Abstract:
OBJECTIVE:To evaluate the efficacy of the ketogenic diet in Indian children with uncontrolled epilepsy. STUDY DESIGN:Prospective observational study. SETTING:Hospital based. PATIENTS:105 children (age 4 months to 18 years) with uncontrolled epilepsy enrolled in the ketogenic diet program over a period of 9 years and followed up for 25.7+/- 20.3 months (median:17 months) on the ketogenic diet. MAIN OUTCOME MEASURES:Reduction in seizure frequency and comparison of improvement in two main groups of epilepsies, namely epileptic encephalopathies and localization related epilepsies. RESULTS:Thirty seven (35%) out of 105 children dropped out of the study and 68 remained on the diet. Thirty nine (37%) achieved 100% control, 23 (22%) achieved between 90 and 99% control, 7 (6.8%) achieved between 75 and 90% control, and 16 (15.2%) achieved between 50 and 75% control. Twenty (19%) achieved less than 50% control. Epileptic encephalopathies had a better response than localization related epilepsies. CONCLUSION:The Indian version of ketogenic diet used is well tolerated and efficacious in controlling difficult-to-control epilepsy in children. Epileptic encephalopathies respond better than localization related epilepsies.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Nathan JK,Purandare AS,Parekh ZB,Manohar HVsubject
Has Abstractpub_date
2009-08-01 00:00:00pages
669-73issue
8eissn
0019-6061issn
0974-7559pii
S097475590600494-1journal_volume
46pub_type
杂志文章abstract::Delayed diagnosis of undescended testes is a major problem. A retrospective review of 298 testes units was performed to assess the age at referral, age at operation, complications and final outcome. The mean age at referral was 57 months. Only 24% of cases were operated below 2 years. A similar pattern of delayed orch...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2008-06-01 00:00:00
abstract::A 3.5-month-old infant with undiagnosed underlying combined immunodeficiency presented with S. ceravisiae fungemia following treatment with S. boulardii containing probiotic preparation. This case highlights that the use of probiotics in sick patients may be fraught with danger. ...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2019-11-15 00:00:00
abstract::In Kumbakonam, Tamil Nadu State in India, 384 final-year female students attending the Government College for Women completed a questionnaire so the researcher could assess their knowledge of prenatal and childhood immunizations, breast feeding, weaning, oral rehydration solution (ORS), and feeding during diarrhea. 5...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To describe the clinical characteristics and outcome of Indian children infected with 2009 H1N1 influenza virus. STUDY DESIGN:Retrospective chart review. SETTING:Outpatient department and hospitalized patients in a tertiary care hospital. METHODS:Clinical details of 85 children (positive for the 2009 H1N1 ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0085-y
更新日期:2011-05-01 00:00:00
abstract:OBJECTIVE:To describe the clinical spectrum and factors associated with poor short-term outcomes in children with interstitial lung disease (ILD). DESIGN:Retrospective chart review SETTING:Pediatric Chest Clinic of a tertiary care hospital METHODOLOGY:We retrieved information regarding clinical course and laborato...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0034-z
更新日期:2013-01-08 00:00:00
abstract::We report a 12-year-old child with pseudohypoparathyroidism (PHP) whose mother had pseudopseudohypoparathyroidism. The child had low serum calcium, high phosphorous and high parathormone (PTH) levels. PHP occurs due to a defect in the guanine nucleotide binding protein (G protein). She also had hypothyroidism which is...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0225-z
更新日期:2012-12-01 00:00:00
abstract::Shwachman-Diamond Syndrome (SDS) is a rare inherited disorder characterized by pancreatic insufficiency, bone marrow dysfunction and skeletal abnormalities. It is the most common cause of pancreatic insufficiency in children after cystic fibrosis. We report a child with classical SDS who presented to us predominantly ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0138-x
更新日期:2012-09-01 00:00:00
abstract::This prospective study was conducted in a teaching hospital to identify and analyze medical errors in pediatric practice. All admitted children underwent surveillance for medical errors. Of 457 errors identified in 1286 children, medication errors were 313 (68.5%), those related to treatment procedures were 62 (13.6%)...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2008-07-01 00:00:00
abstract::Seven hundred and fifty nine children in different sectors were covered in this study, which was undertaken by observational techniques, questionnaires and physical examination. All children belonged to the age group of 6-14 years. Nearly 30% children had migrated from neighbouring districts and states. Almost 88% wer...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract::In 2017, a 10-year-old girl, who was allegedly raped and impregnated, was denied an abortion on the basis of the Medical Termination of Pregnancy Act 1971. This perspective re-examines this issue while prioritizing the best interest of the child. We recommend that boards should be constituted at district-level hospita...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-10-15 00:00:00
abstract::We report on 16 children with ingestion of magnetic foreign bodies, who were identified by a medical record review of our hospital data for the time period between January, 2017 and May, 2018. Digestive tract wall was sandwiched in 13 (75%) children and 11 (74%) had gaptic intestinal perforation. ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-06-24 00:00:00
abstract:OBJECTIVE:To determine the extent, epidemiological and clinical features of an epidemic of non-inflammatory encephalopathy in northern region of India. DESIGN:Surveillance of referred cases having unconsciousness after a short bout of fever during October and November 1997. Case control study in 7 most affected villag...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1999-11-01 00:00:00
abstract:BACKGROUND:Multiple pituitary hormone deficiency and Turner syndrome have overlapping features in peripubertal girls and is a diagnostic challenge. CASE CHARACTERISTICS:16-year-old girl having Turner phenotype undergoing evaluation for severe short stature and pubertal arrest. OBSERVATION:45,X karyotype, and multiple...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0721-z
更新日期:2015-09-01 00:00:00
