Abstract：
:The action of various manganese organic compounds, which are structural analogs of methylcyclopentadienyl manganese tricarbonyl (MMT), was investigated. Only the cyclopentadienyl manganese tricarbonyl compounds are effective inhibitors of mitochondrial respiration, but only when associated with NAD+-linked substrates. The manganese tricarbonyl group is required for this mitochondrial respiration inhibition. The substitutions operated on the cyclopentadienyl cycle also interfere and increase the inhibitory effect. Meanwhile, the benzoyl and thenoyl groups are more effective than the methyl group. The effects of the various compounds result from their special electronic configuration.
journal_name
Toxicologyjournal_title
Toxicologyauthors
Autissier N,Gautheron B,Dumas P,Brosseau J,Loireau Adoi
10.1016/0300-483x(77)90001-4subject
Has Abstractpub_date
1977-10-01 00:00:00pages
125-33issue
2eissn
0300-483Xissn
1879-3185pii
0300-483X(77)90001-4journal_volume
8pub_type
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