A general quantitative theory of forest structure and dynamics.

abstract：:Bacteriophage lambda integrates into the chromosome of its Escherichia coli host by means of a site-specific recombination between a locus on the phage chromosome (phage att site) and a locus on the bacterial chromosome (bacterial att site). The nucleotide sequence of four lambda att sites altered in site-specific rec...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hoess RH,Landy A

更新日期：1978-11-01 00:00:00

abstract：:Antischizophrenic neuroleptic drugs of the diphenylbutylpiperidine class, which includes pimozide, fluspirilene, penfluridol, and clopimozide, inhibit [3H]nitrendipine binding with IC50 values of 13-30 nM. This inhibition involves receptors for the verapamil/prenylamine class of calcium channel antagonists. These diph...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Gould RJ,Murphy KM,Reynolds IJ,Snyder SH

更新日期：1983-08-01 00:00:00

abstract：:Genomic mapping has been used to identify a region of the host genome that determines resistance to fusiform rust disease in loblolly pine where no discrete, simply inherited resistance factors had been previously found by conventional genetic analysis over four decades. A resistance locus, behaving as a single domina...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Wilcox PL,Amerson HV,Kuhlman EG,Liu BH,O'Malley DM,Sederoff RR

更新日期：1996-04-30 00:00:00

abstract：:Land plants have distinct developmental programs in haploid (gametophyte) and diploid (sporophyte) generations. Although usually the two programs strictly alternate at fertilization and meiosis, one program can be induced during the other program. In a process called apogamy, cells of the gametophyte other than the eg...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Okano Y,Aono N,Hiwatashi Y,Murata T,Nishiyama T,Ishikawa T,Kubo M,Hasebe M

更新日期：2009-09-22 00:00:00

abstract：:Mobile ectothermic animals can control their body temperatures by selecting specific thermal conditions in the environment, but embryos--trapped within an immobile egg and lacking locomotor structures--have been assumed to lack that ability. Falsifying that assumption, our experimental studies show that even early sta...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Du WG,Zhao B,Chen Y,Shine R

更新日期：2011-06-07 00:00:00

abstract：:Host-encoded factors play an important role in virus multiplication, acting in concert with virus-encoded factors. However, information regarding the host factors involved in this process is limited. Here we report the map-based cloning of an Arabidopsis thaliana gene, TOM1, which is necessary for the efficient multip...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yamanaka T,Ohta T,Takahashi M,Meshi T,Schmidt R,Dean C,Naito S,Ishikawa M

更新日期：2000-08-29 00:00:00

abstract：:In 1000 primary gastric carcinomas, 70 (7.0%) contained Epstein-Barr virus (EBV) genomic sequences detected by PCR and Southern blots. The positive tumors comprised 8 of 9 (89%) undifferentiated lymphoepithelioma-like carcinomas, 27 of 476 (5.7%) poorly differentiated adenocarcinomas, and 35 of 515 (6.8%) moderately t...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Imai S,Koizumi S,Sugiura M,Tokunaga M,Uemura Y,Yamamoto N,Tanaka S,Sato E,Osato T

更新日期：1994-09-13 00:00:00

abstract：:We have collected a set of 347 proteins that are found in eukaryotic cells but have no significant homology to proteins in Archaea and Bacteria. We call these proteins eukaryotic signature proteins (ESPs). The dominant hypothesis for the formation of the eukaryotic cell is that it is a fusion of an archaeon with a bac...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Hartman H,Fedorov A

更新日期：2002-02-05 00:00:00

abstract：:We have used restriction endonuclease mapping of cell DNA to investigate the structure of the beta-globin gene in beta-thalassemias. Among 17 individuals with beta +- and beta 0-thalassemia, we observed three patients of Indian origin with beta 0-thalassemia whose DNA revealed a consistent mapping abnormality. In one ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Orkin SH,Old JM,Weatherall DJ,Nathan DG

更新日期：1979-05-01 00:00:00

abstract：:We have isolated a cDNA clone, called Dmyd for Drosophila myogenic-determination gene, that encodes a protein with structural and functional characteristics similar to the members of the vertebrate MyoD family. Dmyd clone encodes a polypeptide of 332 amino acids with 82% identity to MyoD in the 41 amino acids of the p...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Paterson BM,Walldorf U,Eldridge J,Dübendorfer A,Frasch M,Gehring WJ

