Cellular localization of somatostatin mRNA in rat retina.

Abstract:

:In an attempt to determine the localization of the messenger RNA (mRNA) encoding somatostatin in the rat retina, we studied Sprague-Dawley rats by in situ hybridization histochemistry using radiolabelled oligodeoxyribonucleotides complementary for rat somatostatin mRNA. Among the layers of retina, we found specific labelling in the soma of some cells in the innermost and outermost laminae of the inner nuclear layer and in the ganglion cell layer; no specific labelling was observed in the inner and outer plexiform layers or in the outer nuclear layer. These data indicate the major site of somatostain synthesis within the rat retina.

journal_name

Neuropeptides

journal_title

Neuropeptides

authors

Yamaguchi K,Gaur VP,Spira AW,Turner JE

doi

10.1016/0143-4179(90)90135-l

subject

Has Abstract

pub_date

1990-09-01 00:00:00

pages

13-6

issue

1

eissn

0143-4179

issn

1532-2785

pii

0143-4179(90)90135-L

journal_volume

17

pub_type

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