Antioxidant-like effects and protective action of transcranial magnetic stimulation in depression caused by olfactory bulbectomy.

Abstract:

:We studied the effects of transcranial magnetic stimulation (TMS, 60 Hz and 0.7 mT for 4 h/day for 14 days) on oxidative and cell damage caused by olfactory bulbectomy (OBX) in Wistar rats. The levels of lipid peroxidation products and caspase-3 were enhanced by OBX, whereas it prompted a reduction in reduced glutathione (GSH) content and antioxidative enzymes activities. The treatment with TMS reverted towards normality the biomarkers indicative of oxidative stress and apoptosis. In conclusion, our data show that TMS induced a protection against cell and oxidative damage induced by OBX, as well as they support the hypothesis that oxidative stress may play an important role in depression.

journal_name

Neurochem Res

journal_title

Neurochemical research

authors

Tasset I,Drucker-Colín R,Peña J,Jimena I,Montilla P,Medina FJ,Túnez I

doi

10.1007/s11064-010-0172-9

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

1182-7

issue

8

eissn

0364-3190

issn

1573-6903

journal_volume

35

pub_type

杂志文章
  • [3H]ketanserin binding in human brain postmortem.

    abstract::This study aimed at comparing the binding characteristics of [3H]ketanserin, a high-affinity serotonin 2A (5-HT2A) receptor antagonist, in the prefrontal cortex, hippocampus and striatum of human brain post-mortem. The results indicated the presence of a single population of binding sites in all the regions investigat...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1023/a:1027366413289

    authors: Marazziti D,Rossi A,Palego L,Giannaccini G,Naccarato A,Lucacchini A,Cassano GB

    更新日期:1997-06-01 00:00:00

  • Activation of p42 mitogen-activated protein kinase by glutamate in cultured radial glia.

    abstract::The effect of L-glutamate (Glu) and its structural analogs N-methyl-D-aspartate (NMDA), kainate (KA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA), on the activation of p42 mitogen activated protein kinase (MAPK) was examined in cultured chick radial glia cells, namely retinal Muller cells and cerebe...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1023/a:1027345808746

    authors: López-Colomé AM,Ortega A

    更新日期:1997-06-01 00:00:00

  • Inhibition of neuron-specific CREB dephosphorylation is involved in propofol and ketamine-induced neuroprotection against cerebral ischemic injuries of mice.

    abstract::Propofol and ketamine may provide certain degree of neuroprotection, but the underlying mechanism remains unclear to date. The cAMP response element-binding protein (CREB) was proposed that its phosphorylation at Ser133 (P-CREB) constituted a convergence point involved in neuroprotection. The purpose of this study was...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-011-0582-3

    authors: Shu L,Li T,Han S,Ji F,Pan C,Zhang B,Li J

    更新日期:2012-01-01 00:00:00

  • The gamma subunits of the native GABAA/benzodiazepine receptors.

    abstract::Subunit-specific antibodies to all the gamma subunit isoforms described in mammalian brain (gamma(1), gamma(2S), gamma(2L), and gamma(3) have been made. The proportion of GABA(A) receptors containing each gamma subunit isoform in various brain regions has been determined by quantitative immunoprecipitation. In all tes...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/BF02529132

    authors: Khan ZU,Gutiérrez A,Miralles CP,De Blas AL

    更新日期:1996-02-01 00:00:00

  • In vitro binding of [14C]2,5-hexanedione to rat neuronal cytoskeletal proteins.

    abstract::2,5-Hexanedione (2,5-HD) induces central-peripheral axonpathy characterized by the accumulation of 10-nm neurofilaments proximal to the nodes of Ranvier and a Wallerian-type degeneration. It has been postulated that neurofilament crosslinking may be involved in the production of this axonopathy. A potential initiating...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/BF00965151

    authors: Lanning CL,Wilmarth KR,Abou-Donia MB

    更新日期:1994-09-01 00:00:00

  • DHA Attenuates Hypoxia/Reoxygenation Injury by Activating SSeCKS in Human Cerebrovascular Pericytes.

    abstract::Docosahexaenoic acid (DHA) can alleviate cerebral ischemia/reperfusion injury by reducing blood-brain barrier permeability and maintaining its integrity, accompanied by an increased Ang-1/Ang-2 ratio; however, the underlying mechanisms of these effects remain unclear. Src-suppressed C kinase substrates (SSeCKS), a sub...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-019-02915-0

    authors: Yu Y,Fang H,Qiu Z,Xia Z,Zhou B

    更新日期:2020-02-01 00:00:00

  • Double ligand ELISA technique for the estimation of antibodies to brain tissue antigens in patients with neurological disorders.

