Myelodysplastic transformation of polycythemia vera: case report and review of the literature.

Abstract:

:We report a case of refractory anemia with excess blasts (RAEB) developing in a 67-year old man with a history of polycythemia vera; results of cytogenetic and immunophenotyping studies are described. In this report the clinical, cytogenetic and hematologic features of myelodysplasia complicating polycythemia vera are reviewed. Results of immunophenotyping and cytogenetic studies, and the preponderance of cases developing after myelosuppressive therapy suggest that in the majority of cases myelodysplasia is treatment-related.

journal_name

Am J Hematol

authors

Shamdas GJ,Spier CM,List AF

doi

10.1002/ajh.2830370110

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

45-8

issue

1

eissn

0361-8609

issn

1096-8652

journal_volume

37

pub_type

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