Abstract:
:To investigate the uptake and transport patterns of variously sized particles in Peyer's patches (PPs) of calves, intestinal loops were created in four newborn and two 2-month-old calves, and the loops were inoculated with various particles, including carbon black, fluorescein isothiocyanate (FITC)-labeled latex, FITC-labeled dextran, bovine serum, and recombinant mouse prion protein (rMPrP). The intestinal loops were recovered at 3, 6, 9, and 24 h in newborn calves and at 24 h in 2-month-old calves after inoculation, and the transport of the particles was examined by histological and immunohistochemical means. The uptake of the particles was quantified by estimation of signal intensities. A greater intensity was found in newborn calves compared with the 2-month-old calves. The peak uptake of carbon black, FITC-labeled latex, and rMPrP in the PPs of the distal ileum occurred at 6 h after inoculation in newborn calves and then progressively decreased with time. Uptake was also dependent on the site within the small intestine and the size of the particle studied. The transport of carbon black, FITC-labeled latex, and FITC-labeled dextran occurred via the bloodstream, the mesenteric lymph nodes, and the liver of newborn calves. rMPrP was found primarily in the interfollicular regions of the submucosa of the distal ileum of newborn calves. Thus, distal ileal PPs are probably more effective at particle absorption than the jejunal PPs, and the peak uptake of the PPs within the newborn calf occurs at 6 h after inoculation.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Sein Lwin,Inoshima Y,Ueno H,Ishiguro Ndoi
10.1007/s00441-009-0793-ysubject
Has Abstractpub_date
2009-07-01 00:00:00pages
125-35issue
1eissn
0302-766Xissn
1432-0878journal_volume
337pub_type
杂志文章abstract::The antennal lobe is the primary processing center for olfactory information in insects. To understand further the neural circuitry of this brain area, we have investigated the distribution of gamma-aminobutyric acid (GABA) and its colocalization with neuropeptides in the antennal lobe of the noctuid moth Heliothis vi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0744-z
更新日期:2009-03-01 00:00:00
abstract::Two populations of thymic lymphocytes from eight-week-old mice were separated based on the light scatter intensity they generated while passing through a flow cell analyser. The two populations were subsequently studied morphologically and analysed for the relative amount of DNA present in each cell. Cells having a lo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234855
更新日期:1979-09-01 00:00:00
abstract::The rejection of skin allografts by the larval lamprey, Lampetra reissneri, was studied by light- and electron-microscopy, with particular attention to the cell types involved in the reaction. In all allografts, melanophores were destroyed within 20-60 days (the mean survival time, 36 +/- 12 days). Neither the epiderm...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222182
更新日期:1983-01-01 00:00:00
abstract::Changes in the organisation and composition of extracellular matrix in human endometrium during the menstrual cycle and early pregnancy have been assessed by immunofluorescence. Amongst interstitial components, type-III and type V-collagens and fibronectin are present in endometrial stroma throughout the menstrual cyc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221758
更新日期:1988-07-01 00:00:00
abstract::In an attempt to determine the neural control of pancreatic D cells, the pancreatic islets of the domestic fowl were examined electron microscopically from 1 to 28 days after abdominal vagotomy. Exocytotic release of many secretory granules from D cells occurred one day after vagotomy. Rough endoplasmic reticulum deve...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233732
更新日期:1980-01-01 00:00:00
abstract::Phenotype transition of vascular smooth muscle cells (VSMCs) is implicated in vascular diseases. Angiotensin-converting enzyme 2 (ACE2) is a perspective cardiovascular target due to its ability of converting angiotensin (Ang II) to Ang (1-7). Our group recently showed that ACE2 can regulate the function of endothelial...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03259-w
更新日期:2020-12-01 00:00:00
abstract::Kidneys of 2 to 10 day-old rats of Wistar and Sprague-Dawley strains were fixed with glutaraldehyde by retrograde vascular perfusion and then prepared for observation in TEM and SEM. In addition methacrylate casts of differentiating glomerular capillaries were examined by SEM. Although the glomerular vascular pattern ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233959
更新日期:1980-01-01 00:00:00