更新日期：1991-05-01 00:00:00

abstract：:We have determined the nucleotide sequences of cDNAs encoding the precursor of the beta subunit of rat lutropin, a polypeptide hormone that regulates gonadal function, including the development of gametes and the production of steroid sex hormones. The cDNAs were prepared from poly(A)+ RNA derived from the pituitary g...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chin WW,Godine JE,Klein DR,Chang AS,Tan LK,Habener JF

更新日期：1983-08-01 00:00:00

abstract：:Murine-virus-infected erythroleukemia cells cultured in a medium with dimethylsulfoxide or N,N-dimethylformamide are induced to differentiate to erythroid cells. A number of highly polar compounds have a similar effect in inducing erythroid differentiation of the virus-infected cells, as assayed by the appearance of h...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Tanaka M,Levy J,Terada M,Breslow R,Rifkind RA,Marks PA

更新日期：1975-03-01 00:00:00

abstract：:Animals are typically colonized by diverse bacterial symbionts, many of which are commensal and, in numerous cases, even essential for their host's proper development and growth. In exchange, the host must supply a sufficient array and quantity of nutrients to support the proliferation and persistence of its microbial...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Graf J,Ruby EG

更新日期：1998-02-17 00:00:00

abstract：:How can collective action evolve when individuals benefit from cooperation regardless of whether they pay its participation costs? According to one influential perspective, collective action problems are common, especially when groups are large, but may be solved when individuals who have more to gain from the collect...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Langergraber KE,Watts DP,Vigilant L,Mitani JC

更新日期：2017-07-11 00:00:00

abstract：:Mesothelin is a differentiation antigen present on the surface of ovarian cancers, mesotheliomas, and several other types of human cancers. Because among normal tissues, mesothelin is present only on mesothelial cells, it represents a good target for antibody-mediated delivery of cytotoxic agents. In the present study...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Chowdhury PS,Viner JL,Beers R,Pastan I

更新日期：1998-01-20 00:00:00

abstract：:Molecular oxygen (O(2)) began to accumulate in the atmosphere and surface ocean ca. 2,400 million years ago (Ma), but the persistent oxygenation of water masses throughout the oceans developed much later, perhaps beginning as recently as 580-550 Ma. For much of the intervening interval, moderately oxic surface waters ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Johnston DT,Wolfe-Simon F,Pearson A,Knoll AH

更新日期：2009-10-06 00:00:00

abstract：:Human liver alkaline phosphatase [ortho-phosphoric monoester phosphohydrolase (alkaline optimum), EC 3.1.3.1] was purified, and some of its physical and chemical properties were examined and compared to those of human placental alkaline phosphatase. The results indicated a different peptide structure for each, based u...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Badger KS,Sussman HH

更新日期：1976-07-01 00:00:00

abstract：:Strength and other mechanical properties of cement and concrete rely upon the formation of calcium-silicate-hydrates (C-S-H) during cement hydration. Controlling structure and properties of the C-S-H phase is a challenge, due to the complexity of this hydration product and of the mechanisms that drive its precipitatio...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Ioannidou K,Krakowiak KJ,Bauchy M,Hoover CG,Masoero E,Yip S,Ulm FJ,Levitz P,Pellenq RJ,Del Gado E

更新日期：2016-02-23 00:00:00

abstract：:Oxidation of genomic DNA forms the guanine lesion 7,8-dihydro-8-oxoguanine (8-oxoG). When in the template base position during DNA synthesis the 8-oxoG lesion has dual coding potential by virtue of its anti- and syn-conformations, base pairing with cytosine and adenine, respectively. This impacts mutagenesis, because ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Batra VK,Shock DD,Beard WA,McKenna CE,Wilson SH

更新日期：2012-01-03 00:00:00

abstract：:Mutations in the potassium channel gene KCNQ4 underlie DFNA2, an autosomal dominant form of progressive hearing loss in humans. In the mouse cochlea, the transcript has been found exclusively in the outer hair cells. By using specific antibodies, we now show that KCNQ4 is situated at the basal membrane of these sensor...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Kharkovets T,Hardelin JP,Safieddine S,Schweizer M,El-Amraoui A,Petit C,Jentsch TJ

