Leukemia incidence among people exposed to chronic radiation from the contaminated Techa River, 1953-2005.

Abstract:

:Beginning in 1950, people living on the banks of the Techa River received chronic low-dose-rate internal and external radiation exposures as a result of releases from the Mayak nuclear weapons plutonium production facility in the Southern Urals region of the Russian Federation. The Techa River cohort includes about 30,000 people who resided in riverside villages sometime between 1950 and 1960. Cumulative red bone marrow doses range up to 2 Gy with a mean of 0.3 Gy and a median of 0.2 Gy. Between 1953 and 2005, 93 first primary cases of leukemia, including 23 cases of chronic lymphatic leukemia (CLL), were ascertained among the cohort members. A significant linear dose-response relationship was seen for leukemias other than CLL (P < 0.001), but not for CLL. The estimated excess relative risk per Gy is 4.9 (95% confidence interval (CI): 1.6; 14.3) for leukemias other than CLL and less than 0 (95% upper bound 1.4) for CLL.

journal_name

Radiat Environ Biophys

authors

Krestinina L,Preston DL,Davis FG,Epifanova S,Ostroumova E,Ron E,Akleyev A

doi

10.1007/s00411-009-0257-5

subject

Has Abstract

pub_date

2010-05-01 00:00:00

pages

195-201

issue

2

eissn

0301-634X

issn

1432-2099

journal_volume

49

pub_type

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