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Genomic privacy and limits of individual detection in a pool.

Abstract：

:Recent studies have demonstrated that statistical methods can be used to detect the presence of a single individual within a study group based on summary data reported from genome-wide association studies (GWAS). We present an analytical and empirical study of the statistical power of such methods. We thereby aim to provide quantitative guidelines for researchers wishing to make a limited number of SNPs available publicly without compromising subjects' privacy.

journal_name

Nat Genet

journal_title

Nature genetics

authors

Sankararaman S,Obozinski G,Jordan MI,Halperin E

doi

10.1038/ng.436

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

965-7

issue

9

eissn

1061-4036

issn

1546-1718

pii

ng.436

journal_volume

41

pub_type

杂志文章

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