Uterine sperm-egg transfer: a cost-effective alternative to IVF in anovulatory women.

Abstract:

:Anovulatory women can prove extremely challenging patients in the fertility clinic, particularly if they are unresponsive to standard protocols of clomiphene citrate. Katayama and colleagues now report (in this issue) an intriguing option, which yielded surprisingly high success rates in 16 selected young (age <36years) patients. Very low-dose progressive stimulation (35 IU gonadotrophins per day for 7days, followed by 75IU per day for about 5days if necessary), combined with the direct transfer of unfertilized eggs and prepared spermatozoa, resulted in a birth rate of 50%. The authors note that, at the time of oocyte retrieval, no spontaneous ovulation had occurred in any patient.

journal_name

Reprod Biomed Online

authors

Ahuja KK,Andonov M,Linara E,Simons E

doi

10.1016/j.rbmo.2010.03.010

subject

Has Abstract

pub_date

2010-06-01 00:00:00

pages

707-8

issue

6

eissn

1472-6483

issn

1472-6491

pii

S1472-6483(10)00135-5

journal_volume

20

pub_type

杂志文章
  • An evidence-based scoring system for prioritizing mosaic aneuploid embryos following preimplantation genetic screening.

    abstract::The aim of this study was to devise an evidence-based scoring system for prioritizing mosaic aneuploid embryos for transfer. A retrospective analysis was performed of all sequential cytogenetic and molecular results on chorionic villi samples (n = 72,472) and products of conception (n = 3806) analysed at a single cent...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2018.01.005

    authors: Grati FR,Gallazzi G,Branca L,Maggi F,Simoni G,Yaron Y

    更新日期:2018-04-01 00:00:00

  • Candida albicans experimental infection: effects on human sperm motility, mitochondrial membrane potential and apoptosis.

    abstract::Studies suggest Candida albicans infection has a negative effect on sperm function, including fertilizing ability. Assisted reproduction treatment using spermatozoa from a patient with unrecognized C. albicans infection did not result in fertilization. Preliminary evidence suggested an effect on sperm motility and apo...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/s1472-6483(10)60125-3

    authors: Burrello N,Salmeri M,Perdichizzi A,Bellanca S,Pettinato G,D'Agata R,Vicari E,Calogero AE

    更新日期:2009-04-01 00:00:00

  • Patient evaluation of infertility management in an ISO 9001:2008-certified centre for reproductive medicine.

    abstract::Quality management according to ISO 9001:2008 guidelines includes infertility care quality assessment and improvement. This study aimed to describe the development process of a questionnaire for infertility management. A literature review, qualitative interviews with experts and patients resulted in a content-valid an...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2011.11.020

    authors: Van den Broeck U,Spiessens C,Dancet E,Bakelants E,Vrancken A,Demyttenaere K,Enzlin P,D'Hooghe T

    更新日期:2012-03-01 00:00:00

  • Total fertilization failure and molecular abnormalities in metaphase II oocytes.

    abstract::Total fertilization failures (TFF) are rare events of IVF by intracytoplasmic sperm injection (ICSI). When male factor is excluded, the lack of identifiable aetiological criteria raises the question of the reliable clinical management. The goal of this study was to identify molecular abnormalities in metaphase II (MII...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/s1472-6483(10)60404-x

    authors: Gasca S,Reyftmann L,Pellestor F,Rème T,Assou S,Anahory T,Dechaud H,Klein B,De Vos J,Hamamah S

    更新日期:2008-12-01 00:00:00

  • A new title to an old song: some observations on the conduct of meta-analyses.

    abstract::The purpose of this commentary is to draw attention to some unsatisfactory features in the way that meta-analyses are presented in assisted reproduction journals. These features will be illustrated with reference to recently published papers. An appeal will be made for a more fastidious and rigorous approach to this s...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2013.05.019

    authors: Walters E

    更新日期:2013-11-01 00:00:00

  • Three-dimensional power Doppler sonography of the (sub)endometrium and angiogenic cytokine concentrations.

    abstract::The aim of this study was to determine the correlation between three-dimensional power Doppler sonography (3D-PDS) of the (sub)endometrium and concentrations of angiogenic cytokines in patients attending an IVF programme. A total of 42 patients was included in a prospective, non-randomized clinical study. 3D-PDS of th...

    journal_title:Reproductive biomedicine online

    pub_type: 临床试验,杂志文章

    doi:10.1016/s1472-6483(10)60202-7

    authors: Siemer J,Binder H,Willeke C,Dorn C,Reinsberg J,Fimmers R,van der Ven H,Schild RL

    更新日期:2008-08-01 00:00:00

  • No association between endogenous LH and pregnancy in a GnRH antagonist protocol: part I, corifollitropin alfa.

