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Tolerance of sunitinib in dialyzed patients with metastatic renal cell carcinoma.

Abstract：

:The use of sunitinib in dialysis patients is poorly described but is of clinical importance. We report 2 cases of patients receiving sunitinib for metastatic renal cell carcinoma while undergoing dialysis. The first patient is undergoing hemodialysis and, though responding to sunitinib, is having significant fatigue and hypertension. The second patient underwent peritoneal dialysis and also had significant problems with hypertension. The tolerance of sunitinib in the setting of dialysis can be challenging as these interventions can have synergistic side effects. Close monitoring for toxicity and dosage manipulations might be required if such therapy is attempted.

journal_name

Clin Genitourin Cancer

journal_title

Clinical genitourinary cancer

authors

Vickers MM,Heng DY,Hemmelgarn B,Eigl BJ

doi

10.3816/CGC.2009.n.035

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

E104-6

issue

3

eissn

1558-7673

issn

1938-0682

pii

S1558-7673(11)70042-8

journal_volume

7

pub_type

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