    abstract::A double ligand enzyme-linked immunosorbent assay (ELISA) has been developed to detect antibodies against brain tissue antigens in the sera of patients with neurological diseases. The sera were tested on human white matter homogenate. The technique consists of successive incubations with the human serum to be tested, ...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/BF00964651

    authors: Bologa L,Hofstetter W,Schonenberger K,Jacque C,Herschkowitz N

    更新日期:1985-04-01 00:00:00

  • Amine precursor amino acid therapy: from neurochemical basis to clinical aspects.

    abstract::The particulars regarding the amine precursor therapy for treatment of neuropsychiatric disorders and their neurochemical background are described historically. Furthermore, peculiar or artificial amino acids which are metabolized into the brain amine or their derivatives and promised their clinical application are al...

    journal_title:Neurochemical research

    pub_type: 杂志文章,评审

    doi:10.1007/BF02529142

    authors: Nakajima T

    更新日期:1996-02-01 00:00:00

  • All Trans Retinoic Acid Attenuates Markers of Neuroinflammation in Rat Brain by Modulation of SIRT1 and NFκB.

    abstract::Alcohol abuse affects several neurological pathways and causes significant alterations in the brain. Abstention from alcohol causes only a marginal decrease in oxidative stress and neuro inflammation. Our previous studies had shown that an active metabolite of vitamin A, all trans retinoic acid (ATRA), ameliorates alc...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-018-2595-7

    authors: Priyanka SH,Syam Das S,Thushara AJ,Rauf AA,Indira M

    更新日期:2018-09-01 00:00:00

  • Preparation and characterization of antisera to the myelin-associated glycoprotein.

    abstract::Rabbits were immunized with the myelin-associated glycoprotein (MAG) that had been purified from isolated rat brain myelin by selective extraction with lithium diiodosalicylate (LIS) and phenol followed by preparative SDS gel electrophoresis. Antibodies to MAG were detected qualitatively by immunodiffusion and quantit...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/BF00964417

    authors: Quarles RH,Johnson D,Brady RO,Sternberger NH

    更新日期:1981-10-01 00:00:00

  • Turnover rate of molecular species of sphingomyelin in rat brain.

    abstract::Turnover rate of individual molecular species of sphingomyelin of adult rat brain myelin and microsomal membranes was determined after an intracerebral injection of 100 microCi of [C3H3]choline. Myelin and microsomal membrane sphingomyelins were isolated from the rest of the lipids. The individual molecular species of...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/BF00964414

    authors: LeBaron FN,Sanyal S,Jungalwala FB

    更新日期:1981-10-01 00:00:00

  • Histone Acetylation Regulation in Sleep Deprivation-Induced Spatial Memory Impairment.

    abstract::Sleep disorders negatively affect cognition and health. Recent evidence has indicated that chromatin remodeling via histone acetylation regulates cognitive function. This study aimed to investigate the possible roles of histone acetylation in sleep deprivation (SD)-induced cognitive impairment. Results of the Morris w...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-016-1937-6

    authors: Duan R,Liu X,Wang T,Wu L,Gao X,Zhang Z

    更新日期:2016-09-01 00:00:00

  • Effect of chronic administration of ethanol on the regulation of tyrosine kinase phosphorylation of the GABAA receptor subunits in the rat brain.

    abstract::One of the many pharmacological targets of ethanol is the GABA inhibitory system, and chronic ethanol (CE) is known to alter the polypeptide levels of the GABA(A )receptor subunits in rat brain regions. In the present study, we investigated the regulation of the tyrosine kinase phosphorylation of the GABA(A) receptor ...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-007-9288-y

    authors: Marutha Ravindran CR,Mehta AK,Ticku MK

    更新日期:2007-07-01 00:00:00

  • Immediate and long-term effects of 5,7-dihydroxytryptamine on rat striatal serotonergic neurons measured using in vivo voltammetry.

    abstract::The immediate and long-term effects of the selective serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-DHT) on rat striatal serotonergic neurons were examined after its intracerebroventricular administration using in vivo voltammetry. Extracellular concentration of 5-hydroxyindoles increased immediately following i...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1023/a:1022460216822

    authors: Nakazato T,Akiyama A

    更新日期:1998-01-01 00:00:00

  • Neuroprotective effects of idebenone against pilocarpine-induced seizures: modulation of antioxidant status, DNA damage and Na(+), K (+)-ATPase activity in rat hippocampus.