    abstract::The relationship between endogenous LH concentrations and ongoing pregnancy rates among normogonadotrophic patients undergoing ovarian stimulation in a gonadotrophin-releasing hormone antagonist protocol were examined. In the Engage trial, 1506 patients received corifollitropin alfa (150 μg) or daily recombinant FSH (...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.rbmo.2011.06.015

    authors: Doody KJ,Devroey P,Leader A,Witjes H,Mannaerts BM

    更新日期:2011-10-01 00:00:00

  • Outcome of ICSI using zona pellucida-bound spermatozoa and conventionally selected spermatozoa.

    abstract::This study aimed to investigate whether the spermatozoa-zona pellucida binding test is able to select spermatozoa with higher fertilization potential and higher rate of successful embryo development. This prospective study was performed with metaphase II (MII) oocytes retrieved from couples undergoing intracytoplasmic...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2009.09.020

    authors: Paes Almeida Ferreira de Braga D,Iaconelli A Jr,Cássia Sávio de Figueira R,Madaschi C,Semião-Francisco L,Borges E Jr

    更新日期:2009-12-01 00:00:00

  • How old is too old? A contribution to the discussion on age limits for assisted reproduction technique access.

    abstract::In 2012, the Czech Republic established the women's age limit for access to assisted reproduction techniques at age 49 years. In this paper, the acceptability of this age limit from the children's perspective in the Czech Republic is assessed. Although the necessity of balancing the interests of parents and children i...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2015.01.017

    authors: Kocourková J,Konečná H,Burcin B,Kučera T

    更新日期:2015-05-01 00:00:00

  • Role of LH in ovarian stimulation: considerations.

    abstract::The role of LH in ovarian stimulation continues to be controversial. Most observational studies on both gonadotrophin-releasing hormone (GnRH) agonist and GnRH antagonist protocols failed to show an effect on ongoing pregnancy likelihood of punctually measured 'low' or 'high' endogenous LH concentrations during ovaria...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,评审

    doi:10.1016/s1472-6483(10)61990-6

    authors: Griesinger G,Diedrich K

    更新日期:2006-04-01 00:00:00

  • Anti-Müllerian hormone remains highly expressed in human cumulus cells during the final stages of folliculogenesis.

    abstract::This study evaluated whether anti-Müllerian hormone (AMH) was differentially expressed in cumulus (CC) and granulosa (GC) cells from large antral and pre-ovulatory follicles collected from individual follicles in women undergoing in-vitro maturation (IVM) or IVF treatment. Expression studies of AMH, AMH receptor 2, FS...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2010.12.005

    authors: Grøndahl ML,Nielsen ME,Dal Canto MB,Fadini R,Rasmussen IA,Westergaard LG,Kristensen SG,Yding Andersen C

    更新日期:2011-04-01 00:00:00

  • The treatment of infertility and its historical context.

    abstract::The objective of this review is to analyse and integrate into a semi-historical background the alternative treatments available for the alleviation of infertility. Data are presented on their causes and success, using compilations of data reported in the literature along with personal experience. Results are expressed...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,评审

    doi:10.1016/s1472-6483(10)61601-x

    authors: Da Motta EL,Serafini P

    更新日期:2002-07-01 00:00:00

  • Pregnancy outcome after multifetal pregnancy reduction of triplets to twins versus reduction to singletons.

    abstract:RESEARCH QUESTION:Does fetal reduction of triplet pregnancies to singleton result in superior obstetric and neonatal outcomes compared with triplets reduced to twins? DESIGN:A historical cohort study including 285 trichorionic and dichorionic triplet pregnancies that underwent abdominal fetal reduction at 11-14 weeks ...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2019.12.014

    authors: Zemet R,Haas J,Bart Y,Barzilay E,Zloto K,Argaman N,Schwartz N,Weisz B,Yinon Y,Mazaki-Tovi S,Lipitz S

    更新日期:2020-03-01 00:00:00

  • Effects of lifestyle modification in polycystic ovarian syndrome.

    abstract::Polycystic ovarian syndrome (PCOS) is a common endocrine condition with reproductive and metabolic consequences, including anovulation, infertility and an increased prevalence of diabetes mellitus. Obesity, central obesity and insulin resistance are strongly implicated in its aetiology. Dietary weight loss is recommen...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,评审

    doi:10.1016/s1472-6483(10)61182-0

    authors: Moran LJ,Brinkworth G,Noakes M,Norman RJ

    更新日期:2006-05-01 00:00:00

  • Intended parents' motivations and information and support needs when seeking extraterritorial compensated surrogacy.

