Abstract:
:New technology has provided methods for collecting large amounts of data reflecting gene expression, metabolite and protein abundance, and post-translational modification of proteins. Integration of these various data sets enable the genetic mapping of many new phenotypes and facilitates the creation of network models that link genetic variation with intermediate traits leading to human disease. The first round of genome-wide association studies has not accounted for common human diseases to the extent that was expected. New phenotyping approaches and methods of data integration should bring these studies closer to their promised goals.
journal_name
Nat Medjournal_title
Nature medicineauthors
Newgard CB,Attie ADdoi
10.1038/nm0410-388subject
Has Abstractpub_date
2010-04-01 00:00:00pages
388-91issue
4eissn
1078-8956issn
1546-170Xpii
nm0410-388journal_volume
16pub_type
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