An antiproliferative ribonuclease from fruiting bodies of the wild mushroom Russula delica.

abstract：:The fungal strain EML-DML3PNa1 isolated from leaf of white dogwood (Cornus alba L.) showed strong nematicidal activity with juvenile mortality of 87.6% at a concentration of 20% fermentation broth filtrate at 3 days after treatment. The active fungal strain was identified as Aspergillus oryzae, which belongs to sectio...

journal_title：Journal of microbiology and biotechnology

authors： Kim TY,Jang JY,Jeon SJ,Lee HW,Bae CH,Yeo JH,Lee HB,Kim IS,Park HW,Kim JC

更新日期：2016-08-28 00:00:00

abstract：:Poly-gamma-glutamic acid (γ-PGA) is a natural polymer that is synthesized by Bacillus species and has been reported to have antitumor activity. The aim of this study was to investigate the effect of γ-PGA on the treatment of vaginal intraepithelial neoplasia (VAIN). A retrospective observational study on γ-PGA therapy...

journal_title：Journal of microbiology and biotechnology

authors： Koo YJ,Min KJ,Hong JH,Lee JK

更新日期：2015-07-01 00:00:00

abstract：:A Gram-negative, strictly aerobic, motile bacterial strain, designated Gsoil 124T, was isolated from a soil sample taken from a ginseng field in Pocheon Province (South Korea). The isolate contained Q-10 as the predominant lipoquinone, plus C18:1 7c and summed feature 4 (C16:1 6c and/or iso- C15:0 2-OH) as the major f...

journal_title：Journal of microbiology and biotechnology

authors： Lee HW,Ten IL,Jung HM,Liu QM,Im WT,Lee ST

更新日期：2008-06-01 00:00:00

abstract：:Many bacteria metabolize aromatic compounds via catechol as a catabolic intermediate, and possess multiple genes or clusters encoding catechol-cleavage enzymes. The presence of multiple isozyme-encoding genes is a widespread phenomenon that seems to give the carrying strains a selective advantage in the natural enviro...

journal_title：Journal of microbiology and biotechnology

authors： Shi S,Yang L,Yang C,Li S,Zhao H,Ren L,Wang X,Lu F,Li Y,Zhao H

更新日期：2020-12-11 00:00:00

abstract：:Beta-1,3-glucans enhance immune reactions such as antitumor, antibacterial, antiviral, anticoagulatory, and wound healing activities. beta-1,3-Glucans have various functions depending on the molecular weight, degree of branching, conformation, water solubility, and intermolecular association. The molecular weight of t...

journal_title：Journal of microbiology and biotechnology

authors： Shim JH,Sung KJ,Cho MC,Choi WA,Yang Y,Lim JS,Yoon DY

更新日期：2007-09-01 00:00:00

abstract：:Acetic acid is indirectly involved in cell center metabolism, and acetic acid metabolism is the core of central metabolism, affecting and regulating the production of bacteriocin. Bacteriocin is a natural food preservative that has been used in the meat and dairy industries and winemaking. In this paper, the effects o...

journal_title：Journal of microbiology and biotechnology

authors： Ge J,Kang J,Ping W

更新日期：2019-09-28 00:00:00

abstract：:A chimeric gene encoding enhanced green fluorescent protein (EGFP) and a S-layer protein from Lactobacillus brevis KCTC3102, and/or two copies of the Fc-binding Z-domain, a synthetic analog of the B-domain of protein A, was constructed and expressed in Escherichia coli BL21(DE3). The S-layer fusion proteins produced i...

journal_title：Journal of microbiology and biotechnology

authors： Khang YH,Park HY,Jeong YS,Kim JA,Kim YH

更新日期：2009-05-01 00:00:00

abstract：:To increase the availability of microalgae as producers of valuable compounds, it is necessary to develop novel systems for gene expression regulation. Among the diverse expression systems available in microalgae, none are designed to induce expression by low temperature. In this study, we explored a cold-inducible sy...

journal_title：Journal of microbiology and biotechnology

authors： Kim M,Kim J,Kim S,Jin E

更新日期：2020-11-28 00:00:00

abstract：:An efficient and simple fermentation process was developed for the production of gamma-amminobutyric acid (GABA) by Lactobacillus sakei B2-16. When the L. sakei B2-16 was cultivated in the rice bran extracts medium containing 4% sucrose, 1% yeast extract and 12% monosodium glutamate, the maximum GABA concentration rea...

journal_title：Journal of microbiology and biotechnology

authors： Kook MC,Seo MJ,Cheigh CI,Pyun YR,Cho SC,Park H

更新日期：2010-04-01 00:00:00

abstract：:This study was undertaken to evaluate the immunomodulatory effect of dead nano-sized Lactobacillus plantarum (nLp) in RAW 264.7 cells and murine primary splenocytes. nLp is a dead, shrunken, processed form of L. plantarum nF1 isolated from kimchi (a traditional Korean fermented cabbage) and is less than 1 μm in size. ...

