Multiple, novel biologically active endophytic actinomycetes isolated from upper Amazonian rainforests.

Abstract:

:Microbial biodiversity provides an increasingly important source of medically and industrially useful compounds. We have isolated 14 actinomycete species from a collection of approximately 300 plant stem samples from the upper Amazonian rainforest in Peru. All of the cultured isolates produce substances with inhibitory activity directed at a range of potential fungal and bacterial pathogens. For some organisms, this activity is very broad in spectrum while other organisms show specific activity against a limited number of organisms. Two of these organisms preferentially inhibit bacterial test organisms over eukaryotic organisms. rDNA sequence analysis indicates that these organisms are not equivalent to any other cultured deposits in GenBank. Our results provide evidence of the untapped biodiversity in the form of biologically active microbes present within the tissues of higher plants.

journal_name

Microb Ecol

journal_title

Microbial ecology

authors

Bascom-Slack CA,Ma C,Moore E,Babbs B,Fenn K,Greene JS,Hann BD,Keehner J,Kelley-Swift EG,Kembaiyan V,Lee SJ,Li P,Light DY,Lin EH,Schorn MA,Vekhter D,Boulanger LA,Hess WM,Vargas PN,Strobel GA,Strobel SA

doi

10.1007/s00248-009-9494-z

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

374-83

issue

2

eissn

0095-3628

issn

1432-184X

journal_volume

58

pub_type

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