Abstract:
:Francisella tularensis is a highly virulent bacterial species that causes various forms of tularemia in humans. The urgency in understanding the pathogenesis of these diseases has stimulated unprecedented interest in this bacterial species over the past few years. Recent findings underscore a number of important distinctions between the Francisella ssp. and emphasize the importance of using type A F. tularensis strains when characterizing pathophysiological responses that are relevant to the lethal forms of human disease. This review focuses on the mediators of cell death induction in infected tissues and the implications of these processes on the pathophysiological changes observed in various host species.
journal_name
FEMS Microbiol Lettjournal_title
FEMS microbiology lettersauthors
Parmely MJ,Fischer JL,Pinson DMdoi
10.1111/j.1574-6968.2009.01791.xsubject
Has Abstractpub_date
2009-11-01 00:00:00pages
1-11issue
1eissn
0378-1097issn
1574-6968pii
FML1791journal_volume
301pub_type
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