Abstract：
:The histogenesis and cornification of claws in zebrafinch embryos has been analyzed. At 10-12 days post-deposition, the epidermis at the tip of the toes forms placode-like anlage associated with a mesenchymal condensation and with a terminal phalange. Claws seem to be modified scales, the dorsal side of which becomes the unguis whereas a ventral scale is the origin of the sub-unguis. At 14-15 days, numerous keratinocytes form the unguis, the corneous layer of which becomes thicker than in the sub-unguis and accumulates beta-keratin and lipids. Keratin bundles are mainly directed toward the tip of the claw and have a prevalent parallel orientation. Unguis corneocytes are thicker and accumulate more beta-keratin than corneocytes of the sub-unguis. Mature corneocytes become partially fused in a compact corneous layer at 17-18 days, near hatching. During growth of the unguis, the embryonic epidermis and beta-keratin cells curve over the tip of the claw and localize in the ventral part of the claw, forming the claw pad. The latter is shed at hatching leaving the pointed claw made of harder corneous layers in the unguis side of the claw.
journal_name
Anat Sci Intjournal_title
Anatomical science internationalauthors
Alibardi Ldoi
10.1007/s12565-009-0015-4subject
Has Abstractpub_date
2009-09-01 00:00:00pages
189-99issue
3eissn
1447-6959issn
1447-073Xjournal_volume
84pub_type
杂志文章abstract：:Kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that serve as sources of force for intracellular transport and cell division. Recent studies have revealed new roles of KIFs as microtubule stabilizers and depolymerizers, and these activities are fundamental to cellular morphogenesis and m...
journal_title：Anatomical science international
pub_type： 杂志文章,评审
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pub_type： 传,历史文章,杂志文章
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