Abstract:
:Lung transplantation has evolved over the past two decades as a well-recognized therapy for patients with end-stage lung diseases. However, lung transplantation has been limited, in part, due to the scarcity of donor lung organs. Previously, donor lung organs were allocated based on a potential recipient's waiting list time. However, in 2005, under the mandate of the US Government, through the Department of Health and Human Services, the lung-allocation system was changed to incorporate medical urgency and utility in order to optimize patient outcomes. Clinical factors that predicted pretransplant and 1-year post-transplant survival for each potential recipient were incorporated into a Lung Allocation Score. Early 1-year results have shown a decrease in the number of candidates on the waiting list, a decrease in the waiting time and a decrease in waiting list mortality. Outcomes after lung transplantation have been conflicting, with some centers suggesting worse outcomes and others suggesting an increased morbidity but not increased 1-year mortality. Longer follow-up of these patients will be useful to determine the utility of the Lung Allocation Score system in lung transplantation.
journal_name
Expert Rev Respir Medjournal_title
Expert review of respiratory medicineauthors
Stern E,Bhorade SMdoi
10.1586/17476348.2.4.473subject
Has Abstractpub_date
2008-08-01 00:00:00pages
473-8issue
4eissn
1747-6348issn
1747-6356journal_volume
2pub_type
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
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doi:10.1586/ers.11.35
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
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doi:10.1586/17476348.2.5.655
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
doi:10.1586/17476348.2013.842468
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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journal_title:Expert review of respiratory medicine
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abstract::Lung transplantation is the only effective treatment for many advanced lung diseases. However, long-term survival after transplantation remains relatively poor, thus limiting the application of lung transplantation to patients with end-stage disease only. Acute and chronic rejection is the main reason for allograft fa...
journal_title:Expert review of respiratory medicine
pub_type: 杂志文章
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更新日期:2007-10-01 00:00:00
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journal_title:Expert review of respiratory medicine
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更新日期:2018-08-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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更新日期:2018-02-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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更新日期:2010-08-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
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更新日期:2015-01-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章,评审
doi:10.1586/17476348.2013.847368
更新日期:2013-12-01 00:00:00
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journal_title:Expert review of respiratory medicine
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更新日期:2017-06-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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journal_title:Expert review of respiratory medicine
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更新日期:2009-12-01 00:00:00
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journal_title:Expert review of respiratory medicine
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更新日期:2010-06-01 00:00:00
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journal_title:Expert review of respiratory medicine
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journal_title:Expert review of respiratory medicine
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更新日期:2019-10-01 00:00:00
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journal_title:Expert review of respiratory medicine
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更新日期:2010-04-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章
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更新日期:2008-02-01 00:00:00
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journal_title:Expert review of respiratory medicine
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更新日期:2018-06-01 00:00:00
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journal_title:Expert review of respiratory medicine
pub_type: 杂志文章
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更新日期:2009-10-01 00:00:00