Coherent concepts are computed in the anterior temporal lobes.

Abstract:

:In his Philosophical Investigations, Wittgenstein famously noted that the formation of semantic representations requires more than a simple combination of verbal and nonverbal features to generate conceptually based similarities and differences. Classical and contemporary neuroscience has tended to focus upon how different neocortical regions contribute to conceptualization through the summation of modality-specific information. The additional yet critical step of computing coherent concepts has received little attention. Some computational models of semantic memory are able to generate such concepts by the addition of modality-invariant information coded in a multidimensional semantic space. By studying patients with semantic dementia, we demonstrate that this aspect of semantic memory becomes compromised following atrophy of the anterior temporal lobes and, as a result, the patients become increasingly influenced by superficial rather than conceptual similarities.

authors

Lambon Ralph MA,Sage K,Jones RW,Mayberry EJ

doi

10.1073/pnas.0907307107

subject

Has Abstract

pub_date

2010-02-09 00:00:00

pages

2717-22

issue

6

eissn

0027-8424

issn

1091-6490

pii

0907307107

journal_volume

107

pub_type

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