Common HBV genotype in southeastern Iranian patients.

Abstract:

:Asymptomatic hepatitis B infection is characterized as a type of hepatitis in which hepatitis B surface antigen is present in the patient's peripheral blood despite the absence of clinical symptoms. Previous studies have shown that a particular genotype may effect clinical manifestations of hepatitis B infection; hence, the aim of the current study was to determine the frequency of hepatitis B virus genotypes among asymptomatic carriers of hepatitis B.In this experimental study, the plasma samples of 100 asymptomatic carriers were collected and tested for HBsAg and anti-HBs using ELISA. The genotype of hepatitis B virus was determined by the GAP-PCR technique. The results of this study showed that all samples were positive for hepatitis B surface antigen and anti-hepatitis B core antigen was present in 60 (60%) cases. Our results also indicated that all patients had the D genotype of hepatitis B virus.

journal_name

Arch Iran Med

authors

Eftekhari Y,Kazemi Arababadi M,Hakimi H,Rezazadeh Zarandi E

subject

Has Abstract

pub_date

2010-03-01 00:00:00

pages

147-9

issue

2

eissn

1029-2977

issn

1735-3947

pii

010132/AIM.0012

journal_volume

13

pub_type

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