Abstract:
:C-11 acetate positron emission tomography (PET) is known to have high sensitivity in detecting hepatocellular carcinoma. However, one of the shortcomings of C-11 acetate PET in the diagnosis of hepatocellular carcinoma is that C-11 acetate also accumulates in focal nodular hyperplasia, which makes it challenging to distinguish hepatocellular carcinoma form focal nodular hyperplasia when a conventional single time point PET imaging method is used. Two patients with suspected hepatocellular carcinoma and negative fluoro-deoxy-glucose PET scans underwent C-11 acetate PET dual time imaging in which both early and delayed images were acquired. One patient was subsequently confirmed having hepatocellular carcinoma while the other had focal nodular hyperplasia. C-11 acetate imaging was positive in both patients. Interestingly, in hepatocellular carcinoma the C-11 acetate activity in the delayed images is higher than in the early images while in focal nodular hyperplasia, the C-11 acetate activity decreased in the delayed image when compared with early images. Our findings suggest that dual time point imaging has potential to improve the diagnostic accuracy of C-11 acetate PET in the diagnosis of hepatocellular carcinoma.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Huo L,Wu Z,Zhuang H,Fu Z,Dang Ydoi
10.1097/RLU.0b013e3181bed06esubject
Has Abstractpub_date
2009-12-01 00:00:00pages
874-7issue
12eissn
0363-9762issn
1536-0229pii
00003072-200912000-00007journal_volume
34pub_type
杂志文章abstract::The authors examined regional cerebral blood flow by using Tc-99m HMPAO SPECT studies in a patient who received a gunshot wound to the brain. Although the presence of the retained bullet's fragments adversely affected the quality of CT images and contraindicated MRI studies, the SPECT examination did not have the same...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199408000-00012
更新日期:1994-08-01 00:00:00
abstract::A 61-year-old man with Hodgkin lymphoma (mixed type), with lymph node manifestations and extranodal and bone marrow involvement in both supra- and infradiaphragmatic locations (stage 4), had dyspnea and tachycardia on echocardiography. There were pleural and pericardial effusions and thickening of the epicardium and p...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000082666.85547.94
更新日期:2003-09-01 00:00:00
abstract::Pituitary macroadenoma constitutes a frequently misdiagnosed benign tumor. We report herein a case where such macroadenoma, a prolactinoma, was incidentally discovered in a 63-year-old man who had been referred to F-FDG PET and F-FDOPA PET imaging for a pharmacoresistant epilepsy. An increased uptake was documented fo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001721
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:To produce fluorodeoxyglucose (FDG) images with markers for normal organs and large blood vessels in patients with suspected lung cancer. METHODS:Dual isotope SPECT images were made using F-18 FDG- and Tc-99m-labeled autologous red cells. RESULTS:FDG-positive lesions are localized in relation to major structu...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199812000-00003
更新日期:1998-12-01 00:00:00
abstract::A cavernous hemangioma of the liver presented as an area of increased activity on an isotope bone scan. A review of the literature fails to reveal any previous reports of this phenomenon. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198607000-00009
更新日期:1986-07-01 00:00:00
abstract::Single-photon emission computed tomography has been proven to detect more abnormalities than planar bone scintigraphy in patients with low back pain (LBP). Both 180 degrees and 360 degrees acquisitions were performed in 24 patients with LBP to determine whether the shorter 180 degrees posterior SPECT is as accurate fo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199306000-00004
更新日期:1993-06-01 00:00:00
abstract::Leaders of private practice groups face many challenges. Establishing proper governance, having a good mission statement and business plan, having good participation by the members in administrative practice activities, and establishing proper channels of communication are some important steps. Once that is done, effi...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318223f3cc
更新日期:2011-09-01 00:00:00
abstract::Echocardiography, gated scintigraphy and contrast angiography were used to measure left ventricular ejection fractions in 20 patients with varying degrees of aortic insufficiency. There was good correlation between the radionuclide and the angiographic ejection fractions. Echocardiographic ejection fraction correlated...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197907000-00004
