ERP responses differentiate inverted but not upright face processing in adults with ASD.

Abstract:

:Individuals with autism spectrum disorders (ASD) have documented deficits in face processing, face memory and abnormal activation of the neural circuitry that supports these functions. To examine speed of processing of faces in ASD, high density event-related brain potentials were recorded to images of faces, inverted faces and non-face objects from 32 high-functioning adults with ASD and controls. Participants were instructed to focus on a cross hair prior to stimulus onset; the cross-hair location directed the participant's eye gaze to the eye region at stimulus onset. Although the ASD group preformed more poorly on behavioral tests of face and object memory, both groups demonstrated similar ERP responses, characterized by greater (positive) P1 and (negative) N170 amplitude to faces vs houses. N170 speed of processing to faces did not differ between groups. However, only the control group demonstrated differential responses to upright vs inverted faces. For the ASD group, the differential response to inverted vs upright faces was associated with better performance on face memory and self-reported social skills. It is possible that the use of attention cues may facilitate face processing in high-functioning adults with ASD, suggesting that the underlying neural circuitry can be activated in adults with ASD under specific demands.

authors

Webb SJ,Merkle K,Murias M,Richards T,Aylward E,Dawson G

doi

10.1093/scan/nsp002

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

578-87

issue

5

eissn

1749-5016

issn

1749-5024

pii

nsp002

journal_volume

7

pub_type

杂志文章
  • When is giving an impulse? An ERP investigation of intuitive prosocial behavior.

    abstract::Human prosociality is often assumed to emerge from exerting reflective control over initial, selfish impulses. However, recent findings suggest that prosocial actions can also stem from processes that are fast, automatic and intuitive. Here, we attempt to clarify when prosocial behavior may be intuitive by examining p...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsv077

    authors: Carlson RW,Aknin LB,Liotti M

    更新日期:2016-07-01 00:00:00

  • Asymmetric frontal cortical activity and negative affective responses to ostracism.

    abstract::Ostracism arouses negative affect. However, little is known about variables that influence the intensity of these negative affective responses. Two studies fill this void by incorporating work on approach- and withdrawal-related emotional states and their associated cortical activations. Study 1 found that following o...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsq027

    authors: Peterson CK,Gravens LC,Harmon-Jones E

    更新日期:2011-06-01 00:00:00

  • Is moral beauty different from facial beauty? Evidence from an fMRI study.

    abstract::Is moral beauty different from facial beauty? Two functional magnetic resonance imaging experiments were performed to answer this question. Experiment 1 investigated the network of moral aesthetic judgments and facial aesthetic judgments. Participants performed aesthetic judgments and gender judgments on both faces an...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsu123

    authors: Wang T,Mo L,Mo C,Tan LH,Cant JS,Zhong L,Cupchik G

    更新日期:2015-06-01 00:00:00

  • Foraging Optimally in Social Neuroscience: Computations and Methodological considerations.

    abstract::Research in social neuroscience has increasingly begun to use the tools of computational neuroscience to better understand behaviour. Such approaches have proven fruitful for probing underlying neural mechanisms. However, little attention has been paid to how the structure of experimental tasks relates to real-world d...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsaa037

    authors: Gabay AS,Apps MAJ

    更新日期:2020-03-30 00:00:00

  • Neural substrates for anticipation and consumption of social and monetary incentives in depression.

    abstract::Depression has been reliably associated with abnormalities in the neural representation of reward and loss. However, most studies have focused on monetary incentives; fewer studies have considered neural representation of social incentives. A direct comparison of non-social and social incentives within the same study ...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsz061

    authors: He Z,Zhang D,Muhlert N,Elliott R

    更新日期:2019-08-31 00:00:00

  • Putting our heads together: interpersonal neural synchronization as a biological mechanism for shared intentionality.

    abstract::Shared intentionality, or collaborative interactions in which individuals have a shared goal and must coordinate their efforts, is a core component of human interaction. However, the biological bases of shared intentionality and, specifically, the processes by which the brain adjusts to the sharing of common goals, re...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsy060

    authors: Fishburn FA,Murty VP,Hlutkowsky CO,MacGillivray CE,Bemis LM,Murphy ME,Huppert TJ,Perlman SB

    更新日期:2018-09-05 00:00:00

  • Developmental effects of aggressive behavior in male adolescents assessed with structural and functional brain imaging.

