How to polymerize in order to survive.

Abstract:

:Perforation of membranes and pore formation is mediated by polymerization of proteins of the immune system, complement C9 and Perforin, which share the conserved MACPF domain. In this issue of Immunity, Baran et al. (2009) identify the molecular mechanism initiating polymerization as charge interactions in the MACPF domain.

journal_name

Immunity

journal_title

Immunity

authors

Podack ER

doi

10.1016/j.immuni.2009.04.004

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

668-70

issue

5

eissn

1074-7613

issn

1097-4180

pii

S1074-7613(09)00190-3

journal_volume

30

pub_type

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