Chronic inflammatory disease, lymphoid tissue neogenesis and extranodal marginal zone B-cell lymphomas.

Abstract:

:Chronic autoimmune or pathogen-induced immune reactions resulting in lymphoid neogenesis are associated with development of malignant lymphomas, mostly extranodal marginal zone B-cell lymphomas (MZBCLs). In this review we address (i) chemokines and adhesion molecules involved in lymphoid neogenesis; (ii) the autoimmune diseases and pathogens which are associated with development of B-cell lymphomas; (iii) the molecular mechanisms involved in the initiation and progression of MZBCL; and (iv) 'potential' mouse models for MZBCL.

journal_name

Haematologica

journal_title

Haematologica

authors

Bende RJ,van Maldegem F,van Noesel CJ

doi

10.3324/haematol.2009.005983

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

1109-23

issue

8

eissn

0390-6078

issn

1592-8721

pii

haematol.2009.005983

journal_volume

94

pub_type

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