    abstract::Cross-border reproductive care (CBRC) is becoming increasingly common. Little is known about the motivations and information and support needs of people who cross borders to access surrogacy. This study aimed to explore: how those considering or undertaking extraterritorial surrogacy reach their decision; what other a...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2015.08.008

    authors: Hammarberg K,Stafford-Bell M,Everingham S

    更新日期:2015-11-01 00:00:00

  • Antioxidants to reduce sperm DNA fragmentation: an unexpected adverse effect.

    abstract::Reactive oxygen species (ROS) have a negative impact on sperm DNA, leading to the formation of oxidative products such as 8-oxo-7,8-dihydroxyguanosine. This compound causes fragmentation and, thus, has a mutagenic effect. Patient treatment with oral antioxidant vitamins is, therefore, standard practice for male infert...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,多中心研究

    doi:10.1016/s1472-6483(10)60887-5

    authors: Ménézo YJ,Hazout A,Panteix G,Robert F,Rollet J,Cohen-Bacrie P,Chapuis F,Clément P,Benkhalifa M

    更新日期:2007-04-01 00:00:00

  • Very early prenatal diagnosis on coelomic cells using quantitative fluorescent polymerase chain reaction.

    abstract::Quantitative fluorescent PCR (QF-PCR) has been shown to be an accurate assay for the rapid prenatal diagnosis of chromosome disorders. The extra-embryonic coelom develops during week 4 of gestation and it can be aspirated from the following week, making coelocentesis the earliest possible method of prenatal diagnosis ...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/s1472-6483(10)62173-6

    authors: Jauniaux E,Cirigliano V,Adinolfi M

    更新日期:2003-06-01 00:00:00

  • Outlook: Roles of FSH and LH during the follicular phase: insight into natural cycle IVF.

    abstract::A mounting interest in natural cycle IVF has challenged the medical community to better understand the mechanisms controlling the follicular phase and ovulation in particular, in an effort to optimize this procedure and its outcome. For practical reasons, the advancement of the follicular phase in the menstrual cycle ...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,评审

    doi:10.1016/s1472-6483(10)60381-1

    authors: de Ziegler D,Fraisse T,de Candolle G,Vulliemoz N,Bellavia M,Colamaria S

    更新日期:2007-11-01 00:00:00

  • Kit ligand decreases the incidence of apoptosis in cultured vitrified whole mouse ovaries.

    abstract::To investigate the development of follicles and incidence of apoptosis in vitrified cultured mouse ovaries in the presence and absence of Kit ligand, 1-week-old mouse ovaries were cultured in the presence or absence of Kit ligand for 7 days. Development and function of ovarian follicles was evaluated by histology and ...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2015.01.009

    authors: Abdi S,Salehnia M,Hosseinkhani S

    更新日期:2015-05-01 00:00:00

  • Anti-Müllerian hormone in pregnant women in relation to other hormones, fetal sex and in circulation of second trimester fetuses.

    abstract::The aim of this study was to investigate the regulation of anti-Müllerian hormone (AMH) blood concentrations in mother and fetus during pregnancy. Serum concentrations of AMH, gonadotrophins, oestradiol and progesterone were measured in pregnant women in the first trimester and AMH concentrations in second-trimester f...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/s1472-6483(10)60016-8

    authors: Lutterodt M,Byskov AG,Skouby SO,Tabor A,Yding Andersen C

    更新日期:2009-05-01 00:00:00

  • Recombinant LH in ovarian stimulation.

    abstract::The advent of recombinant gonadotrophins brought significant changes in fertility therapy. Treatment options with recombinant gonadotrophins add more to knowledge on folliculogenesis and ovarian steroidogenesis. Over a decade, recombinant LH (rLH) has been used for clinical trials, and the amount of peripheral LH that...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,评审

    doi:10.1016/s1472-6483(10)61123-6

    authors: Caglar GS,Asimakopoulos B,Nikolettos N,Diedrich K,Al-Hasani S

    更新日期:2005-06-01 00:00:00

  • Preimplantation testing for chromosomal disorders improves reproductive outcome of poor-prognosis patients.

    abstract::The clinical impact of PGD was evaluated through the analysis of the reproductive outcome before and after PGD in the same group of poor prognosis IVF patients, undergoing PGD for chromosomal abnormalities. Based on a series of 2359 PGD cycles, resulting in the establishment of 498 chromosomal abnormality-free clinica...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/s1472-6483(10)60961-3

    authors: Verlinsky Y,Tur-Kaspa I,Cieslak J,Bernal A,Morris R,Taranissi M,Kaplan B,Kuliev A

    更新日期:2005-08-01 00:00:00

  • Cytogenetic testing of pregnancy loss tissue: a meta-analysis.