abstract::In the present study, brainstorm auditory evoked responses (BAER) were recorded in 68 at risk neonates discharged from the neonatal ICU of Safdarjung Hospital. The high risk group of 35 neonates included 13 neonates with multiple (3-4) risk factors and 22 neonates with single risk factors, viz., prematurity (less than...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:Posterior reversible encephalopathy syndrome (PRES) is a benign disorder of reversible subcortical vasogenic cerebral edema. CASE CHARACTERISTICS:A 13-yr-old girl presented 4 days after complete recovery from diabetic ketoacidosis with symptoms of headache, altered sensorium, seizures, and visual loss. Ther...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2019-03-15 00:00:00
abstract::Meropenem is a new carbapenem antibacterial agent with wide spectrum of activity against gram-negative, gram-positive and anaerobic organisms. It is stable against most beta-lactamases produced by gram-negative bacteria and has greatest utility in treating severe infections in hospitalized children. It has good CSF pe...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2005-05-01 00:00:00
abstract:CONTEXT:Measles remains a major cause of child mortality in India. Measles case fatality ratios (CFRs) vary substantially between countries and even within the same community over time. We present a review of Indian community-based measles CFR studies conducted from 1975 to 2008. EVIDENCE ACQUISITION:PubMed, Cochrane ...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2009-11-01 00:00:00
abstract::An age-independent anthropometric index to identify undernourished children in the age group of 5-10 years is described. Employing a mathematical approach (linear regression analysis) on data from 238 children, the index was derived to be wt/(ht)2. Employing this index, a classification rule for identifying the undern...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract::Psychosocial assessment was carried out in 35 children with acute lymphatic leukemic, an equal number with non-leukemic chronic illness and their parents. Psychological dysfunction existed more frequently in parents of leukemic children. Depression as an initial reaction on being conveyed the diagnosis, was seen in 85...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-08-01 00:00:00
abstract:OBJECTIVE:To compare the effect of withholding maintenance phenobarbitone on breakthrough seizures. DESIGN:A double blind randomized controlled trial. SETTING:Level II neonatal intensive care unit (NICU) of a teaching hospital in Northern India. PARTICIPANTS:152 term and near term neonates (34 weeks of gestation age...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2016-12-15 00:00:00
abstract::A retrospective analysis was carried out to identify factors associated with delay in diagnosis of Kawasaki disease in a tertiary care pediatric hospital setting in Chennai, India. Over a period of 2 years, a total of 37 cases were studied. The cases were divided into Early Diagnosis Group (EDG) and Delayed Diagnosis ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0130-5
更新日期:2012-08-01 00:00:00
abstract::We conducted this study to ascertain whether health workers can routinely administer verbal autopsy (VA) to determine the cause of death in their area. The health workers were trained to administer verbal autopsy tool on the deaths occurring in the population under them. All the verbal autopsies of under-five deaths b...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of a community oral health awareness program given to mothers through trained community level workers (Junior Public Health Nurses (JPHNs) and Anganwadi workers (AWWs). METHODS:Oral health education materials were prepared based on the findings of a knowledge survey among commun...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::Thrombocytosis is a frequent finding in hemograms obtained from hospitalized and ambulatory children due to the widespread use of automated blood cell counters. Pediatricians are commonly puzzled in cases of thrombocytosis to determine the underlying cause and the need for therapy. The purpose of this review is to ass...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2008-08-01 00:00:00
abstract::Hypocalcemia is a curable cause of myocardial dysfunction and clinical congestive cardiac failure, with only stray reports available in literature. We describe 15 infants presenting with severe left ventricular dysfunction, who were found to have hypocalcemia with or without hypomagnesemia. Vitamin D deficiency was id...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0117-z
更新日期:2010-09-01 00:00:00
abstract:OBJECTIVE:Analyze the profile and outcome of children with rhabdomyosarcoma from a pediatric-oncology unit. DESIGN:Retrospective analysis of case records over 23 years (1990-2012). Setting:Government-run, tertiary-care, university hospital in Northern India. PARTICIPANTS:159 children (<12-years) with a diagnosis of ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1164-5
更新日期:2017-09-15 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of rotavirus diarrhea among hospitalized children less than 5 years of age in Kerala State and to determine the circulating strains of rotavirus in Kerala. DESIGN:Multicenter, cross-sectional study. SETTING:Eight representative hospitals in Kunnathunadu Thaluk, Ernakulam district,...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-014-0329-8
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To evaluate recovery and survival of severely wasted children without community management of acute malnutrition programme. DESIGN:Single time point follow-up (24th December 2013 - 2nd April, 2014) of severely wasted children identified in a community-based cross-sectional survey (September 2012 - October 20...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-017-1142-y
更新日期:2017-10-15 00:00:00
abstract::There is a growing body of evidence over the last years suggesting continuous positive airway pressure (CPAP) ventilation being the first choice of ventilatory support in newborns with extremely low gestational age, and early rescue surfactant treatment being as effective as prophylactic therapy. The Intubation Surfac...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0612-3
更新日期:2015-03-08 00:00:00
abstract::Iodine deficiency disorders (IDD) is a public health problem in India. A ban on the sale of uniodised salt for household consumption has been introduced in Rajasthan State since 1992. The present study was conducted in the district of Bharatpur, Rajasthan with the objective to assess the prevalence of iodine disorders...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-02-01 00:00:00