Imaging adoptive cell transfer based cancer immunotherapy.

Abstract:

:The prospect of mobilizing the power of the immune system in the fight against cancer has fascinated generations of immunologists. After decades of sporadic successes scattered amongst frequent failures, the field of tumor immunology is now poised to take advantage of a greatly improved understanding of the molecular and cellular mechanisms of immune tolerance. Further enhancing the prospects of cancer immunotherapy are technological advantages that have resulted in sophisticated diagnostic and immune monitoring approaches. Amongst these approaches, molecular imaging has the potential to play a transformational role in the development of highly efficient immune therapies. This brief review outlines recent significant steps in this direction, and discusses strategies to incorporate molecular imaging in the design of the next generation of experimental and clinical cell-based immune interventions against cancer.

journal_name

Curr Pharm Biotechnol

authors

Rabinovich BA,Radu CG

doi

10.2174/138920110792246528

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

672-84

issue

6

eissn

1389-2010

issn

1873-4316

pii

BSP/CPB/E-Pub/0090-11-6

journal_volume

11

pub_type

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