Abstract:
BACKGROUND:The aim of the pilot study was to assess the feasibility, efficacy, and accuracy of the sentinel lymph node biopsy (SLNB) procedure in vulvar cancer. PATIENTS AND METHODS:From February 2003 to March 2007, 17 patients with vulvar cancer, clinical Stages I and II, underwent SLN (sentinel lymph node) detection, followed by a complete inguinal-femoral lymphadenectomy. Demographic, surgical, and pathologic data on all patients were reviewed. RESULTS:17 patients underwent the SLNB procedure. Sixteen had vulvar carcinoma and one patient suffered from melanoma of the vulva. Midline localisation was done in 11 patients (64.7%). A total of 371 lymph nodes were resected. The median number of removed lymph nodes was 15 (range 2 to 81). Nineteen lymph nodes were positive with a maximum of six in one patient. Overall the detection rate for the sentinel lymph node was 88.2% (15 out of 17). One of the two patients with a non detectable sentinel node had positive lymph nodes. Eighty lymph nodes were detected as the sentinel node. The median number of sentinel nodes was five (range 0 to 11). Seventeen sentinel nodes were involved. The sentinel node was negative in nine patients; one of these had involved lymph nodes. CONCLUSIONS:SLNB is feasible and safe to perform in vulvar cancer. Further evaluation is needed until new guidelines allow the use in early-stage vulvar cancer.
journal_name
Eur J Gynaecol Oncoljournal_title
European journal of gynaecological oncologyauthors
Camara O,Gonnert H,Herrmann J,Egbe A,Diebolder H,Gajda M,Michels W,Runnebaum IBsubject
Has Abstractpub_date
2009-01-01 00:00:00pages
622-4issue
6eissn
0392-2936issn
2709-0086journal_volume
30pub_type
杂志文章abstract:BACKGROUND:The development of cancer from adenomyotic foci is a rare occurrence. The diagnosis is frequently delayed because of the absence of tumor in the eutopic endometrium. CASE REPORT:We present a case of a 64-year-old postmenopausal woman with irregular vaginal bleeding and dull abdominal pain. Hysteroscopy was ...
journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,评审
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章,meta分析
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
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doi:
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journal_title:European journal of gynaecological oncology
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
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journal_title:European journal of gynaecological oncology
pub_type: 杂志文章
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