Lactate response to short term exercise with elevated starting levels.

Abstract:

:A model that describes the blood lactate concentration (BLC) dynamics [BLC(t)] of a Wingate Anaerobic Test (WAnT) as a function of (a) BLC at the start of exercise (BLC(0)), (b) extra-vascular increase in lactate (A), (c) two corresponding velocity constants of appearance (k (1)) and disappearance (k (2)) of lactate into and out of the blood requires that BLC(0) is equal to resting BLC (BLC(rest)). We developed a model that considers an elevated BLC(0). 19 males performed WAnTs with warm-ups increasing (p < 0.001) BLC(0). The goodness of each individual fit improved (p < 0.05) if the difference between BLC(rest) and BLC(0) (DeltaBLC) was higher than 1.0 mmol l(-1). All differences between old and new model (p < 0.05) in A, k (1) and k (2) were interrelated with and increased with DeltaBLC (p < 0.05). The new model well describes BLC(t) and prevents substantial errors concerning lactate generation and dynamics if BLC(0) is elevated by more than 1.0 mmol l(-1).

journal_name

Eur J Appl Physiol

authors

Beneke R,Wittekind A,Mühling M,Bleif I,Leithäuser RM

doi

10.1007/s00421-010-1481-z

subject

Has Abstract

pub_date

2010-09-01 00:00:00

pages

215-8

issue

1

eissn

1439-6319

issn

1439-6327

journal_volume

110

pub_type

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