abstract::The muscle cells of the ventricle, the branchial heart and the branchial heart appendages of Rossia macrosoma (Delle Chiaje) are studied. The ventricle myocardium has three muscle layers, while the other two organs exhibited a loose arrangement of muscle cells. The muscle cells of the ventricle, the branchial heart an...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:
更新日期:1977-12-13 00:00:00
abstract::Based on its proven anabolic effects on bone in osteoporosis patients, recombinant parathyroid hormone (PTH(1-34)) has been evaluated as a potential therapy for skeletal repair. In animals, the effect of PTH(1-34) has been investigated in various skeletal repair models such as fractures, allografting, spinal arthrodes...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-011-1188-4
更新日期:2012-03-01 00:00:00
abstract::Bullous pemphigoid antigen-1 (BPA1) and alpha(6)beta(4)-integrin colocalize at the hemidesmosomes in basal-layer keratinocytes of normal squamous epithelia. The expression of these genes was analyzed during the process of tumor cell invasion and metastasis on frozen sections of head and neck biopsies, and the structur...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100462
更新日期:2001-12-01 00:00:00
abstract::The surface ultrastructure of Kupffer cells in the rat liver has been studied by scanning electron microscopy (SEM). The results demonstrate that Kupffer cells are both significantly different and clearly distinct from endothelial cells. Kupffer cells have neither pores (and/or "sieve plates") nor fenestrations, all o...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223015
更新日期:1975-12-10 00:00:00
abstract::Human endothelial progenitor cells (EPCs) were isolated from cord blood samples and enriched by magnetic activated cell sorting method based on the CD133 marker. Cells were incubated with different doses of bacterial lipopolysaccharide, ranging from 2, 5, 10, 50, 100, 200, 250, 500, to 1000 µg/ml, for 48 h. The cell s...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03405-4
更新日期:2021-01-18 00:00:00
abstract::In the compound eye of the locust, Locusta, the cross-sectional area of the rhabdoms increases at "dusk" by 4.7-fold due to the rapid assembly of new microvillar membrane, and decreases at "dawn" by a corresponding amount as a result of pinocytotic shedding from the microvilli. The rhabdoms at night have more and long...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214807
更新日期:1982-01-01 00:00:00
abstract::In Rana temporaria tadpoles, fluorescent fibres appear in the prospective eminentia mediana, the pars intermedia and the pars distalis at Gosner's stage 25. During prometamorphosis the amount of fluorescent material increases around the developing primary capillary plexus in the eminentia mediana. In the pars intermed...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220236
更新日期:1976-09-01 00:00:00
abstract::Methods for isolation and culture of microvascular endothelial cells of the inner ear were devised to provide an in-vitro system for studying endothelial functions in this tissue. Capillaries from the stria vascularis and spiral ligament were treated enzymatically to free them from surrounding tissue. Contamination by...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214566
更新日期:1985-01-01 00:00:00
abstract::Regions within frog semitendinosus muscle that are rich in tonic muscle cells were identified histochemically by myosin adenosine triphosphatase- and succinic dehydrogenase-staining procedures. Bundles of cells still attached to tendinous insertions were removed from those sites, prepared for electron microscopy and s...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213937
更新日期:1986-01-01 00:00:00
abstract::The complex physiology of the gastrointestinal (GI) tract must permanently be adjusted according to the composition of ingested food, which requires continuous monitoring by appropriate sensory systems. Sensing the dietary constituents is thought to be mediated by chemosensory cells residing in the mucosa of the GI tr...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1137-2
更新日期:2011-05-01 00:00:00
abstract::During amphibian intestinal remodeling, thyroid hormone (TH) induces some larval epithelial cells to dedifferentiate into adult stem cells, which newly generate the absorptive epithelium analogous to the mammalian epithelium. To clarify molecular mechanisms underlying adult epithelial development, we here focus on TH ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2396-8
更新日期:2016-08-01 00:00:00
abstract::By use of the indirect immunofluorescence technique a small group of large somatostatin-positive neurons is described in the subependymal area of the anterior paraventricular thalamus of the male rat. Retrograde-tracing experiments suggest that they project to areas outside the blood-brain barrier. ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215212
