Synthesized different derivatives of low molecular fucoidan extracted from Laminaria japonica and their potential antioxidant activity in vitro.

Abstract:

:Six low molecular fucoidan (DFPS) derivatives were synthesized successfully, and their potential antioxidant activities were investigated employing various established in vitro systems. All DFPS derivatives possessed considerable antioxidant activity, and had stronger antioxidant ability than DFPS in certain tests. The benzoylated DFPS (PHDF) showed strongest scavenging activity on superoxide, hydroxyl and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, however, DFPS exhibited greatest reducing power. Available data suggested that substituted groups of DFPS played an important role on antioxidant activity, and the mechanism on influence the antioxidant activity of samples of substituted group was indicated.

journal_name

Int J Biol Macromol

authors

Wang J,Wang F,Zhang Q,Zhang Z,Shi X,Li P

doi

10.1016/j.ijbiomac.2009.02.001

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

379-84

issue

5

eissn

0141-8130

issn

1879-0003

pii

S0141-8130(09)00023-3

journal_volume

44

pub_type

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