    abstract::Many clinics offer routine genetic testing of pregnancy loss tissue. This review presents a comprehensive literature search and meta-analysis on chromosomal abnormality rates of pregnancy loss tissue from women with a single or recurrent pregnancy loss. A total of 55 studies published since 2000 were included, analyse...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,评审

    doi:10.1016/j.rbmo.2020.02.001

    authors: Smits MAJ,van Maarle M,Hamer G,Mastenbroek S,Goddijn M,van Wely M

    更新日期:2020-06-01 00:00:00

  • Effect of uterine dimensions on live birth rates after single embryo transfer in infertile women.

    abstract:RESEARCH QUESTION:Do uterine size parameters measured by baseline transvaginal ultrasound predict live birth after single embryo transfer (SET) of a high-quality blastocyst? DESIGN:Retrospective cohort study including women undergoing their first SET between August 2010 and March 2014 at a large university hospital re...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2020.07.007

    authors: Steiner N,Ates S,Shaulov T,Tannus S,Dahan MH

    更新日期:2020-10-01 00:00:00

  • NADPH oxidase as an important source of reactive oxygen species at the mouse maternal-fetal interface: putative biological roles.

    abstract::Oxygen derivatives that comprise the large family of reactive oxygen species (ROS) are actively involved in placental biology. They are generated at the maternal-fetal interface at the level of decidual, trophoblast and mesenchymal components. In normal conditions, ROS produced in low concentrations participate in dif...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,评审

    doi:10.1016/j.rbmo.2012.03.016

    authors: Bevilacqua E,Gomes SZ,Lorenzon AR,Hoshida MS,Amarante-Paffaro AM

    更新日期:2012-07-01 00:00:00

  • Emerging technologies for the molecular study of infertility, and potential clinical applications.

    abstract::The techniques currently used to treat infertility cases are quite limited in their capabilities, due to an incomplete understanding of the molecular activities of germ cells. Fortunately, several technologies are presently being researched that should aid the understanding of the various molecular causes of germ cell...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章,评审

    doi:10.1016/s1472-6483(10)60372-0

    authors: Varghese AC,Goldberg E,Bhattacharyya AK,Agarwal A

    更新日期:2007-10-01 00:00:00

  • Blastocyst culture selects for euploid embryos: comparison of blastomere and trophectoderm biopsies.

    abstract::Preimplantation genetic diagnosis and screening improves the chances of achieving a viable pregnancy, not only free of undesired single-gene defects but also aneuploidy. In addition, improvements in vitrification provide an efficient means of preserving embryos (blastocysts). By combining trophectoderm biopsy with rec...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2013.11.018

    authors: Adler A,Lee HL,McCulloh DH,Ampeloquio E,Clarke-Williams M,Wertz BH,Grifo J

    更新日期:2014-04-01 00:00:00

  • Progressive alcohol-induced sperm alterations leading to spermatogenic arrest, which was reversed after alcohol withdrawal.

    abstract::This is a report of a 6-year follow-up of a male patient's semen parameters during heavy chronic alcohol intoxication and after withdrawal. A slowly progressive negative impact of alcohol could be observed: isolated moderate teratozoospermia was firstly noted followed by oligoasthenoteratospermia. Then a severe worsen...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/j.rbmo.2009.12.003

    authors: Sermondade N,Elloumi H,Berthaut I,Mathieu E,Delarouzière V,Ravel C,Mandelbaum J

    更新日期:2010-03-01 00:00:00

  • Achievement of pregnancy three times in the same patient during luteal GnRH agonist administration.

    abstract::Gonadotrophin-releasing hormone agonist (GnRHa) administration from the mid-luteal phase onwards is considered the gold standard of ovarian stimulation for IVF treatment. It might, however, coincide with an implanting spontaneous pregnancy. Concerns have therefore been raised with regard to the evolution of the result...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/s1472-6483(10)61794-4

    authors: Papanikolaou EG,Platteau P,Albano C,Kolibianakis E,Devroey P

    更新日期:2005-03-01 00:00:00

  • Prediction of pituitary down-regulation by evaluation of endometrial thickness in an IVF programme.

    abstract::The aim of this retrospective study was to determine whether pituitary down-regulation after gonadotrophin-releasing hormone analogue (GnRHa) administration can be accurately predicted by transvaginal ultrasonographic measurement of endometrial thickness in the presence of menstruation. All cycles of an IVF/intracytop...

    journal_title:Reproductive biomedicine online

    pub_type: 杂志文章

    doi:10.1016/s1472-6483(10)61109-1

    authors: Dogan MM,Uygur D,Alkan RN,Batioglu S,Mollamahmutoglu L

    更新日期:2004-05-01 00:00:00