    abstract::Aggressive behavior is common during adolescence. Although aggression-related functional changes in the ventromedial prefrontal cortex (vmPFC) and frontopolar cortex (FPC) have been reported in adults, the neural correlates of aggressive behavior in adolescents, particularly in the context of structural neurodevelopme...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsp036

    authors: Strenziok M,Krueger F,Heinecke A,Lenroot RK,Knutson KM,van der Meer E,Grafman J

    更新日期:2011-01-01 00:00:00

  • Social anxiety modulates amygdala activation during social conditioning.

    abstract::Aversive social learning experiences might play a significant role in the aetiology of social anxiety disorder. Therefore, we investigated emotional learning and unlearning processes in healthy humans using a social conditioning paradigm. Forty-nine healthy subjects participated in a 2-day fMRI differential conditioni...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsr095

    authors: Pejic T,Hermann A,Vaitl D,Stark R

    更新日期:2013-03-01 00:00:00

  • Repetitive transcranial magnetic stimulation modulates the impact of a negative mood induction.

    abstract::High frequency repetitive Transcranial Magnetic Stimulation (rTMS) over the left dorsolateral prefrontal cortex (DLPFC) has been found to alleviate depressive symptoms. However, the mechanisms driving these effects are still poorly understood. In the current study, we tested the idea that this intervention protects ag...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章,随机对照试验

    doi:10.1093/scan/nsw180

    authors: Möbius M,Lacomblé L,Meyer T,Schutter DJLG,Gielkens T,Becker ES,Tendolkar I,van Eijndhoven P

    更新日期:2017-04-01 00:00:00

  • Death on the brain: effects of mortality salience on the neural correlates of ingroup and outgroup categorization.

    abstract::Research has shown that thoughts of one's; own death (i.e. mortality salience; MS) increase aspects of intergroup bias. However, the extent to which MS influences neural activity underlying basic person perception processes has not been examined. In the current study, event-related brain potentials were used as measur...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsp041

    authors: Henry EA,Bartholow BD,Arndt J

    更新日期:2010-03-01 00:00:00

  • The association between the 5-HTTLPR and neural correlates of fear conditioning and connectivity.

    abstract::Strong evidence links the 5-HTTLPR genotype to the modulation of amygdala reactivity during fear conditioning, which is considered to convey the increased vulnerability for anxiety disorders in s-allele carriers. In addition to amygdala reactivity, the 5-HTTLPR has been shown to be related to alterations in structural...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsu108

    authors: Klucken T,Schweckendiek J,Blecker C,Walter B,Kuepper Y,Hennig J,Stark R

    更新日期:2015-05-01 00:00:00

  • Hypoactive medial prefrontal cortex functioning in adults reporting childhood emotional maltreatment.

    abstract::Childhood emotional maltreatment (CEM) has adverse effects on medial prefrontal cortex (mPFC) morphology, a structure that is crucial for cognitive functioning and (emotional) memory and which modulates the limbic system. In addition, CEM has been linked to amygdala hyperactivity during emotional face processing. Howe...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsu008

    authors: van Harmelen AL,van Tol MJ,Dalgleish T,van der Wee NJ,Veltman DJ,Aleman A,Spinhoven P,Penninx BW,Elzinga BM

    更新日期:2014-12-01 00:00:00

  • Neural correlates of effective and ineffective mood induction.

    abstract::Emotional reactivity and the ability to modulate an emotional state, which are important factors for psychological well-being, are often dysregulated in psychiatric disorders. Neural correlates of emotional states have mostly been studied at the group level, thereby neglecting individual differences in the intensity o...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nst055

    authors: Kohn N,Falkenberg I,Kellermann T,Eickhoff SB,Gur RC,Habel U

    更新日期:2014-06-01 00:00:00

  • Effect of direct eye contact in PTSD related to interpersonal trauma: an fMRI study of activation of an innate alarm system.

    abstract::In healthy individuals, direct eye contact initially leads to activation of a fast subcortical pathway, which then modulates a cortical route eliciting social cognitive processes. The aim of this study was to gain insight into the neurobiological effects of direct eye-to-eye contact using a virtual reality paradigm in...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nss105

    authors: Steuwe C,Daniels JK,Frewen PA,Densmore M,Pannasch S,Beblo T,Reiss J,Lanius RA

