Vascular endothelial growth factor genetic polymorphisms and haplotypes in women with migraine.

abstract：:Genes involved in the production of nitric oxide (NO) have been suggested as genetic factors for migraine. It has been studied whether polymorphisms in the genes encoding for different types of NO synthase (NOS) could be involved in the liability to migraine; however, most studies yield negative results. The pentanucl...

journal_title：DNA and cell biology

authors： Jia S,Ni J,Chen S,Jiang Y,Dong W,Gao Y

更新日期：2011-02-01 00:00:00

abstract：:The G0S19 genes are members of the "small inducible" family of genes, which have similar exon-intron organizations and encode secreted proteins with similar dispositions of cysteine and proline residues. G0S19-1 mRNA is increased shortly after the addition of lectin or cycloheximide to cultured human blood mononuclear...

journal_title：DNA and cell biology

authors： Blum S,Forsdyke RE,Forsdyke DR

更新日期：1990-10-01 00:00:00

abstract：:DNA methylation of CYP17 (steroid 17 alpha-hydroxylase) was studied in bovine adrenocortical cells, which lose the capacity to express this tissue-specific gene in culture by phenotypic switching. Restriction enzyme digestions, and sequencing of a lambda clone of a second CYP17 gene (CYP17A2), showed that there are at...

journal_title：DNA and cell biology

authors： Hornsby PJ,Yang L,Raju SG,Maghsoudlou SS,Lala DS,Nallaseth FS

更新日期：1992-06-01 00:00:00

abstract：:Epulopiscium sp. type B, a member of the Firmicutes, is a large (up to 300 microm), cigar-shaped bacterial symbiont of surgeonfish that propagates itself by forming multiple intracellular offspring. This unusual form of reproduction is an apparent modification of a developmental program used by some Firmicutes to prod...

journal_title：DNA and cell biology

authors： Ward RJ,Clements KD,Choat JH,Angert ER

更新日期：2009-02-01 00:00:00

abstract：:In the present study, the domain IIIs of all four dengue virus (DENV) serotypes were connected sequentially to construct the tandem domain III. The resulting DNA fragment was then cloned into pBAD/Topo ThioFusion plasmid. After induction, the Escherichia coli expression protein was purified and used to immunize BALB/c...

journal_title：DNA and cell biology

authors： Chen S,Yu M,Jiang T,Deng Y,Qin C,Qin E

更新日期：2007-06-01 00:00:00

abstract：:In a systematic approach to identify interferon-gamma (IFN-gamma)-regulated host effector molecules, we found several members of the 65 kDa guanylate-binding proteins (GBPs) highly upregulated. During extensive characterization of these guanosine triphosphatases (GTPases), we identified discrepancies between the clone...

journal_title：DNA and cell biology

authors： Konermann C,Kresse A,Beuter-Gunia C,Würthner J,Degrandi D,Pfeffer K,Beer S

更新日期：2007-12-01 00:00:00

abstract：:A safe and effective adjuvant is important to develop vaccines against highly pathogenic avian influenza virus. Chitosan, a derivative from the natural amino polysaccharide chitin, has been proved to be an effective adjuvant for inactivated influenza virus vaccine. In this study, protective immunity in mice provided b...

journal_title：DNA and cell biology

authors： Chang H,Li X,Teng Y,Liang Y,Peng B,Fang F,Chen Z

更新日期：2010-09-01 00:00:00

abstract：:Uterine corpus endometrial carcinoma (UCEC) is a common malignancy in the female reproductive system, associated with high morbidity and mortality. Despite the high prevalence of UCEC, molecular understanding of uterine endothelium tumorigenesis remains poorly understood. In this study, we reported that transcription ...

journal_title：DNA and cell biology

authors： Li Q,Lei Y,Du W

更新日期：2018-05-01 00:00:00

abstract：:The sugars will eventually be exported transporters (SWEET) gene family is a glycoprotein gene family that can regulate the transport of sugar in plants and plays an important role in plant growth and development, as well as in response to environmental stress. In this study, Kentucky bluegrass (cv. Baron) seedlings w...

journal_title：DNA and cell biology

authors： Zhang R,Niu K,Ma H

更新日期：2020-09-01 00:00:00

abstract：:The aim of this work was to express a eukaryotic pre-protein in Escherichia coli so that it could be obtained intact, without cleavage, by bacterial leader peptidase. To this end, cDNA coding for honeybee prepromelittin was ligated to the 3' end of genes coding for truncated forms of either Protein A or beta-galactosi...

journal_title：DNA and cell biology

authors： He M,Liu H,Austen B

更新日期：1994-08-01 00:00:00

abstract：:Human monoclonal antibodies (HuMAbs) demonstrate great potential for passive immunotherapy against HIV-1. The gp41 transmembrane envelope glycoprotein of HIV has an important role in the pathogenicity of AIDS and importantly displays considerably less hypervariability than the gp120 surface envelope HIV glycoprotein, ...

