Abstract:
:The limb remote ischaemia postconditioning (RIPOC), a newly conceived idea of applying brief limb ischaemic stimulus after onset of the myocardial ischaemia but prior to the reperfusion, can offer the possibility of applying this cardioprotective strategy to the patients with acute myocardial infraction. Although increasing numbers of circles and duration of limb ischaemia may augment the protective effect of the limb RIPOC, these ways are not feasible in a clinical setting. Morphine, a classic opioid drug, has been proven to enhance the cardioprotection obtained by the other interventions. Because both the RPIOC and opioid drugs produce the cardioprotection by multiple pathways, and there may be overlaps and cross talk in their mechanisms, we hypothesize that a combination of morphine and the limb RIPOC may produce an enhanced cardioprotection.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Xu YC,Xue FS,Liao X,Xiong J,Yang QY,Wang WL,Zhang YMdoi
10.1016/j.mehy.2009.04.004subject
Has Abstractpub_date
2009-09-01 00:00:00pages
302-5issue
3eissn
0306-9877issn
1532-2777pii
S0306-9877(09)00261-8journal_volume
73pub_type
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journal_title:Medical hypotheses
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journal_title:Medical hypotheses
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journal_title:Medical hypotheses
pub_type: 杂志文章
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journal_title:Medical hypotheses
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journal_title:Medical hypotheses
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pub_type: 杂志文章
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journal_title:Medical hypotheses
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/j.mehy.2006.12.041
更新日期:2007-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.mehy.2008.03.023
更新日期:2008-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.mehy.2010.01.001
更新日期:2010-06-01 00:00:00
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更新日期:1991-10-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2017.02.013
更新日期:2017-04-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(89)90106-0
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pub_type: 杂志文章
doi:10.1016/j.mehy.2012.10.007
更新日期:2013-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.mehy.2008.07.044
更新日期:2009-02-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.mehy.2006.08.041
更新日期:2007-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2014.03.033
更新日期:2014-07-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:1999-03-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2005.06.022
更新日期:2005-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2011-09-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2012.07.024
更新日期:2012-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/0306-9877(92)90115-s
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pub_type: 杂志文章
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更新日期:1997-10-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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