Does premature luteinization or early surge of LH impair cycle outcome? Report of two successful outcomes.

Abstract:

PURPOSE:To report two successful antagonist IVF cycles; one ending up with pregnancy despite premature luteinization (case 1, aged 35 years), and the other with the retrieval of high quality oocytes despite premature ovulation (case 2, aged 39 years). METHODS:Serum LH was 36 and 47 IU/L on cycle day 7 before antagonist administration, which was then brought to 6.94 and 3.92 IU/L by antagonist administration, and kept below these levels throughout the remaining stimulation in case 1 and 2 respectively. Serum progesterone was 1.42 and 5.5 ng/mL on the day of hCG respectively. Ten metaphase II (MII) oocytes were harvested wherein 3 grade A embryos were transferred in case 1, and seven good quality MII oocytes were retrieved wherein six embryos were cryopreserved in case 2. CONCLUSIONS:More precise cut thresholds for both LH and progesterone are necessary for accurate prediction of the cycle outcomes.

journal_name

J Assist Reprod Genet

authors

Sönmezer M,Pelin Cil A,Atabekoğlu C,Ozkavukçu S,Ozmen B

doi

10.1007/s10815-009-9299-5

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

159-63

issue

2-3

eissn

1058-0468

issn

1573-7330

journal_volume

26

pub_type

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