journal_title：DNA and cell biology

authors： Cao C,Bai Y,Holloway MJ,Edgeworth RL,Jackson EA Jr,Cotropia J,Ugen KE

更新日期：2004-12-01 00:00:00

abstract：:We have determined the expression pattern of all 11 human replication-dependent histone H3 genes in three fetal human tissues (bladder, liver, and lung) and in eight human cell lines by RNase protection assay. In the fetal human tissues, all 11 genes were expressed to a varied extent. However, the relative contributio...

journal_title：DNA and cell biology

authors： Koessler H,Doenecke D,Albig W

更新日期：2003-04-01 00:00:00

abstract：:CYP24A1 is overexpressed in colorectal cancer, and the reason for the dysregulation of CYP24A1 in colorectal cancer is still unknown. In the present study, experiments were designed to test whether CYP24A1 inhibition facilitated the antiproliferative effect of 1,25(OH)2D3. In addition, the role of methylation in the r...

journal_title：DNA and cell biology

authors： Sun H,Jiang C,Cong L,Wu N,Wang X,Hao M,Liu T,Wang L,Liu Y,Cong X

更新日期：2018-09-01 00:00:00

abstract：:In the current study, we evaluated the potential effect of a novel sphingosine kinase 1 (SphK1) activator, K6PC-5, on oxygen-glucose deprivation (OGD)/reoxygenation-induced damages to myocardial cells. We demonstrated that K6PC-5 increased intracellular sphingosine-1-phosphate (S1P) content and remarkably inhibited OG...

journal_title：DNA and cell biology

authors： Shao JJ,Peng Y,Wang LM,Wang JK,Chen X

更新日期：2015-11-01 00:00:00

abstract：:NANOG is a critical homeodomain transcription factor responsible for maintaining embryonic stem cell (ESC) self-renewal and pluripotency. In the present study, we isolated, sequenced, and characterized the NANOG gene in buffalo ESC-like cells. Here, we demonstrated that NANOG mRNA is expressed as multiple isoforms and...

journal_title：DNA and cell biology

authors： Singh N,Sharma R,George A,Singla SK,Palta P,Manik R,Chauhan MS,Singh D

更新日期：2012-05-01 00:00:00

abstract：:The pathogenic strains of Vibrio cholerae that cause acute enteric infections in humans are derived from environmental nonpathogenic strains. To track the evolution of pathogenic V. cholerae and identify potential precursors of new pathogenic strains, we analyzed 324 environmental or clinical V. cholerae isolates for ...

journal_title：DNA and cell biology

authors： Rahman MH,Biswas K,Hossain MA,Sack RB,Mekalanos JJ,Faruque SM

更新日期：2008-07-01 00:00:00

abstract：:Six identical cDNA clones corresponding to an RNA of 1685 nucleotides that is enriched in mouse sperm compared with testis were isolated from a mouse testis cDNA library. The sequence of these clones corresponds to the 16S mitochondrial RNA plus an inverted repeat of 120 bp covalently joined to the 5' end of the RNA. ...

journal_title：DNA and cell biology

authors： Villegas J,Zárraga AM,Muller I,Montecinos L,Werner E,Brito M,Meneses AM,Burzio LO

更新日期：2000-09-01 00:00:00

abstract：:We examined the chromosomal basis for the synthesis of tissue (ovary, endometrium/placenta, and peri-implantation blastocyst) isoforms of cytochrome P450 aromatase in the pig. DNA fragments derived from three distinct porcine aromatase chromosomal genes were cloned and characterized. The porcine type III aromatase gen...

journal_title：DNA and cell biology

authors： Choi I,Troyer DL,Cornwell DL,Kirby-Dobbels KR,Collante WR,Simmen FA

更新日期：1997-06-01 00:00:00

abstract：:Gene delivery from tissue engineering scaffold is a novel strategy in regulating long-term growth and function of cells in vitro culture. In this study, a hepatocyte growth factor plasmid/polyetherimide (pHGF/PEI) polyplex delivering alginate (AL)/galactosylated chitosan (GC) (pHGF/PEI-AL/GC) sponge scaffold was prepa...

journal_title：DNA and cell biology

authors： Gao C,Yang Y,Zhang Y,Qian M,Yang J

更新日期：2020-03-01 00:00:00

abstract：:The breast cancer gene 1 (BRCA1) is a tumor suppressor, and mutations or epigenetic inactivation will increase the risk of breast cancer oncogenesis. The current research aimed to explore the relationship between BRCA1 expression, prognosis, and tumor immunity in hepatocellular carcinoma (HCC). In this study, BRCA1 ex...