journal_title：Journal of microbiology and biotechnology

authors： Lee HA,Kim H,Lee KW,Park KY

更新日期：2016-03-01 00:00:00

abstract：:Colorectal cancer (CRC) is regarded as one of the most common and deadly forms of cancer. Gut microbiota is vital to retain and promote several functions of intestinal. Although previous researches have shown that some gut microbiota have the abilities to inhibit tumorigenesis and prevent cancer from progressing, they...

journal_title：Journal of microbiology and biotechnology

authors： Chen C,Li H

更新日期：2020-11-28 00:00:00

abstract：:Fungal diversity during composting was investigated by culture-independent rDNA sequence analysis. Composting was carried out with pig manure and mushroom cultural waste using a field-scale composter (Hazaka system), and samples were collected at various stages. Based on partial sequence analysis of large subunit (LSU...

journal_title：Journal of microbiology and biotechnology

authors： Cho KM,Kwon EJ,Kim SK,Kambiranda DM,Math RK,Lee YH,Kim J,Yun HD,Kim H

更新日期：2009-08-01 00:00:00

abstract：:It has been well known that the use of Saccharomyces cerevisiae can cause fungemia in critically ill patients and flavone shows an antimicrobial effect on S. cerevisiae. Therefore, we have investigated the activities of thirteen flavone analogues on S. cerevisiae in our studies. Because flavonoids including flavones h...

journal_title：Journal of microbiology and biotechnology

authors： Young J,Park Y,Lee YU,Kim H,Shim YH,Ahn JH,Lim Y

更新日期：2007-03-01 00:00:00

abstract：:The biosynthesis study of antibiotics saframycin (SFM) in Streptomyces lavendulae and safracin (SAC) in Pseudomonas fluorescens demonstrated that 3-hydroxy-5-methyl-Omethyltyrosine (3h5mOmTyr), a nonproteinogenic amino acid, is the precursor of the tetrahydroisoquinoline molecular core. In the biosynthetic gene cluste...

journal_title：Journal of microbiology and biotechnology

authors： Fu CY,Tang MC,Peng C,Li L,He YL,Liu W,Tang GL

更新日期：2009-05-01 00:00:00

abstract：:Vanillyl alcohol (VA), which is abundant in Vanilla bean, has strong antioxidant activity. However, the use of VA in the food and cosmetics industries is limited, due to its low solubility in emulsion or organic solvents. Meanwhile, medium chain fatty acids and medium chain monoglycerides have antibacterial activity. ...

journal_title：Journal of microbiology and biotechnology

authors： Kim JJ,Kim HK

更新日期：2020-11-10 00:00:00

abstract：:Cellulase and xylanase are main hydrolysis enzymes for the degradation of cellulosic and hemicellulosic biomass, respectively. In this study, our aim was to develop and test the efficacy of a rapid, high-throughput method to screen hydrolytic-enzyme-producing microbes. To accomplish this, we modified the 3,5-dinitrosa...

journal_title：Journal of microbiology and biotechnology

authors： Kim JJ,Kwon YK,Kim JH,Heo SJ,Lee Y,Lee SJ,Shim WB,Jung WK,Hyun JH,Kwon KK,Kang DH,Oh C

更新日期：2014-11-28 00:00:00

abstract：:Optimal conditions for a high cell density fermentation were investigated in a recombinant Escherichia coli producing salmosin, a platelet aggregation inhibitor. The optimized carbon and nitrogen sources were glycerol 10 g/l, yeast extract 30 g/l, and bacto-tryptone 10 g/l, yielding the dry cell weight (DCW) of 10.61 ...

journal_title：Journal of microbiology and biotechnology

authors： Seo MJ,Choi HJ,Chung KH,Pyun YR

更新日期：2011-10-01 00:00:00

abstract：:Organic solvent-tolerant (OST) enzymes are widely applied in various industries due to their activity and stability in organic solvents, higher substrate solubility, and increased stereo-selectivity. However, the criteria for identifying OST enzymes largely remain unresolved. In this study, we compared the amino acid ...

journal_title：Journal of microbiology and biotechnology

authors： Dachuri VK,Lee C,Jang SH

更新日期：2018-09-28 00:00:00

abstract：:The dependence of the catalytic properties of horseradish peroxidase on the structural changes of ionic liquids was investigated with two water-miscible ionic liquids, N-butyl-3- methypyridinium tetrafluoroborate ([BMPy][BF4]) and 1-butyl- 3-methylimidazolium methylsulfate ([BMIM][MeSO4]), each of which shares an anio...

journal_title：Journal of microbiology and biotechnology

authors： Hong ES,Park JH,Yoo IK,Ryu KG

更新日期：2009-07-01 00:00:00

abstract：:The impact of overproduction of a heterologous protein on the metabolic system of host Lactococcus lactis was investigated. The protein expression profiles of L. lactis IL1403 containing two near-identical plasmids that expressed high- and low-level of the green fluorescent protein (GFP) were examined via shotgun prot...