更新日期:1979-07-01 00:00:00
abstract::A 41-year-old man from South Asia presented with a several months' history of unilateral nasal obstruction and bleeding. At nasal endoscopy, two strawberry-like, friable, polypoid masses in the upper airways were detected. The patient's clinical trait was compatible with an infectious disease. F-FDG PET/MRI was perfor...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003138
更新日期:2020-10-01 00:00:00
abstract::The value of using heparin as a pharmacologic intervention to induce a positive scintiscan was studied in a patient with chronic occult gastrointestinal bleeding. When all standard diagnostic tests (upper and lower gastrointestinal series, upper and lower endoscopy, and conventional noninterventional Tc-99m RBC imagin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198404000-00003
更新日期:1984-04-01 00:00:00
abstract::Usefulness of N-isopropyl-p-I-123 iodoamphetamine (I-123 IMP) for the detection of malignant melanoma and malignant lymphoma is well known. The appropriate interval from administration until image acquisition is unusual because the accumulation mechanism is different. We present a case of choroidal melanoma of the rig...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3180a1abbd
更新日期:2007-08-01 00:00:00
abstract:AIM:The aim of the study was to evaluate if there is a prognostic importance of pretreatment Tc-MAA uptake of liver lesion of patients who received Y selective internal radiation therapy (SIRT) treatment for hepatocellular cancer (HCC) or not. METHODS:Nineteen patients (5 female and 14 male patients; mean age, 64.5 ± ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31828162e8
更新日期:2013-04-01 00:00:00
abstract::Thallium-201 uptake patterns in the orbits are not widely known. Diffuse, bilateral orbital localization of TI-201 chloride may be an incidental finding because of orbital muscle or other soft tissue uptake. Differences in orbital blood flow and soft tissue mass may be the cause of the varying uptake intensities in mo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199506000-00015
更新日期:1995-06-01 00:00:00
abstract:PURPOSE:To determine the yield and patterns of abnormalities noted by Tc-99m DMSA renal imaging in cases of first-time versus recurrent urinary tract infections (UTIs) in children. MATERIALS AND METHODS:We reviewed 101 Tc-99m DMSA studies performed for 52 first-time and 49 recurrent UTIs in 99 children during a period...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199912000-00004
更新日期:1999-12-01 00:00:00
abstract::Breast cancer is the most common cancer in women with rising incidence worldwide. F-FDG PET/CT imaging has already established itself as a pivotal modality for staging, restating and response assessment in patients with carcinoma breast. The complex biology of this cancer is increasingly being decoded and various mole...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002783
更新日期:2020-02-01 00:00:00
abstract::Various etiologies could cause focal I accumulation. Hepatic cyst is one of these etiologies. Here we present a 59-year-old man with a history of papillary thyroid cancer resection who received radioiodine therapy for three times. The images after the I therapy of the second and third time showed variable activity upt...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002442
更新日期:2019-04-01 00:00:00
abstract::Cerebral vascular lesions are integral to the diagnosis of vascular parkinsonism (VP). The VP, also referred to as lower body parkinsonism, is frequently caused by subcortical white matter lesions, but lesions at any levels of the nigro-striato-thalamo-cortical pathway can also cause VP, thus giving rise to various sy...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002721
更新日期:2019-11-01 00:00:00
abstract::A case of non-Hodgkin's lymphoma of the abdomen studied by gallium SPECT imaging is reported. The tomographic slices accurately demonstrated the location of residual disease after chemotherapy in the region of the transverse mesocolon. Previous transmission CT had shown considerable persistent retroperitoneal lymphade...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198605000-00014
更新日期:1986-05-01 00:00:00
abstract::Image-guided biopsy of prostate with multiparametric MRI is being adopted in the workup of prostate adenocarcinoma (PAC). Ga-PSMA PET/CT-guided biopsy has also been shown to be equally sensitive in the evaluation of higher-grade tumors with increased PSMA expression. The sensitivity of Ga-PSMA PET/CT, however, reduces...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003440