    更新日期:2014-01-01 00:00:00

  • Impaired inhibitory control in anorexia nervosa elicited by physical activity stimuli.

    abstract::Besides food restriction, hyperactivity is considered a key behavioral trait of anorexia nervosa (AN), playing a major role in the pathogenesis and progression of the disorder. However, the underlying neurophysiology remains poorly understood. We used functional magnetic resonance imaging during two affective go/no-go...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nst070

    authors: Kullmann S,Giel KE,Hu X,Bischoff SC,Teufel M,Thiel A,Zipfel S,Preissl H

    更新日期:2014-07-01 00:00:00

  • Cool, callous and in control: superior inhibitory control in frequent players of video games with violent content.

    abstract::Research on the effects of media violence exposure has shown robust associations among violent media exposure, increased aggressive behavior, and decreased empathy. Preliminary research indicates that frequent players of violent video games may have differences in emotional and cognitive processes compared to infreque...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsx115

    authors: Stockdale L,Morrison RG,Palumbo R,Garbarino J,Silton RL

    更新日期:2017-12-01 00:00:00

  • Add a picture for suspense: neural correlates of the interaction between language and visual information in the perception of fear.

    abstract::We investigated how visual and linguistic information interact in the perception of emotion. We borrowed a phenomenon from film theory which states that presentation of an as such neutral visual scene intensifies the percept of fear or suspense induced by a different channel of information, such as language. Our main ...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsq050

    authors: Willems RM,Clevis K,Hagoort P

    更新日期:2011-09-01 00:00:00

  • Functional connectivity of the right inferior frontal gyrus and orbitofrontal cortex in depression.

    abstract::The orbitofrontal cortex extends into the laterally adjacent inferior frontal gyrus. We analyzed how voxel-level functional connectivity of the inferior frontal gyrus and orbitofrontal cortex is related to depression in 282 people with major depressive disorder (125 were unmedicated) and 254 controls, using FDR correc...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsaa014

    authors: Rolls ET,Cheng W,Du J,Wei D,Qiu J,Dai D,Zhou Q,Xie P,Feng J

    更新日期:2020-01-30 00:00:00

  • The functional role of ventral anterior cingulate cortex in social evaluation: disentangling valence from subjectively rewarding opportunities.

    abstract::Despite robust associations between the ventral anterior cingulate cortex (vACC) and social evaluation, the role of vACC in social evaluation remains poorly understood. Two hypotheses have emerged from existing research: detection of positive valence and detection of opportunities for subjective reward. It has been di...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsx132

    authors: Rigney AE,Koski JE,Beer JS

    更新日期:2018-01-01 00:00:00

  • Autism is characterized by dorsal anterior cingulate hyperactivation during social target detection.

    abstract::Though the functional neural correlates of impaired cognitive control and social dysfunction in autism spectrum disorders (ASD) have been delineated, brain regions implicated in poor cognitive control of social information is a novel area of autism research. We recently reported in a non-clinical sample that detection...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsp017

    authors: Dichter GS,Felder JN,Bodfish JW

    更新日期:2009-09-01 00:00:00

  • Culture-related differences in default network activity during visuo-spatial judgments.

    abstract::Studies on culture-related differences in cognition have shown that Westerners attend more to object-related information, whereas East Asians attend more to contextual information. Neural correlates of these different culture-related visual processing styles have been reported in the ventral-visual and fronto-parietal...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsr077

    authors: Goh JO,Hebrank AC,Sutton BP,Chee MW,Sim SK,Park DC

    更新日期:2013-02-01 00:00:00

  • Online processing of moral transgressions: ERP evidence for spontaneous evaluation.

    abstract::Experimental studies using fictional moral dilemmas indicate that both automatic emotional processes and controlled cognitive processes contribute to moral judgments. However, not much is known about how people process socio-normative violations that are more common to their everyday life nor the time-course of these ...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsu151

    authors: Leuthold H,Kunkel A,Mackenzie IG,Filik R

    更新日期:2015-08-01 00:00:00

  • The rTPJ's overarching cognitive function in networks for attention and theory of mind.

