Abstract:
:Perforation of membranes and pore formation is mediated by polymerization of proteins of the immune system, complement C9 and Perforin, which share the conserved MACPF domain. In this issue of Immunity, Baran et al. (2009) identify the molecular mechanism initiating polymerization as charge interactions in the MACPF domain.
journal_name
Immunityjournal_title
Immunityauthors
Podack ERdoi
10.1016/j.immuni.2009.04.004subject
Has Abstractpub_date
2009-05-01 00:00:00pages
668-70issue
5eissn
1074-7613issn
1097-4180pii
S1074-7613(09)00190-3journal_volume
30pub_type
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