Abstract：
:Hubs are proteins with a large number of interactions in a protein-protein interaction network. They are the principal agents in the interaction network and affect its function and stability. Their specific recognition of many different protein partners is of great interest from the structural viewpoint. Over the last few years, the structural properties of hubs have been extensively studied. We review the currently known features that are particular to hubs, possibly affecting their binding ability. Specifically, we look at the levels of intrinsic disorder, surface charge and domain distribution in hubs, as compared to non-hubs, along with differences in their functional domains.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Patil A,Kinoshita K,Nakamura Hdoi
10.3390/ijms11041930subject
Has Abstractpub_date
2010-04-26 00:00:00pages
1930-43issue
4issn
1422-0067journal_volume
11pub_type
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journal_title：International journal of molecular sciences
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更新日期：2018-07-04 00:00:00
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