更新日期:1986-01-01 00:00:00
abstract::New genome-editing approaches, such as the CRISPR/Cas system, have opened up great opportunities to insert or delete genes at targeted loci and have revolutionized genetics in model organisms like the zebrafish. The Cre-loxp recombination system is widely used to activate or inactivate genes with high spatial and temp...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2798-x
更新日期:2018-04-01 00:00:00
abstract::Dorsal root ganglia of chick embryos were cultured for one to four weeks on Maximow-slides. Puromycin was added to cultures for a pulse of 30' in a dose of 100 mug/ml medium. Particular interest was given to the ultrastructural features of the glia-neuron relations. Puromycin caused a shrinkage of the glial processes ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00225762
更新日期:1975-07-23 00:00:00
abstract::The effects of dexamethasone on the ability of cells enzymatically isolated from 21-day fetal rat calvaria to produce cartilage in vitro has been investigated. Primary cultures of single-cell suspensions of rat calvaria were grown for up to 28 days in vitro in alpha-minimal essential medium containing 15% fetal bovine...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00224728
更新日期:1989-04-01 00:00:00
abstract::The dissociation and maintenance in culture of cells derived from the mushroom bodies of adult crickets (Acheta domesticus) are described. This primary culture was developed in order to investigate maturation and differentiation of mushroom-body cells including Kenyon cells, the major intrinsic interneurons of mushroo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051023
更新日期:1998-03-01 00:00:00
abstract::Prostatic carcinoma affects 1 in 11 men and targets bone with sclerotic metastases. The study of prostate carcinoma growth in bone has been hampered by the lack of suitable animal models. We have developed an in vivo model of prostate carcinoma growth in bone by inoculating three human prostate carcinoma cell lines (P...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-001-0503-x
更新日期:2002-03-01 00:00:00
abstract::Previous studies have revealed a remarkable capacity of intracerebral grafts of embryonic brain tissue to establish extensive axonal connections with denervated areas in the brains of adult rats. In the present study we have explored the possibilities of using grafts in the spinal cord to substitute for the loss of no...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216024
更新日期:1983-01-01 00:00:00
abstract::Ten hamsters received repeated injections of 3H-thymidine for 4 days and were allowed to survive for 7, 28, 42 and 100 days. Changes in spatial distribution of the labelled cells and in labelling indices of each cell line in the gastric glands were studied at various days after 3H-thymidine, the labelled parietal cell...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226025
更新日期:1976-09-14 00:00:00
abstract::Previous light-microscopic and ultra-immunohistochemical tracer studies revealed the existence of an independent local immune response of the simian oral mucosa. This local response is attributed to the presence of minor salivary gland (MSG) duct-related lymphoid tissue. Semithin sections from a total of 263 Epon-embe...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217578
更新日期:1985-01-01 00:00:00
abstract::The distribution of radioactivity in the rat hypothalamus after intraventricular injection of tritiated luteinizing hormone-releasing hormone (LH-RH) was studied by autoradiography and compared with that expected from Fick's second law which defines the character of ordinary diffusion. The results suggest that LH-RH p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215317
更新日期:1976-05-13 00:00:00
abstract::The thyroid cells of the cream hamster, characterized by abundance of microtubules and stratification of the organelles, undergo a particular evolution when the animals grow older. These changes are characterized by an increase of the number of lysosomes which in extreme cases become so prominent that they occupy the ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215124
更新日期:1976-02-06 00:00:00
abstract::The stem cells with their distinct ability of self-renewal and differentiation are considered an innovation in wound healing. However, there is lack of studies comparing the differential effect of the type and administration route of stem cells in the wound healing context. Thus, the current study has been designed to...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2879-x
更新日期:2018-11-01 00:00:00