Abstract:
:An increasingly pervasive environment of reduced activity and easy access to high caloric food is leading to an epidemic of poor cardiovascular fitness, obesity, insulin resistance and type 2 diabetes (T2DM) in children. Studies have shown that insulin resistance (IR) to be an independent predictor for morbidity as well as mortality. These serve as a strong stimulus for public health strategies to improve fitness in children and adolescents. Methods to assess IR, improve IR and understand complications are increasingly important in children.
journal_name
Rev Endocr Metab Disordjournal_title
Reviews in endocrine & metabolic disordersauthors
Carrel AL,Allen DBdoi
10.1007/s11154-009-9109-5subject
Has Abstractpub_date
2009-09-01 00:00:00pages
189-96issue
3eissn
1389-9155issn
1573-2606journal_volume
10pub_type
杂志文章,评审abstract::The carcinoid as originally described is part of the relatively large family of neuroendocrine neoplasia found in almost every organ. Historical reasons back their current definitions. Neuroendocrine cancer is most frequently observed in the lung and the digestive tract. In the lung is defined as carcinoid (typical an...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-017-9428-x
更新日期:2017-12-01 00:00:00
abstract::The vascular endothelium has been identified as an important component in diabetes-associated complications, which include many cardiovascular disorders such as atherosclerosis, hypertension and peripheral neuropathy. Additionally, insulin's actions on the endothelium are now seen as a major factor in the metabolic ef...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
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更新日期:2013-03-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-013-9256-6
更新日期:2014-06-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-011-9170-8
更新日期:2011-09-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-015-9309-0
更新日期:2015-03-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-016-9360-5
更新日期:2016-06-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
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更新日期:2010-06-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-007-9038-0
更新日期:2007-09-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-014-9302-z
更新日期:2015-03-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-012-9215-7
更新日期:2012-06-01 00:00:00
abstract::Vitamin D deficiency is highly prevalent among children and adolescents worldwide. The high rates of vitamin D deficiency during childhood are of major public health relevance, given the growing evidence that vitamin D deficiency may play a key role in the pathophysiology of many chronic diseases beyond rickets, inclu...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-007-9072-y
更新日期:2008-06-01 00:00:00
abstract::Obstructive sleep apnea (OSA) is a common disorder associated with cardiovascular disease (CVD). One theory to explain this relationship proposes that OSA can induce systemic inflammation, thereby inducing CVD. This theory is based on the premise that obesity is a pro-inflammatory state, and that physiological derange...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-014-9304-x
更新日期:2015-03-01 00:00:00
abstract::Celiac disease is a chronic enteropathy caused by permanent intolerance to gluten and similar proteins found in wheat, barley and rye. The intestinal mucosa of susceptible individuals is crossed by undigested gluten, which leads to a marked inflammatory response. The clinical features may vary from overt intestinal sy...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-007-9069-6
更新日期:2008-06-01 00:00:00
abstract::The last decade has been characterized by an intense research on the composition of the gut microbiome and the links with human health. While previous work was focused on the effects of prebiotics and probiotics, nowadays several laboratories are describing the gut microbiome and its metabolic functions. Gut microbiom...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-019-09533-9
更新日期:2019-12-01 00:00:00
abstract::The skeletal muscle is one of the major target organs of insulin and plays an essential role in insulin-induced glucose uptake. Some evidence indicates that insulin delivery to skeletal muscle interstitium through the endothelial cells is the rate-limiting step in insulin-stimulated glucose uptake. Researchers have al...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-013-9242-z
更新日期:2013-06-01 00:00:00
abstract::Weight gain at the outset of prolactinomas in many women is well documented. Yet, this symptom is absent from the clinical descriptions of the disease in textbooks and reviews. This omission is almost certainly due to the absence of a physiological explanation for the phenomenon, as prolactin is not a recognized fat p...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-019-09503-1
更新日期:2019-06-01 00:00:00
abstract::Intrauterine growth retardation (IUGR) has been linked to later development of type 2 diabetes in adulthood. Human studies indicate that individuals who were growth retarded at birth have impaired insulin secretion and insulin resistance. Multiple animal models of IUGR demonstrate impaired beta-cell function and devel...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-007-9045-1
更新日期:2007-06-01 00:00:00
abstract::Endothelial dysfunction associated with diabetes and cardiovascular disease is characterized by changes in vasoregulation, enhanced generation of reactive oxygen intermediates, inflammatory activation, and altered barrier function. These endothelial alterations contribute to excess cardiovascular disease in diabetes, ...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-013-9239-7
更新日期:2013-03-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-008-9076-2
更新日期:2008-06-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-012-9228-2
更新日期:2012-12-01 00:00:00
abstract::The hypothalamic pituitary adrenal (HPA) axis is the most common of the endocrine lines/axis' to be affected by HIV infection. There are multiple factors that contribute to this HPA axis dysregulation. Direct invasion of the various organs in the axis can be either by opportunistic infections or infiltrative diseases....