journal_title：DNA and cell biology

authors： Mei J,Wang R,Xia D,Yang X,Zhou W,Wang H,Liu C

更新日期：2020-10-01 00:00:00

abstract：:The promoters of mammalian striated muscle actin gene contain binding sites for a number of transcription factors. Examples are the CArG boxes, which bind a protein identical to or related to serum response factor (SRF), E boxes, which bind myogenic determination factors such as MyoD and myogenin, and -CCGCCC- motifs,...

journal_title：DNA and cell biology

authors： Davey HW,Kelly JK,Wildeman AG

更新日期：1995-07-01 00:00:00

abstract：:Mouse vimentin intermediate filaments (IFs) reconstituted in vitro were analyzed for their capacity to select certain DNA sequences from a mixture of about 500-bp-long fragments of total mouse genomic DNA. The fragments preferentially bound by the IFs and enriched by several cycles of affinity binding and polymerase c...

journal_title：DNA and cell biology

authors： Wang X,Tolstonog G,Shoeman RL,Traub P

更新日期：1996-03-01 00:00:00

abstract：:Endocytosis of the five rat somatostatin receptor subtypes (SSTR1-5) was investigated in transfected HEK cells by biochemical ligand binding assays and confocal microscopic analysis. Phenylarsine oxide-sensitive internalization of SSTR1-3 is dependent on SST-14 or SST-28, whereas only the octacosapeptide triggers this...

journal_title：DNA and cell biology

authors： Roth A,Kreienkamp HJ,Nehring RB,Roosterman D,Meyerhof W,Richter D

更新日期：1997-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) are an important class of small, noncoding, regulatory RNAs found to be involved in regulating a wide variety of important cellular processes by the sequence-specific inhibition of gene expression. Viruses have evolved a number of mechanisms to take advantage of the regulatory potential of this high...

journal_title：DNA and cell biology

authors： Dykxhoorn DM

更新日期：2007-04-01 00:00:00

abstract：:Mutations in the mitochondrial genome (mtDNA) are associated with different types of cancer, specifically colorectal cancer (CRC). However, few studies have been performed on precancerous lesions, such as ulcerative colitis (UC) lesions and adenomatous polyps (AP). The aim of this study was to identify mtDNA mutations...

journal_title：DNA and cell biology

authors： Kassem AM,El-Guendy N,Tantawy M,Abdelhady H,El-Ghor A,Abdel Wahab AH

更新日期：2011-11-01 00:00:00

abstract：:The major surface promoter of human hepatitis B virus can produce three distinct groups of S transcripts. The initiation sites of these transcripts are in close proximity. Encompassing the ATG for the middle surface protein, the largest S transcript (+1) encodes the middle surface protein whereas the other two (+20 an...

journal_title：DNA and cell biology

authors： Kuo YL,Ting LP

更新日期：1997-05-01 00:00:00

abstract：:A decrease in gap junctional, intercellular communication (GJIC) has been associated with cells neoplastically transformed by a variety of factors. To investigate the role of the Ras oncogene product in gap junction function, a panel of murine C3H10T1/2 (10T1/2) fibroblasts was constructed in which the levels of ras g...

journal_title：DNA and cell biology

authors： Brownell HL,Narsimhan RP,Corbley MJ,Mann VM,Whitfield JF,Raptis L

更新日期：1996-06-01 00:00:00

abstract：:Regenerative medicine is a new interdisciplinary field in biomedical science, which aims at the repair or replacement of the defective tissue or organ by congenital defects, age, injury, or disease. Various cell-related techniques such as stem cell-based biotherapy are a hot topic in the current press, and stem cell r...

journal_title：DNA and cell biology

authors： Guo J,Wang H,Hu X

更新日期：2013-10-01 00:00:00

abstract：:Congenital cataract refers to a lens opacity caused by multiple etiological factors, including genetic mutation, abnormal metabolism of the lens, and infection. Currently, there are >100 known disease-causing genes as well as 60 known mutations in the Cx46 gene (Gap junction alpha-3, GJA3) associated with congenital c...

journal_title：DNA and cell biology

authors： Li H,Jiang H,Rong R,Jiang J,Ji D,Song W,Xia X

更新日期：2020-10-01 00:00:00

abstract：:The aim of this study is to discuss the hypothesis that expression of plasma atherosclerosis-associated microRNAs (miRNAs) in hyperhomocysteinemia (Hhcy) patients could predict the presence of atherosclerosis from different channels. Six plasma miRNAs (miR-145, miR-155, miR-222, miR-133, miR-217, and miR-30) selected ...

journal_title：DNA and cell biology

authors： Liu K,Xuekelati S,Zhou K,Yan Z,Yang X,Inayat A,Wu J,Guo X

更新日期：2018-03-01 00:00:00