更新日期:2020-11-23 00:00:00
abstract::A patient is described with non-Hodgkin lymphoma and erythematous skin nodules suspected to be erythema nodosum. The patient underwent serial fluorodeoxyglucose (FDG) positron emission tomography (PET), which demonstrated normalization of FDG uptake by the lymphoma after 2 cycles of chemotherapy, but there was new abn...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.RLU.0000079389.14140.be
更新日期:2003-08-01 00:00:00
abstract::Metastatic pulmonary calcification (MPC) characterized by diffuse calcium deposition in the lungs is known to occur in patients with chronic renal failure. However, MPC with pulmonary artery calcification is uncommon and has only been detected in a few patients with severe disorders. A 48-year-old man with chronic ren...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000159672.35328.13
更新日期:2005-05-01 00:00:00
abstract::C-methionine (MET) positron emission tomography (PET) is more sensitive than F-fluorodeoxyglucose (FDG)-PET for detecting myeloma lesion. Many clinical studies support this evidence mainly for multiple myeloma cases of IgG or IgA subtypes. However, this is not confirmed for low monoclonal protein-producing myelomas, s...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001821
更新日期:2017-11-01 00:00:00
abstract:PURPOSE:To investigate whether the patterns of striatal dopamine depletion could provide prognostic information on the clinical profiles of early-stage Parkinson disease (PD). METHODS:Approximately 634 patients with drug-naive PD who underwent F-FP-CIT PET scans were followed up for at least 2 years. After quantifying...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002251
更新日期:2018-11-01 00:00:00
abstract::Dual radionuclide imaging of the neck (Tc-99m pertechnetate and TI-201 thallous chloride) was performed in 22 patients with chemical evidence of hyperparathyroidism (elevated blood calcium and parathormone [PTH] levels). Of these, 19 of 22 had localization of a TI-201 "excess" area on radiothallium-radiotechnetium sub...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198504000-00003
更新日期:1985-04-01 00:00:00
abstract::Pheochromocytomas/paragangliomas (PGLs) are rare tumors and mostly benign. We report on a 32-year-old woman with metastatic PGL who was first diagnosed with an abdominal PGL at the age of 12 years. She soon developed metastatic disease and received several treatments including external beam radiation and chemotherapy....
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001116
更新日期:2016-05-01 00:00:00
abstract::Focal nodular fat sparing of the liver may show, on PET/CT imaging, prominent tracer uptake over a background of less metabolic features of steatosis. This finding, already reported with F-FDG, may mimic primary or secondary neoplasms of the liver. The authors present an additional case of nodular fat-sparing hepatic ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002898
更新日期:2020-03-01 00:00:00
abstract:ABSTRACT:A 63-year-old man with recent diagnosis of high-risk prostate adenocarcinoma was referred to our Nuclear Medicine Department for 18F-fluciclovine PET/CT to rule out metastasis in the setting of elevated serum prostate-specific antigen levels. The patient had previous history of nodular melanoma of the right ch...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003319
更新日期:2021-02-01 00:00:00
abstract:PURPOSE:We investigated the value of early dynamic (ED) PET for the detection and characterization of bladder cancer. METHODS:Fifty-two bladder cancer patients were prospectively enrolled. The study protocol was composed of ED, whole-body (WB, 60 minutes after injection), and additional delayed (AD, 120 minutes after ...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/RLU.0000000000001780
更新日期:2017-10-01 00:00:00
abstract::Hairy cell leukemia is a rare hematologic malignancy characterized by splenomegaly, pancytopenia, and susceptibility to infections. We report a case of a 66-year-old man, diagnosed with hairy cell leukemia, without severe cytopenias and splenomegaly, but with an extensive pathological retroperitoneal mass and infiltra...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002557
更新日期:2019-07-01 00:00:00
abstract:PURPOSE:In recent years, several case reports have described venous thromboembolism (VTE) on FDG PET/CT. In this short communication, we present results from a proof-of-concept pilot study aimed at providing some preliminary data on the efficacy of FDG PET/CT in prospective patients with suspected VTE. PATIENTS AND ME...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000453
更新日期:2015-01-01 00:00:00