C3d immunohistochemistry on formalin-fixed tissue is a valuable tool in the diagnosis of bullous pemphigoid of the skin.

abstract：:Cutaneous syncytial myoepithelioma (CSM) is a recently recognized, histopathological variant of myoepithelial (ME) tumors of the skin. It is characterized by a syncytial arrangement of spindled, ovoid, and/or epithelioid cells forming a well-circumscribed, unencapsulated dermal nodule. There is a paucity of intervenin...

journal_title：Journal of cutaneous pathology

authors： MacKinnon WF,Carter MD,Bridge JA,Tremaine RD,Walsh NMG

更新日期：2019-06-01 00:00:00

abstract：:The distinction of metastatic carcinomas to the skin from poorly differentiated primary cutaneous carcinomas and sometimes primary benign adnexal tumors can pose a significant diagnostic challenge. The purpose of this study was to evaluate the role of p63 and podoplanin (D2-40) immunoreactivity for separating primary ...

journal_title：Journal of cutaneous pathology

authors： Plaza JA,Ortega PF,Stockman DL,Suster S

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Cutaneous epithelioid angiosarcoma is a type of cutaneous angiosarcoma and usually arise both on the head or neck of the elderly. CASE REPORT:An 86-year-old male with an epithelioid angiosarcoma of the scalp that mimicked malignant melanoma. RESULTS:A large irregular dark grey-blue plaque with an adjacent ...

journal_title：Journal of cutaneous pathology

authors： Brightman LA,Demierre MF,Byers HR

更新日期：2006-01-01 00:00:00

abstract：:The diagnosis of a CD30+ cutaneous infiltrate is often difficult and requires clinicopathologic correlation. To further evaluate this challenge, initial clinical and histopathologic diagnoses were correlated with final clinicopathologic diagnosis in 44 cases with CD30 immunopositivity. Dermatopathologic evaluation con...

journal_title：Journal of cutaneous pathology

authors： De Souza A,Carter JB,Harris NL,Ferry JA,Duncan LM

更新日期：2015-07-01 00:00:00

abstract：:Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive form of peripheral T-cell lymphoma, characterized by systemic symptoms, diffuse lymphadenopathy, hepatosplenomegaly and immunodysregulation. Half of AITL is associated with cutaneous symptoms, but only few cases with bullous eruption have been described. Assoc...

journal_title：Journal of cutaneous pathology

authors： Colmant C,Camboni A,Dekeuleneer V,Marot L,Dachelet C,Baeck M

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Rare cases of a non-bullous neutrophilic dermatosis occurring in patients with lupus erythematosus (LE) have been reported, often as the presenting manifestation of the disease. METHODS:We reviewed hematoxylin and eosin-stained slides and obtained clinical information from four additional patients, two of w...

journal_title：Journal of cutaneous pathology

authors： Gleason BC,Zembowicz A,Granter SR

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Langerhans' cells (CD1a positive, bone marrow-derived cells), are the antigen presenting cells of the skin. Our knowledge about the status of these cells in eczematous dermatitis is incomplete. AIM:This study tests the hypothesis that 'the development of eczematous dermatitis is associated with alterations ...

journal_title：Journal of cutaneous pathology

authors： Hussein MR

更新日期：2008-06-01 00:00:00

abstract：:Fifteen halo nevi were stained for the presence of S100 protein by an unlabelled antibody peroxidase-antiperoxidase method. S100 protein was clearly identifiable within nevus cell nests in the inflammatory infiltrate. The presence of this substance helped to identify nevus cells in dense inflammatory infiltrates and c...

journal_title：Journal of cutaneous pathology

authors： Penneys NS,Mayoral F,Barnhill R,Ziegels-Weissman J,Nadji M

更新日期：1985-02-01 00:00:00

abstract：:The authors have observed 15 examples of a distinctive fibrohistiocytic lesion in children and adolescents which they chose to designate as "atypical fibrous histiocytoma" (AFH). Patient ages ranged from 1 to 19 years (mean 9.3 yr.). Only two cases were encountered in the first year of life, but 7 were seen in childre...

journal_title：Journal of cutaneous pathology

authors： Marrogi AJ,Dehner LP,Coffin CM,Wick MR

更新日期：1992-08-01 00:00:00

abstract：:We report a case of a 68-year-old man with cutaneous leiomyosarcoma of the penis. Leiomyosarcoma of the penis is an extremely rare neoplasm that usually presents in middle to old age, and to our knowledge only approximately 30 cases have been reported in the literature to date. This is an important diagnosis in the di...

