Getting biological about the genetics of diabetes.

Abstract:

:New technology has provided methods for collecting large amounts of data reflecting gene expression, metabolite and protein abundance, and post-translational modification of proteins. Integration of these various data sets enable the genetic mapping of many new phenotypes and facilitates the creation of network models that link genetic variation with intermediate traits leading to human disease. The first round of genome-wide association studies has not accounted for common human diseases to the extent that was expected. New phenotyping approaches and methods of data integration should bring these studies closer to their promised goals.

journal_name

Nat Med

journal_title

Nature medicine

authors

Newgard CB,Attie AD

doi

10.1038/nm0410-388

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

388-91

issue

4

eissn

1078-8956

issn

1546-170X

pii

nm0410-388

journal_volume

16

pub_type

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