Abstract:
AIM:To evaluate the resistance to ex vivo bacterial leakage over a 40-day period of root canal fillings with five new root canal sealers: RC Sealer, Epiphany, EndoREZ, GuttaFlow and Acroseal, compared with Apexit, AH Plus and RoekoSeal. METHODOLOGY:One hundred and forty-four single rooted human teeth were divided randomly into eight test (n = 15) and two control groups (n = 12). The root canals were filled using a single cone technique with gutta-percha except in the Epiphany and EndoREZ groups. These were filled with Resilon and resin-coated gutta-percha, respectively. The gutta-percha surface of the GuttaFlow group was coated with an experimental primer prior to filling. Positive controls were filled with gutta-percha without sealer and tested with bacteria, whereas negative controls were sealed with wax to test the seal between the chambers. Filled roots were incorporated in a split chamber model system using Streptococcus mutans as a microbial marker. Leakage was assessed for turbidity of the broth in the lower chamber every day for 40 days. Survival analysis was performed using the Kaplan-Meier product limit method and event times were compared using the Log-rank test (alpha = 0.05). RESULTS:Epiphany, GuttaFlow with test primer and Apexit prevented leakage significantly better than AH Plus, RC Sealer, RoekoSeal, EndoREZ and Acroseal (P < 0.05). None of the specimens in the AH Plus, RC Sealer, RoekoSeal and EndoREZ groups resisted bacterial penetration for 40 days. CONCLUSION:The new sealers, Epiphany and GuttaFlow with primer, along with Apexit, showed better resistance to bacterial penetration than the other new or traditional sealers tested.
journal_name
Int Endod Jjournal_title
International endodontic journalauthors
Eldeniz AU,Ørstavik Ddoi
10.1111/j.1365-2591.2008.01509.xsubject
Has Abstractpub_date
2009-04-01 00:00:00pages
303-12issue
4eissn
0143-2885issn
1365-2591pii
IEJ1509journal_volume
42pub_type
杂志文章abstract:AIM:To assay the toxicity of the single-methacrylate-based sealer urethane dimethacrylate (UDMA) (EndoRez) in terms of cell growth and pro-inflammatory cytokines release, in expanded ex vivo human dental pulp stem cells (hDPSCs), human periodontal ligament stem cells (hPDLSCs), human gingival fibroblasts (hGFs) and hum...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12230
更新日期:2014-09-01 00:00:00
abstract:AIM:The aim of this in vitro study was to evaluate the antimicrobial effectiveness of electro-chemically activated water (ECA) as an endodontic irrigation solution. METHODOLOGY:The root canals of 60 caries-free, single-rooted, adult, maxillary, anterior human teeth were instrumented and irrigated in a similar method t...
journal_title:International endodontic journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2591.2001.00258.x
更新日期:2001-04-01 00:00:00
abstract::The antibacterial activity of four elements (zinc, copper, fluoride and mercury), previously reported to be released from dental restorative materials, was investigated. This was carried out using two aerobic micro-organisms isolated from dentine beneath cavities in the ferret. These were grown in the presence of the ...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1989.tb00499.x
更新日期:1989-01-01 00:00:00
abstract:AIM:To investigate whether apical periodontitis lesions infected by Epstein-Barr virus (EBV) exhibit higher levels of oxidative stress biomarkers [8-hydroxydeoxyguanosine (8-OHdG) and oxidized glutathione (GSSG)] and bone resorption regulators [receptor activator of nuclear factor (NF-κB) ligand (RANKL) and osteoproteg...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12886
更新日期:2018-06-01 00:00:00
abstract:AIM:To determine whether chemokines such as SDF-1 and monocyte chemoattractant protein-1 (MCP-1) are responsible for hydrogen peroxide (H2 O2 )-induced extracellular matrix (ECM) degradation and to identify the underlying mechanism in human dental pulp cells (HDPCs). METHOD:Human dental pulp cells were exposed to 0.4 ...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12147
更新日期:2014-03-01 00:00:00
abstract:AIM:To evaluate the intratubular antimicrobial activity of several oxidant and chelating agents associated with or without surfactants in experimentally infected root canals, using confocal laser scanning microscopy. METHODOLOGY:Twenty-four dentine blocks from bovine incisors were contaminated for 5 days with Enteroco...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12863
更新日期:2018-04-01 00:00:00
abstract:AIM:To identify the role of astrocyte elevated gene-1 (AEG-1) and the mechanism underlying the inflammatory response in dental pulp cells. METHODOLOGY:Astrocyte elevated gene-1 expression was detected at different stages of pulpitis in a rat model using immunohistochemistry. RT-qPCR and Western blot were used to asses...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12921
更新日期:2018-10-01 00:00:00
abstract::To explain dentists' variation in endodontic retreatment decision making a praxis concept (PC) has been generated. PC assumes that practitioners operate along a health continuum. Various periapical conditions are then perceived as different stages on a continuous health scale, based on their radiographic appearance. P...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.1998.00170.x
更新日期:1998-09-01 00:00:00
abstract:AIM:To compare root canal treatments performed before and after education in a nickel-titanium rotary technique (NiTiR) with respect to costs for instrumentation and number of instrumentation sessions in a County Public Dental Service in Sweden. METHODOLOGY: Following education, 77% of the general dental practitioner...