    abstract::Cortical networks underpinning attentional control and mentalizing converge at the right temporoparietal junction (rTPJ). It is debated whether the rTPJ is fractionated in neighboring, but separate functional modules underpinning attentional control and mentalizing, or whether one overarching cognitive mechanism expla...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsw163

    authors: Schuwerk T,Schurz M,Müller F,Rupprecht R,Sommer M

    更新日期:2017-01-01 00:00:00

  • An objective neural signature of rapid perspective taking.

    abstract::The frequency-tagging approach has generally been confined to study low-level sensory processes and always found related activation over the occipital region. Here for the first time, we investigated with it, high-level socio-cognitive functions, i.e. the processing of what other people are looking at which is referre...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsx135

    authors: Beck AA,Rossion B,Samson D

    更新日期:2018-01-01 00:00:00

  • The neural basis of intuitive and counterintuitive moral judgment.

    abstract::Neuroimaging studies on moral decision-making have thus far largely focused on differences between moral judgments with opposing utilitarian (well-being maximizing) and deontological (duty-based) content. However, these studies have investigated moral dilemmas involving extreme situations, and did not control for two ...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsr005

    authors: Kahane G,Wiech K,Shackel N,Farias M,Savulescu J,Tracey I

    更新日期:2012-04-01 00:00:00

  • Sustained happiness? Lack of repetition suppression in right-ventral visual cortex for happy faces.

    abstract::Emotional stimuli have been shown to preferentially engage initial attention but their sustained effects on neural processing remain largely unknown. The present study evaluated whether emotional faces engage sustained neural processing by examining the attenuation of neural repetition suppression to repeated emotiona...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsq058

    authors: Suzuki A,Goh JO,Hebrank A,Sutton BP,Jenkins L,Flicker BA,Park DC

    更新日期:2011-09-01 00:00:00

  • Intensity of affective experience is modulated by magnitude of intracranial electrical stimulation in human orbitofrontal, cingulate and insular cortices.

    abstract::The subjective and behavioral effects of intracranial electrical stimulation (iES) have been studied for decades, but there is a knowledge gap regarding the relationship between the magnitude of electric current and the type, intensity and valence of evoked subjective experiences. We report on rare iES data from 18 ne...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsz015

    authors: Yih J,Beam DE,Fox KCR,Parvizi J

    更新日期:2019-05-17 00:00:00

  • Mismatch or allostatic load? Timing of life adversity differentially shapes gray matter volume and anxious temperament.

    abstract::Traditionally, adversity was defined as the accumulation of environmental events (allostatic load). Recently however, a mismatch between the early and the later (adult) environment (mismatch) has been hypothesized to be critical for disease development, a hypothesis that has not yet been tested explicitly in humans. W...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsv137

    authors: Kuhn M,Scharfenort R,Schümann D,Schiele MA,Münsterkötter AL,Deckert J,Domschke K,Haaker J,Kalisch R,Pauli P,Reif A,Romanos M,Zwanzger P,Lonsdorf TB

    更新日期:2016-04-01 00:00:00

  • Behavioral and neuronal determinants of negative reciprocity in the ultimatum game.

    abstract::The rejection of unfair offers in the ultimatum game (UG) indicates negative reciprocity. The model of strong reciprocity claims that negative reciprocity reflects prosociality because the rejecting individual is sacrificing resources in order to punish unfair behavior. However, a recent study found that the rejection...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsw069

    authors: Kaltwasser L,Hildebrandt A,Wilhelm O,Sommer W

    更新日期:2016-10-01 00:00:00

  • Mean diffusivity associated with trait emotional intelligence.

    abstract::Previous neuroimaging studies have suggested that the neural bases of trait emotional intelligence (TEI) lie in the social cognition network (SCN) and the somatic marker circuitry (SMC). The current study was the first to investigate the associations of total TEI factors and subfactors with mean diffusivity (MD) of th...

    journal_title:Social cognitive and affective neuroscience

    pub_type: 杂志文章

    doi:10.1093/scan/nsz059

    authors: Takeuchi H,Taki Y,Nouchi R,Yokoyama R,Kotozaki Y,Nakagawa S,Sekiguchi A,Iizuka K,Yamamoto Y,Hanawa S,Araki T,Miyauchi CM,Sakaki K,Sassa Y,Nozawa T,Ikeda S,Yokota S,Daniele M,Kawashima R

    更新日期:2019-08-31 00:00:00