journal_title：Journal of microbiology and biotechnology

authors： Kim M,Jin Y,An HJ,Kim J

更新日期：2017-07-28 00:00:00

abstract：:Hepatitis B core antigen (HBcAg) is an important serological marker used in the diagnosis of hepatitis B virus (HBV) infections. In the current study, a fast and efficient preparative purification protocol for truncated HBcAg from Escherichia coli disruptate was developed. The recombinant HBcAg was first captured by a...

journal_title：Journal of microbiology and biotechnology

authors： Ho CW,Tan WS,Chong FC,Ling TC,Tey BT

更新日期：2009-04-01 00:00:00

abstract：:Particle size and metal species are important to both soil microbial toxicity and phytotoxicity in the soil ecosystem. The effects of CuO and ZnO nanoparticles (NPs) and microparticles (MPs) on soil microbial toxicity, phytotoxicity, and bioaccumulation in two crops (Cucumis sativus and Zea mays) were estimated in a s...

journal_title：Journal of microbiology and biotechnology

authors： Kim S,Sin H,Lee S,Lee I

更新日期：2013-09-28 00:00:00

abstract：:Bioethanol production from lignocellulose is considered as a sustainable biofuel supply. However, the low cellulose hydrolysis efficiency limits the cellulosic ethanol production. The cellulase is strongly inhibited by the major end product cellobiose, which can be relieved by the addition of β-glucosidase. In this st...

journal_title：Journal of microbiology and biotechnology

authors： Tang H,Hou J,Shen Y,Xu L,Yang H,Fang X,Bao X

更新日期：2013-11-28 00:00:00

abstract：:During menopausal transition, the imbalance of estrogen causes body weight gain. Although gut microbiome dysbiosis has been reported in postmenopausal obesity, it is not clear whether there is any difference in the microbiome profile between dietary-induced obesity and postmenopausal obesity. Therefore, in this study,...

journal_title：Journal of microbiology and biotechnology

authors： Choi S,Hwang YJ,Shin MJ,Yi H

更新日期：2017-12-28 00:00:00

abstract：:Lipoteichoic acid (LTA), a cell wall component of gram-positive bacteria, is recognized by Toll-like receptor 2, expressed on certain mammalian cell surfaces, initiating signaling cascades that include nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and mitogen-activated protein kinase. There ar...

journal_title：Journal of microbiology and biotechnology

authors： Kim S,Kim HE,Kang B,Lee YW,Kim H,Chung DK

更新日期：2017-10-28 00:00:00

abstract：:Energy-efficient metabolic responses were often noted in high-productive cultures. To better understand these metabolic responses, an investigation into the relationship between metabolic responses and energy regulation was conducted via a comparative analysis among cultures with different energy source supplies. Both...

journal_title：Journal of microbiology and biotechnology

authors： Sun YT,Zhao L,Ye ZY,Fan L,Liu XP,Tan WS

更新日期：2013-11-28 00:00:00

abstract：:A gene (acas) designated as alpha-amylase was cloned from Arthrobacter chlorophenolicus A6. The multiple amino acid sequence analysis and functional expression of acas revealed that this gene really encoded an amylosucrase (ASase) instead of alpha-amylase. In fact, the recombinant enzyme exhibited typical ASase activi...

journal_title：Journal of microbiology and biotechnology

authors： Seo DH,Jung JH,Choi HC,Cho HK,Kim HH,Ha SJ,Yoo SH,Cha J,Park CS

更新日期：2012-09-01 00:00:00

abstract：:The task of improving a fungal strain is highly time-consuming due to the requirement of a large number of flasks in order to obtain a library with enough diversity. In addition, fermentations (particularly those for fungal cells) are typically performed in high-volume (100-250 ml) shake-flasks. In this study, for lar...

journal_title：Journal of microbiology and biotechnology

authors： Shin WS,Lee D,Kim S,Jeong YS,Chun GT

更新日期：2017-01-28 00:00:00

abstract：:Whitening effect, tyrosinase inhibitions, and cytotoxicity of neoagarotetraose were measured after purification from hydrolyzed agar by gel filtration chromatography. In melanoma B16F10 cells, melanin content of neoagarotetraose-treated cells was as same as that treated by kojic acid or arbutin. In addition, tyrosinas...

journal_title：Journal of microbiology and biotechnology

authors： Jang MK,Lee DG,Kim NY,Yu KH,Jang HJ,Lee SW,Jang HJ,Lee YJ,Lee SH

更新日期：2009-10-01 00:00:00

abstract：:Rhodococcus sp. strain p52, a previously isolated dibenzofuran degrader, could effectively inhibit the growth of cyanobacteria, including species of Microcystis, Anabaena, and Nodularia. When strain p52 was inoculated at the concentration of 7.7×10(7) CFU/ml, 93.5% of exponentially growing Microcystis aeruginosa (7.3×...

journal_title：Journal of microbiology and biotechnology

authors： Wang MH,Peng P,Liu YM,Jia RB,Li L

更新日期：2013-02-01 00:00:00