journal_title:International endodontic journal
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1365-2591.2012.02019.x
更新日期:2012-07-01 00:00:00
abstract::Following extraction of a symptomatic mandibular premolar which had been subjected to two periradicular surgical procedures, significant apical healing was identified histologically. The implications of these findings are discussed in relation to contemporary advocated treatment regimens, case assessment, and interpre...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1994.tb00280.x
更新日期:1994-11-01 00:00:00
abstract:AIM:To investigate the prevalences of four Treponema species in primary root canal infections using a nested PCR assay. METHODOLOGY:Samples were obtained from 32 infected root canals. Twenty-two cases showed chronic asymptomatic periradicular lesions and 10 symptomatic cases were diagnosed as acute apical periodontiti...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.0143-2885.2003.00607.x
更新日期:2003-01-01 00:00:00
abstract:AIM:To evaluate the antimicrobial efficacy of Ocimum sanctum, Cinnamomum zeylanicum, Syzygium aromaticum and 3% sodium hypochlorite (NaOCl) against Enterococcus faecalis in planktonic suspension and biofilm phenotypes. METHODOLOGY:The antibacterial efficacy of different concentrations of aqueous ethanolic extracts of ...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.12058
更新日期:2013-08-01 00:00:00
abstract:AIM:To compare torque and angle of rotation at fracture of new and used K3 rotary instruments. The relation between size of instrument and torque at fracture was also investigated. METHODOLOGY:Nickel-titanium (Ni-Ti).06 K3 rotary instruments were used in a crown-down manner at 300 r.p.m. to prepare canals in resin blo...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.2003.00732.x
更新日期:2003-11-01 00:00:00
abstract:AIM:To test the chemical-physical properties and apatite-forming ability of experimental fluoride-doped calcium silicate cements designed to create novel bioactive materials for use in endodontics and oral surgery. METHODOLOGY:A thermally treated calcium silicate cement (wTC) containing CaCl(2) 5%wt was modified by ad...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2011.01907.x
更新日期:2011-10-01 00:00:00
abstract:AIM:To investigate the smallest dentine thickness in mesial canals of mandibular molars along the cervical and middle thirds of the root by means of a micro-computed tomographic (micro-CT) technology and digital image analysis. METHODOLOGY:Fifty mesial roots of mandibular molars having two independent canals (mesiobuc...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.13141
更新日期:2019-10-01 00:00:00
abstract:AIM:To investigate differences in the root canal morphology of permanent mandibular molar teeth at various ages. METHODOLOGY:Four hundred and eighty permanent mandibular first and second molars were examined. First and second molars were divided into six and five groups, respectively, according to the age of the patie...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2008.01428.x
更新日期:2008-10-01 00:00:00
abstract:AIM:To investigate the influence of biofilm structure on the biofilm removal capacity of endodontic irrigants and to study changes in the architecture of the remaining biofilms. METHODOLOGY:Streptococcus oralis J22 and Actinomyces naeslundii T14V-J1 were cocultured under different growth conditions on saliva-coated hy...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.13027
更新日期:2019-04-01 00:00:00
abstract:AIM:To assess and correlate three distinct states of severely painful endodontically derived inflammation with their depiction on periapical radiographs using periapical index (PAI) scores. METHODOLOGY:During a period of 15 months, 368 consecutively enrolled patients with suspected endodontic emergency conditions were...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/iej.13407
更新日期:2021-02-01 00:00:00
abstract::During the past few decades several authors have perpetuated the notion that nearly half of all periapical lesions are radicular cysts. A few studies, based on meticulous serial sectioning of periapical lesions retrieved in toto, have shown that the actual incidence of radicular cyst is only about 15% of all periapica...