    abstract::The current study investigated the neuroprotective activity of idebenone against pilocarpine-induced seizures and hippocampal injury in rats. Idebenone is a ubiquinone analog with antioxidant, and ATP replenishment effects. It is well tolerated and has low toxicity. Previous studies reported the protective effects of ...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-014-1236-z

    authors: Ahmed MA

    更新日期:2014-02-01 00:00:00

  • Intracellular signaling in primary sensory neurons and persistent pain.

    abstract::During evolution, living organisms develop a specialized apparatus called nociceptors to sense their environment and avoid hazardous situations. Intense stimulation of high threshold C- and Adelta-fibers of nociceptive primary sensory neurons will elicit pain, which is acute and protective under normal conditions. A f...

    journal_title:Neurochemical research

    pub_type: 杂志文章,评审

    doi:10.1007/s11064-008-9711-z

    authors: Cheng JK,Ji RR

    更新日期:2008-10-01 00:00:00

  • The interaction of (1-4)-fragment of thymosin beta 4 with calmodulin-sensitive cAMP phosphodiesterase from hypothalamus.

    abstract::Evidence was accumulated indicating that cyclic nucleotides are involved in regulation of growth, differentiation and function of lymphoid cells. It was previously shown that the N-fragment (1-4) of thymosin beta 4 (Ac-Ser-Asp-Lys-Pro-OH) inhibits in vivo the entry of cell populations into S-phase. In the course of th...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/BF00995153

    authors: Voelter W,Kapuzniotu A,Mihelic M,Gurvits B,Abrahamian G,Galoyan A

    更新日期:1995-01-01 00:00:00

  • The 21-aminosteroid U-74389F attenuates hyperexpression of GAP-43 and NADPH-diaphorase in the spinal cord of wobbler mouse, a model for amyotrophic lateral sclerosis.

    abstract::The wobbler mouse suffers an autosomal recessive mutation producing severe neurodegeneration and astrogliosis in spinal cord. It has been considered a model for amyotrophic lateral sclerosis. We have studied in these animals the expression of two proteins, the growth-associated protein (GAP-43) and the NADPH-diaphoras...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1023/a:1020918310281

    authors: González Deniselle MC,González SL,Lima AE,Wilkin G,De Nicola AF

    更新日期:1999-01-01 00:00:00

  • Hypoxia-induced lipid peroxidation in rat brain and protective effect of carnitine and phosphocreatine.

    abstract::The exposure to hypobaric hypoxia increased lipid peroxidation as indicated by thiobarbituric acid-reactive substances [TBARS] in rat brain. Plasma lactate/pyruvate ratio was used as a marker of hypoxia. We compared the protective effect of alpha-tocopherol with the effect of L-carnitine or phosphocreatine. Rats pretr...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1023/a:1020339530924

    authors: Rauchová H,Koudelová J,Drahota Z,Mourek J

    更新日期:2002-09-01 00:00:00

  • Astrocytes Provide Metabolic Support for Neuronal Synaptic Function in Response to Extracellular K.

    abstract::It is an honour to have this opportunity write an article in recognition of the immense contributions of Bruce Ransom to the field of glial research. For me (BAM) personally there are many highlights both as a colleague and a friend that come to mind when I reflect on the many years that I have known Bruce. My own ent...

    journal_title:Neurochemical research

    pub_type: 杂志文章,评审

    doi:10.1007/s11064-017-2315-8

    authors: MacVicar BA,Choi HB

    更新日期:2017-09-01 00:00:00

  • Catecholamine level in cerebrospinal fluid of epileptics.

    abstract::We estimated catecholamine levels in CSF of 15 epileptics and 75 non-neurological patients utilizing a high performance liquid chromatograph with a highly sensitive fluorometer and found the following results: The dopamine (DA) levels in males were significantly higher than those in females, while norepinephrine (NE) ...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/BF00965900

    authors: Hiramatsu M,Fujimoto N,Mori A

    更新日期:1982-10-01 00:00:00

  • A metabolic basis for Alzheimer disease.

    abstract::Most studies of Alzheimer's disease (AD) have focused on a single precipitating alteration as the etiological event rather than global changes closely linked to aging. Recent evidence suggests that the most significant of these global changes are metabolic. Here we present data indicating that metabolic rate, nutritio...

    journal_title:Neurochemical research

    pub_type: 杂志文章,评审

    doi:10.1023/a:1025678510480

    authors: Perry G,Nunomura A,Raina AK,Aliev G,Siedlak SL,Harris PL,Casadesus G,Petersen RB,Bligh-Glover W,Balraj E,Petot GJ,Smith MA

    更新日期:2003-10-01 00:00:00

  • Evidence of Nicotine-Induced, Curare-Insensitive, Behavior in Planarians.