journal_title：Journal of cutaneous pathology

authors： Cibull TL,Thomas AB,Badve S,Billings SD

更新日期：2008-06-01 00:00:00

abstract：:The advent of immunoperoxidase technique on paraffin embedded tissue has identified a number of shared immunologic markers present in various lymphoproliferative cutaneous disorders. Two such disorders are the recently described primary cutaneous CD30-positive anaplastic large cell lymphoma (ALCL) and lymphomatoid pap...

journal_title：Journal of cutaneous pathology

authors： Tomaszewski MM,Lupton GP,Krishnan J,May DL

更新日期：1995-08-01 00:00:00

abstract：:A 1-month-old female infant was seen in consultation because of a congenital subcutaneous nodule, 2 x 3 cm in diameter, in the right retroauricular area. The nodule was surgically excised. Histologically, a large subcutaneous nodular mass was well delimited but not encapsulated. It consisted of a monomorphous sheet of...

journal_title：Journal of cutaneous pathology

authors： Sánchez Yus E,Requena L,Villegas C,Valle P

更新日期：1995-10-01 00:00:00

abstract：:A 34-year-old man with acquired immunodeficiency syndrome presented with multiple skin lesions clinically suggestive of molluscum contagiosum. Three skin biopsy specimens were obtained which showed dermal abscesses containing multiple gram-positive cocci admixed with granular necrotic dermal material. In 2, there were...

journal_title：Journal of cutaneous pathology

authors： Boudreau S,Hines HC,Hood AF

更新日期：1988-02-01 00:00:00

abstract：:The basal cell adhesion molecule (B-CAM) is a 90-kD cell surface glycoprotein with a characteristic immunoglobulin domain structure. The pattern of B-CAM expression in cultured cells suggests that the molecule is associated with a substrate-adherent growth pattern in some lineages. We investigated the expression of B-...

journal_title：Journal of cutaneous pathology

authors： Bernemann TM,Podda M,Wolter M,Boehncke WH

更新日期：2000-03-01 00:00:00

abstract：:Deep wrinkles of 6 elderly people were investigated using electron microscopy. There were ultrastructural differences in the elastotic changes between the area of the wrinkle and the surrounding areas. Elastic fibers containing electron-dense inclusions were mostly seen in the upper dermis of the wrinkled area and wer...

journal_title：Journal of cutaneous pathology

authors： Tsuji T

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:The use of immunohistochemical (IHC) stains in dermatopathology is commonplace; however, little is known regarding utilization trends in melanoma diagnosis. Current Medicare local coverage determinations (LCDs) state that most pigmented lesions, including melanoma, can be diagnosed using H&E alone. METHODS:...

journal_title：Journal of cutaneous pathology

authors： Dinehart MS,Dinehart SM,Sukpraprut-Braaten S,High WA

更新日期：2020-05-01 00:00:00

abstract：:Cutaneous mixed tumors (MTs), also known as chondroid syringomas, usually arise as small nodules in the head and neck region. We describe an unusual case of a giant MT measuring 9 cm in its greatest diameter, occurring as a slowly growing pedunculated mass on the breast of a 74-year-old woman. Although MT may rarely o...

journal_title：Journal of cutaneous pathology

authors： Magro G,Floridia F,Geraci G,Marino B

更新日期：2009-06-01 00:00:00

abstract：:We present the case of a 77-year-old male undergoing treatment for mycosis fungoides (MF) who presented for removal of an acrochordon on his mid back. Histopathologic examination of the acrochordon revealed a dense, band-like lymphocytic inflammatory infiltrate in the dermis with epidermotropism of single lymphocytes ...

journal_title：Journal of cutaneous pathology

authors： McClain CM,Cole MB,Robbins JB,Kantrow SM

更新日期：2012-12-01 00:00:00

abstract：:A 24-year-old black woman from Uganda was seen for treatment of multiple papules on her hands and feet. The lesions corresponded microscopically to foci of hyperkeratosis and acanthosis. Acid orcein stain revealed marked elastic fiber fragmentation. Acrokeratoelastoidosis of Costa (AKE) was diagnosed. The same damage ...

journal_title：Journal of cutaneous pathology

authors： Fiallo P,Pesce C,Brusasco A,Nunzi E

更新日期：1998-11-01 00:00:00

abstract：:Large cell neuroendocrine carcinoma (LCNEC) of the larynx is an aggressive form of neuroendocrine carcinoma that affects smokers at an average age of 60 years. LCNEC is characterized by large cells with round to ovoid nuclei distributed in a trabecular or nested growth pattern. Previously, laryngeal LCNEC and atypical...

journal_title：Journal of cutaneous pathology

authors： Dunn A,Broadfoot BG,Hunt J,Kaley JR,Atiq O,Gutta NB,Wang X,Gardner JM,Shalin SC