更新日期：2000-04-11 00:00:00

abstract：:Communities have an important role to play in biodiversity conservation. However, community-based conservation as a panacea, like government-based conservation as a panacea, ignores the necessity of managing commons at multiple levels, with vertical and horizontal interplay among institutions. The study of conservatio...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Berkes F

更新日期：2007-09-25 00:00:00

abstract：:Hypophosphatasia is a heritable form of rickets/osteomalacia with extremely variable clinical expression. Severe forms are inherited in an autosomal recessive fashion; the mode of transmission of mild forms is uncertain. The biochemical hallmark of hypophosphatasia is deficient activity of the tissue-nonspecific isozy...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Henthorn PS,Raducha M,Fedde KN,Lafferty MA,Whyte MP

更新日期：1992-10-15 00:00:00

abstract：:Tropical cyclones have massive economic, social, and ecological impacts, and models of their occurrence influence many planning activities from setting insurance premiums to conservation planning. Most impact models allow for geographically varying cyclone rates but assume that individual storm events occur randomly w...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Mumby PJ,Vitolo R,Stephenson DB

更新日期：2011-10-25 00:00:00

abstract：:The AAA-ATPase thyroid hormone receptor interacting protein 13 (TRIP13), jointly with the Mad2-binding protein p31(comet), promotes the inactivation of the mitotic (spindle assembly) checkpoint by disassembling the mitotic checkpoint complex (MCC). This checkpoint system ensures the accuracy of chromosome segregation ...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Miniowitz-Shemtov S,Eytan E,Kaisari S,Sitry-Shevah D,Hershko A

更新日期：2015-09-15 00:00:00

abstract：:Recent studies have shown that human cytomegalovirus (HCMV) can induce a robust increase in lipid synthesis which is critical for the success of infection. In mammalian cells the central precursor for lipid biosynthesis, cytosolic acetyl CoA (Ac-CoA), is produced by ATP-citrate lyase (ACLY) from mitochondria-derived c...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Vysochan A,Sengupta A,Weljie AM,Alwine JC,Yu Y

更新日期：2017-02-21 00:00:00

abstract：:In the troposphere, methanol (CH3OH) is present ubiquitously and second in abundance among organic gases after methane. In the surface ocean, methanol represents a supply of energy and carbon for marine microbes. Here we report direct measurements of air-sea methanol transfer along a ∼10,000-km north-south transect of...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yang M,Nightingale PD,Beale R,Liss PS,Blomquist B,Fairall C

更新日期：2013-12-10 00:00:00

abstract：:To understand the evolution of a Theory of Mind, we need to understand the selective factors that might have jumpstarted its initial evolution. We argue that a subconscious, reflexive appreciation of others' intentions, emotions, and perspectives is at the roots of even the most complex forms of Theory of Mind and tha...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Seyfarth RM,Cheney DL

更新日期：2013-06-18 00:00:00

abstract：:When treated with heat-killed bacterial cells, mosquito cells in culture respond by up-regulating several proteins. Among these is a 66-kDa protein (p66) that is secreted from cells derived from both Aedes aegypti and Aedes albopictus. p66 was degraded by proteolysis and gave a virtually identical pattern of peptide p...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Yoshiga T,Hernandez VP,Fallon AM,Law JH

更新日期：1997-11-11 00:00:00

abstract：:It has been nearly 40 y since it was suggested that genomic methylation patterns could be transmitted via maintenance methylation during S phase and might play a role in the dynamic regulation of gene expression during development [Holliday R, Pugh JE (1975) Science 187(4173):226-232; Riggs AD (1975) Cytogenet Cell Ge...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Bestor TH,Edwards JR,Boulard M

更新日期：2015-06-02 00:00:00

abstract：:We introduce the concept of hybridization chain reaction (HCR), in which stable DNA monomers assemble only upon exposure to a target DNA fragment. In the simplest version of this process, two stable species of DNA hairpins coexist in solution until the introduction of initiator strands triggers a cascade of hybridizat...

journal_title：Proceedings of the National Academy of Sciences of the United States of America

authors： Dirks RM,Pierce NA

更新日期：2004-10-26 00:00:00