein import, and drug sensitivity, suggesting an association with cancer progression. This study was conducted to evaluate the prognostic significance of DRP1 in glioblastoma multiforme (GBM). METHODS:DRP1 expre...

journal_title：Current neurovascular research

authors： Cheng WY,Chow KC,Chiao MT,Yang YC,Shen CC

更新日期：2020-01-01 00:00:00

abstract：:A stress response consisting of elevated levels of cortisol and catecholamines is common after acute stroke. The plasma levels of natriuretic peptides are known to be elevated after ischemic stroke, but the relations of these neurohormonal systems in the acute phase of stroke and their impact on long-term prognosis ha...

journal_title：Current neurovascular research

authors： Anne M,Juha K,Timo M,Mikko T,Olli V,Kyösti S,Heikki H,Vilho M

更新日期：2007-08-01 00:00:00

abstract：:Angiogenesis is associated with improved neurologic recovery after cerebral ischemia. Human bone marrow mesenchymal stem cells (hMSCs) have been successfully used to treat ischemic stroke and were shown to induce the expression of a number of neurotrophic factors including VEGF, epidermal growth factor (EGF) and basic...

journal_title：Current neurovascular research

authors： Ma XL,Liu KD,Li FC,Jiang XM,Jiang L,Li HL

更新日期：2013-05-01 00:00:00

abstract：:Hematopoietic stem cells (HSCs) have long been defined as a cell with the capacity to repopulate the hematopoietic system of a lethally irradiated host. In clinical medicine, this property has been employed to reconstitute an individual's diseased hematopoietic system following ablation with a healthy, normal-function...

journal_title：Current neurovascular research

authors： Chan RJ,Yoder MC

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:Recently, a few studies have shown that non-traditional lipid parameters are associated with the hemorrhagic transformation (HT) and the clinical outcome of ischemic stroke. However, the role of non-traditional lipid parameters in ischemic stroke patients treated with intravenous thrombolysis remains unclear....

journal_title：Current neurovascular research

authors： Luo Y,Chen J,Yan XL,Jin H,Sun X,Guo ZN,Yang Y

更新日期：2021-01-01 00:00:00

abstract：:Elevated alkaline phosphatase (ALP) levels are associated with cerebral small vascular diseases, such as silent brain infarction and cerebral white matter hyperintensity (cWMH), but few prospective data are available for cerebral microbleeds (CMBs). The aim of the study was to investigate associations between serum AL...

journal_title：Current neurovascular research

authors： Liu J,Wang D,Li J,Xiong Y,Liu B,Wei C,Wu S,Liu M

更新日期：2016-01-01 00:00:00

abstract：:Alzheimer's disease is a progressive disorder that results in the loss of cognitive function and memory. Although traditionally defined by the presence of extracellular plaques of amyloid-beta peptide aggregates and intracellular neurofibrillary tangles in the brain, more recent work has begun to focus on elucidating ...

journal_title：Current neurovascular research

authors： Chong ZZ,Li F,Maiese K

更新日期：2005-01-01 00:00:00

abstract：:This study aimed to establish an experimental exudative age-related macular degeneration (AMD) model in the common marmoset (Callithrix jacchus), which is a small New World monkey. Choroidal neovascularization (CNV) was induced by laser irradiation on the left eye of each animal under anesthesia. Eight laser spots wer...

journal_title：Current neurovascular research

authors： Shimazawa M,Masuda T,Nakamura S,Miwa M,Nakamura K,Hara H

更新日期：2015-01-01 00:00:00

abstract：:Stroke has been shown to lead to depressive disorders, anxiety disorders and other emotional consequences. Although the cause of these disorders is a subject of debate, stroke has clearly been shown to lead to the production of pro-inflammatory cytokines, which we hypothesized to play a role in the production of post-...

journal_title：Current neurovascular research

authors： Bossù P,Salani F,Cacciari C,Picchetto L,Cao M,Bizzoni F,Rasura M,Caltagirone C,Robinson RG,Orzi F,Spalletta G

更新日期：2009-08-01 00:00:00

abstract：:Serotonin (5-hydroxytryptamine, 5-HT) is an important neurotransmitter that modulates N-methyl-D-aspartate (NMDA) receptor activity by binding to several different 5-HT receptor subtypes. In the present study, we used whole-cell patch-clamp recordings in transverse slice preparations to test the role of 5-HT receptors...

journal_title：Current neurovascular research

authors： Xiang K,Zhao X,Li Y,Zheng L,Wang J,Li YH

更新日期：2016-01-01 00:00:00

abstract：:Selective serotonin reuptake inhibitors (SSRIs) improve cognition in patients with stroke and increase the expression of brain-derived neurotrophic factor (BDNF) in the rat hippocampus. However, the effects of SSRIs on cognition and BDNF level in vascular dementia (VaD) patients are largely unknown. We performed an op...

journal_title：Current neurovascular research

authors： Liu X,Zhang J,Sun D,Fan Y,Zhou H,Fu B

更新日期：2013-08-19 00:00:00

abstract：:In multiple sclerosis (MS) plaques are known to be venocentric; in addition, MS lesions and peripheral venous disorders share a number of key features. To date, however, despite the anatomical relationship between MS lesions and the venous system, no information on the intracranial venous haemodynamics of MS is availa...

journal_title：Current neurovascular research

authors： Zamboni P,Menegatti E,Bartolomei I,Galeotti R,Malagoni AM,Tacconi G,Salvi F

更新日期：2007-11-01 00:00:00

abstract：:In preterm infants, neurological signs and clinical manifestations of brain damage are limited criteria for diagnosis of neurologic sequelae. Early indicators of brain damage are needed and currently some specific biochemical markers of brain injury are investigated to assess regional brain damage after perinatal asph...

journal_title：Current neurovascular research

authors： Giuseppe D,Sergio C,Pasqua B,Giovanni LV,Salvatore C,Frigiola A,Petra H,Maurizio A

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:An impaired cerebrospinal venous drainage was postulated to be a cofactor in the multifactorial pathogenesis of multiple sclerosis (MS). Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by abnormalities of the main extracranial cerebrospinal venous outflow routes, which can be detected by ...

journal_title：Current neurovascular research

authors： Caprio MG,Marr K,Gandhi S,Jakimovski D,Hagemeier J,Weinstock-Guttman B,Zivadinov R,Mancini M

更新日期：2017-01-01 00:00:00