更新日期：2018-03-01 00:00:00

abstract：:CD44, a family of closely related glycoproteins generated by alternative splicing, as well as the increased beta 1,6-branching of Asn-linked oligosaccharides (beta 1,6-branches), have been implicated in tumor progression and metastasis. We have investigated the expression of CD44 standard (CD44s), various CD44 splice ...

journal_title：Journal of cutaneous pathology

authors： Seelentag WK,Böni R,Günthert U,Futo E,Burg G,Heitz PU,Roth J

更新日期：1997-04-01 00:00:00

abstract：:Verrucous hemangioma represents a rare congenital vascular proliferation that may be mistaken for angiokeratoma. Histopathological examination of a deep biopsy is necessary to confirm the diagnosis of verrucous hemangioma based on its involvement of the deep dermis and subcutaneous tissue. We present two cases of verr...

journal_title：Journal of cutaneous pathology

authors： Clairwood MQ,Bruckner AL,Dadras SS

更新日期：2011-09-01 00:00:00

abstract：:Long-term survivors of harlequin ichthyosis (HI) have raised a controversy over the differences between HI and lamellar ichthyosis (LI). Abnormal lamellar granules and the failure of conversion from profilaggrin to filaggrin have been reported in HI. On the other hand, malformation of the cornified cell envelope as a ...

journal_title：Journal of cutaneous pathology

authors： Akiyama M,Yoneda K,Kim SY,Koyama H,Shimizu H

更新日期：1996-12-01 00:00:00

abstract：:The characteristic histologic change seen at 2 h in the Rumpel-Leede (Hess) test is, in addition to focal hemorrhage in the upper dermis, a perivascular lymphocyte infiltrate with focal areas of lymphocytic epidermal invasion. The histologic findings, even with the liquefaction degeneration, are similar to those of pu...

journal_title：Journal of cutaneous pathology

authors： Duncan SC,Winkelmann RK

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:The diagnosis of 'cellular dermal nodule in melanocytic nevi' is challenging, as it can simulate invasive and tumorigenic melanoma. Because cellular nodules are presumed benign, it is essential to differentiate them from true malignant melanoma arising within a nevus, which portends a poor prognosis. Althoug...

journal_title：Journal of cutaneous pathology

authors： Xu X,Bellucci KS,Elenitsas R,Elder DE

更新日期：2004-02-01 00:00:00

abstract：:The term hemangioendothelioma has been used in recent years to name a heterogeneous group of vascular neoplasms, intermediate in both biological behavior and histopathologic appearance between benign tumors (hemangiomas) and frankly malignant tumors (angiosarcomas). Thus, within the spectrum of hemangioendothelioma ha...

journal_title：Journal of cutaneous pathology

authors： Requena L,Luis Díaz J,Manzarbeitia F,Carrillo R,Fernández-Herrera J,Kutzner H

更新日期：2008-02-01 00:00:00

abstract：:Penicillamine-induced cutaneous elastosis perforans serpiginosa associated with a large air-cyst in the right lung is described in a 29-year-old female patient with Wilson disease. Identical light and electron-microscopic changes were present in both dermal and pulmonary elastic tissue, suggesting a disseminated drug-...

journal_title：Journal of cutaneous pathology

authors： Bardach H,Gebhart W,Niebauer G

更新日期：1979-08-01 00:00:00

abstract：:Langerhans' cell histiocytosis (LCH) may be associated with a wide range of neoplastic disorders. However, the combination of a LCH and a basal cell carcinoma (BCC) of the skin still represents a highly unusual condition. In this publication, we report the case of a 48-year-old woman who developed a localized LCH invo...

journal_title：Journal of cutaneous pathology

authors： Simonart T,Urbain F,Verdebout JM,Feoli F,Lespagnard L,Dargent JL

更新日期：2000-10-01 00:00:00

abstract：:Cell adhesion between surfaces of cells and to extracellular matrices represents a fundamental mechanism in tissue organization and influences the biological behaviour and the architecture of tumors. We investigated the expression of various adhesion molecules in normal skin (n=5), nevi (n=29), and malignant melanoma ...

journal_title：Journal of cutaneous pathology

authors： Tronnier M,Alexander M,Wolff HH

更新日期：1997-05-01 00:00:00

abstract：:We report 2 cases of congenital porokeratotic eccrine nevus in a 5-year-old girl and a 7-year-old boy. The clinical manifestations were those of nevus comedonicus palmaris. The histologic picture consisted of comedo-like dilatations and cornoid lamellae involving the eccrine ostia and ducts. One of the cases showed an...

journal_title：Journal of cutaneous pathology

authors： Moreno A,Pujol RM,Salvatella N,Alomar A,de Moragas JM

更新日期：1988-02-01 00:00:00