Abstract：
:Cardiogenic oscillations are small waves produced by heartbeats, which are superimposed on the pressure and flow signals at the airway opening. The aim of this study was to investigate the role of the two main factors believed to generate these oscillations: (1) contact between heart and lungs and (2) pulmonary blood flow. We studied 15 heart surgery patients on cardiopulmonary bypass so both factors could be manipulated independently. At minimal heart-lung contact pressure and flow oscillations were larger than during maximal contact (1.20+/-0.17 cmH(2)O and 2.36+/-0.08 L min(-1) vs 0.92+/-0.15 cmH(2)O and 1.78+/-0.26 L min(-1), mean+/-SD, p<0.05). Cardiogenic oscillations for pressure and flow were smaller at 50% compared to 100% pulmonary blood flow (0.80+/-0.12 cmH(2)O and 1.56+/-0.34 L min(-1) vs 1.19+/-0.14 cmH(2)O and 2.38+/-0.19 L min(-1)). We conclude that the amount of pulmonary blood flow and not the contact between heart and lungs is the main factor determining the amplitude of cardiogenic oscillations.
journal_name
Respir Physiol Neurobioljournal_title
Respiratory physiology & neurobiologyauthors
Tusman G,Suarez-Sipmann F,Peces-Barba G,Climente C,Areta M,Arenas PG,Bohm SHdoi
10.1016/j.resp.2009.04.026subject
Has Abstractpub_date
2009-07-31 00:00:00pages
247-54issue
3eissn
1569-9048issn
1878-1519pii
S1569-9048(09)00136-0journal_volume
167pub_type
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