Ethanol sclerotherapy: a treatment option for ovarian endometriomas before ovarian stimulation.

Abstract:

:Several surgical treatment modalities have been described in cases of isolated or multiple ovarian endometriotic cysts. The aim of this preliminary study was to investigate and test the efficacy of ethanol sclerotherapy (EST) for recurrent endometriotic cysts, before ovarian stimulation in infertile patients with an adequate ovarian status. In the setting of a prospective comparative study, EST was proposed to 31 infertile patients with recurrence of ovarian endometriomas before inclusion in assisted reproduction cycles. Reproductive outcome was compared with that of patients who had previous laparoscopic cystectomy for recurrent endometriomas. The mean size of endometriomas treated with sclerotherapy was 38.6 +/- 11.2 mm in diameter. Ovarian cysts recurred in 12.9% of cases; at a mean time of 10 months after EST. Ovarian reserve and ovarian response to stimulation were better in the EST group than in the control group. Consequently, clinical and cumulative pregnancy rates of the study group were higher than those of the control group (48.3% versus 19.2%, P = 0.04; and 55.2% versus 26.9%, P = 0.03, respectively). Ethanol sclerotherapy may be a good alternative to surgical management of recurrent endometriotic cysts before assisted reproductive treatment. It could be advised for selected infertile patients.

journal_name

Reprod Biomed Online

authors

Yazbeck C,Madelenat P,Ayel JP,Jacquesson L,Bontoux LM,Solal P,Hazout A

doi

10.1016/s1472-6483(10)60055-7

subject

Has Abstract

pub_date

2009-07-01 00:00:00

pages

121-5

issue

1

eissn

1472-6483

issn

1472-6491

pii

S1472-6483(10)60055-7

journal_volume

19

pub_type

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