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-013-9244-x
更新日期:2013-06-01 00:00:00
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journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-016-9348-1
更新日期:2016-03-01 00:00:00
abstract::Prediabetes is a heterogeneous term that encompasses different origins of insulin resistance and insulin secretion that contribute to distinct patterns of hyperglycemia. In fact, prediabetes is an umbrella term that characterizes individuals at high risk for developing type 2 diabetes (T2D) and/or cardiovascular disea...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-016-9352-5
更新日期:2016-03-01 00:00:00
abstract::Worldwide prevalence of diabetes mellitus in the adult population is increasing and when explicitly searched within specific groups of patients, as those presenting cardiovascular disease (CVD), dysglycaemia is detected in about three-quarters of the patients. Dysglycaemia alone is a major risk factor for microvascula...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-010-9136-2
更新日期:2010-03-01 00:00:00
abstract::The adult endocrinologist may be asked to consult on a patient for unexplained biochemical disturbances that could be caused by an underlying inborn error of metabolism. A genetic disorder is generally less likely to be the cause as these disorders are individually rare, however inborn errors of metabolism are collect...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-018-9444-5
更新日期:2018-03-01 00:00:00
abstract::Impulsivity and compulsivity are multidimensional constructs that are increasingly considered determinants of obesity. Studies using functional magnetic resonance imaging (fMRI) have provided insight on how differences in brain response during tasks exploring facets of impulsivity and compulsivity relate to the ingest...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-019-09515-x
更新日期:2019-09-01 00:00:00
abstract::New insights on the high prevalence of functional decompensation of the thyroid among newborn and children from several states of India as well as neighbouring countries of Nepal and Bhutan helped to prevent nutritional iodine deficiency and iodine deficiency disorders through country-wide iodized salt prophylaxis. Pr...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-008-9094-0
更新日期:2008-09-01 00:00:00
abstract::The term "HCV syndrome" encompasses several organ- and systemic pathophysiological states, which often recognize autoimmunity or neoplastic evolution in their pathophysiology, as well as chronic HCV infection as trigger. The clinical features of HCV patients are heterogenous, and may include endocrine or metabolic dis...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-018-9475-y
更新日期:2018-12-01 00:00:00
abstract::An emerging branch of research is examining the linkage between Vitamin D and nonskeletal disorders, including endocrine diseases. In this regard, a still little studied aspect concerns the involvement of vitamin D in adrenal gland disorders. Adrenal gland disorders, which might be theoretically affected by vitamin D ...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-016-9391-y
更新日期:2017-09-01 00:00:00
abstract::It is widely acknowledged that compliance and persistence with oral osteoporosis medications, particularly with bisphosphonates, is poor. Several excellent reviews have been written on compliance and persistence with osteoporosis medications and have discussed improvements seen with extended dosing intervals. This rev...
journal_title:Reviews in endocrine & metabolic disorders
pub_type: 杂志文章,评审
doi:10.1007/s11154-010-9138-0
更新日期:2010-12-01 00:00:00