    abstract::Planarians are rapidly developing into very useful research subjects in pharmacology and neuroscience research. Here we report that curare, a cholinergic nicotinic receptor antagonist, alleviates the nicotine-induced planarian seizure-like movements (pSLM) by up to 50 % at equimolar concentrations of nicotine and cura...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-015-1512-6

    authors: Pagán OR,Montgomery E,Deats S,Bach D,Baker D

    更新日期:2015-10-01 00:00:00

  • Sepsis associated encephalopathy studied by MRI and cerebral spinal fluid S100B measurement.

    abstract::The pathogenesis of sepsis associated encephalopathy (SAE) is not yet clear: the blood-brain barrier (BBB) disruption has been indicated among the possible causative mechanisms. S100B, a calcium binding protein, originates in the central nervous system but it can be also produced by extra-cerebral sources; it is passi...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-008-9907-2

    authors: Piazza O,Cotena S,De Robertis E,Caranci F,Tufano R

    更新日期:2009-07-01 00:00:00

  • Mycobacterium leprae binds to a 25-kDa phosphorylated glycoprotein of human peripheral nerve.

    abstract::Mycobacterium leprae, the causative agent of leprosy, specifically invades and destroys the peripheral nerve, which results in the main clinical manifestation of the disease. Little is known about the bacteria-nerve protein interaction. We show in the present work that M leprae binds to a 25 kDa glycoprotein from huma...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1023/a:1022471331168

    authors: Suneetha LM,Satish PR,Korula RJ,Suneetha SK,Job CK,Balasubramanian AS

    更新日期:1998-06-01 00:00:00

  • Regulation of Glioma Cells Migration by DYRK2.

    abstract::Dual-specificity tyrosine-regulated kinase 2 (DYRK2), a protein kinase that phosphorylates its substrates on serine/threonine, is expressed in numerous human tumors, but little is known about its role in the pathophysiology of glioma. In this study, we made an effort to explore the expression and function in human gli...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-017-2345-2

    authors: Shen Y,Zhang L,Wang D,Bao Y,Liu C,Xu Z,Huang W,Cheng C

    更新日期:2017-11-01 00:00:00

  • The chronological characteristics of SOD1 activity and inflammatory response in the hippocampi of STZ-induced type 1 diabetic rats.

    abstract::Because it appears that oxidative stress and inflammation are implicated with disease pathogenesis in the diabetic brain, many researchers have used streptozotocin (STZ)-induced diabetic animals to study superoxide production and the effects of superoxide scavengers like Cu,Zn-superoxide dismutase (SOD1). However, man...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1007/s11064-010-0280-6

    authors: Yi SS,Hwang IK,Kim DW,Shin JH,Nam SM,Choi JH,Lee CH,Won MH,Seong JK,Yoon YS

    更新日期:2011-01-01 00:00:00

  • BDNF and trkB mRNA expression in neurons of the neonatal mouse barrel field cortex: normal development and plasticity after cauterizing facial vibrissae.

    abstract::Development of the central somatosensory system is profoundly modulated by the sensory periphery. Cauterization of facial whiskers alters the segregation pattern of barrels in rodents only during a few days just after birth (critical period). Although a molecular basis of the segregation of barrel neurons and the crit...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1023/a:1022075508176

    authors: Singh TD,Mizuno K,Kohno T,Nakamura S

    更新日期:1997-07-01 00:00:00

  • Inhibition of rat brain Na+, K+-ATPase activity induced by homocysteine is probably mediated by oxidative stress.

    abstract::The objective of the present study was to investigate the effects of preincubation of hippocampus homogenates in the presence of homocysteine or methionine on Na+, K+-ATPase and Mg2+-ATPase activities in synaptic membranes of rats. Homocysteine significantly inhibited Na+, K+-ATPase activity, whereas methionine had no...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1023/a:1013907104585

    authors: Streck EL,Zugno AI,Tagliari B,Franzon R,Wannmacher CM,Wajner M,Wyse AT

    更新日期:2001-11-01 00:00:00

  • Regulation of the ecto-nucleotidase pathway in rat hippocampal nerve terminals.

    abstract::Ecto-nucleotidases play a pivotal role in terminating the signalling via ATP and in producing adenosine, a neuromodulator in the nervous system. We have now investigated the pattern of adenosine formation with different concentrations of extracellular ATP in rat hippocampal nerve terminals. It was found that adenosine...

    journal_title:Neurochemical research

    pub_type: 杂志文章

    doi:10.1023/a:1012392719601

    authors: Cunha RA

    更新日期:2001-09-01 00:00:00