journal_title:International endodontic journal
pub_type: 杂志文章,评审
doi:10.1046/j.1365-2591.1998.00146.x
更新日期:1998-05-01 00:00:00
abstract:AIM:To investigate the antimicrobial activity of root canal sealers on Enterococcus faecalis, either allowing or avoiding direct contact between sealers and bacteria. METHODOLOGY:Filter paper discs were immersed in standardized E. faecalis suspensions and exposed to freshly mixed sealers (MCS, AH Plus, Grossman's seal...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2005.00981.x
更新日期:2005-07-01 00:00:00
abstract:AIM:To evaluate the clinical outcome of 'Lesion Sterilization and Tissue Repair' (LSTR) therapy for endodontic treatment of primary teeth. METHODOLOGY:A mixture of metronidazole, ciprofloxacin, and minocycline (3Mix) in ointment (macrogol mixed with propylene glycol: MP) or in a root canal sealer was used to disinfect...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.0143-2885.2004.00771.x
更新日期:2004-02-01 00:00:00
abstract:AIM:The aim of this study was to determine the percentage of anatomical canal configurations of the mesiobuccal root of the maxillary first molar in Japanese patients. METHODOLOGY:Three hundred teeth were obtained from general dentists who knew absolutely that they were extracted from Japanese patients. The distobucca...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.1999.00186.x
更新日期:1999-03-01 00:00:00
abstract::The purpose of this investigation was to study the effects of a Nd:YAG laser on the cut surface of teeth using scanning electron microscopy (SEM). Eighteen single-rooted teeth were cleaned, shaped, and obturated with gutta-percha and root canal sealer. The apical 3 mm of each tooth were resected with a diamond fissure...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.1992.tb00758.x
更新日期:1992-11-01 00:00:00
abstract::CLINICAL TECHNIQUE: It is generally accepted that the success of root-canal treatment is mainly dependent on the proper cleaning, shaping and hermetic obturation of root canals. Obturation of the root canal is of importance as 60% of endodontic failures are attributable to incomplete obliteration of the root-canal sys...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.1999.00180.x
更新日期:1999-01-01 00:00:00
abstract:AIM:To engineer systems using polyisoprene (PI) or polycaprolactone (PCL) and nanometric bioactive glass 45S5 (BG) that could create a hydroxyapatite interface and thus ultimately make the use of an endodontic sealer unnecessary. METHODOLOGY:Different composites using PI or PCL as matrix material were prepared with BG...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2010.01772.x
更新日期:2010-11-01 00:00:00
abstract:AIM:This study was designed to examine whether enamel matrix derivative (EMD) could induce reparative dentine formation without eliciting adverse side-effects in pulpotomized teeth in the miniature swine. METHODOLOGY:Pulpotomy was performed in 36 mandibular incisor teeth from 11 adult miniature swine. Following the su...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.2002.00556.x
更新日期:2002-05-01 00:00:00
abstract:AIM:The apical sealing ability of three different endodontic sealers was evaluated in extracted teeth using dye penetration. METHODOLOGY:The root canals of 99 extracted human maxillary central incisors were prepared sequentially 2 mm beyond the apical foramen with a size 55 Nitiflex file. The teeth were divided into t...
journal_title:International endodontic journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1365-2591.2000.00247.x
更新日期:2000-01-01 00:00:00
abstract::The diameters of six different sized Lightspeed cutting heads were measured using a modified optical micrometer. Six specimens of instrument sizes 20, 22.5, 27.7, 30, 32.5 and 45 were examined. Except for one cutting head of size 30, all the recorded diameters were oversized compared to the expected diameter and the p...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1046/j.1365-2591.1998.00163.x
更新日期:1998-07-01 00:00:00
abstract:AIM:To identify the suitable ratio of alternative radiopacifiers to impart the necessary radiopacity to calcium silicate cements (CSC) and assess the purity of the radiopacifying agents. METHODOLOGY:Alternative radiopacifying materials for incorporation into CSC included barium sulphate, titanium oxide, zinc oxide, go...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2009.01621.x
更新日期:2010-01-01 00:00:00
abstract:AIM:To compare the toxicity of methacrylate resin-based root canal sealers with sealers based on epoxy resin and silicone by two-well established cell culture methods. METHODOLOGY:Specimens of AH Plus, EndoREZ, RoekoSeal and Epiphany were prepared for direct contact in the Millipore filter diffusion test and as extrac...
journal_title:International endodontic journal
pub_type: 杂志文章
doi:10.1111/j.1365-2591.2007.01321.x
更新日期:2008-01-01 00:00:00