Fetal pathology in second-trimester miscarriages.

Abstract:

OBJECTIVE:We aimed to analyze, based upon autopsy, the main characteristics of miscarriages in the second trimester. METHODS:We have processed the results of fetopathological investigations of 544 aborted fetuses resulting from 486 second-trimester miscarriages. RESULTS:Malformation could be identified in 13.05% of all cases. In almost one third of the patients there was a positive history. In the cases having a malformation, expressed dominance of male fetuses could be observed. Among the fetopathologically identified malformations, 49 were isolated. The most common was the single umbilical artery (22.4%). In 1.3% of the cases a chromosome aberration was verified. CONCLUSION:Miscarriage in pregnancies complicated by a malformation occurs approximately 3 weeks earlier than in cases without a confirmed malformation. There is practically no difference between affected and unaffected miscarriages as far as the cumulative ratio of positive history is concerned. A single umbilical artery alone predisposes to miscarriage, while in association with other malformations it may result from chromosome aberration.

journal_name

Fetal Diagn Ther

authors

Joó JG,Beke A,Berkes E,Papp Z,Rigó J Jr,Papp C

doi

10.1159/000210832

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

186-91

issue

2

eissn

1015-3837

issn

1421-9964

pii

000210832

journal_volume

25

pub_type

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