Estrogen and progesterone receptors in smooth muscle component of deep infiltrating endometriosis.

Abstract:

OBJECTIVE:To analyze the expression of estrogen (ER) and progesterone (PR) receptors in the smooth muscle component (SMC) of deep infiltrating endometriosis (DIE). DESIGN:A prospective clinical and pathologic study of 60 cases of DIE. SETTING:University Hospital Department of Gynacology. PATIENT(S):Sixty patients with symptomatic DIE (uterosacral endometriosis n = 14; bladder endometriosis n = 10; colonic endometriosis n = 16; rectovaginal endometriosis n = 20). INTERVENTION(S):Laparoscopic surgery. MAIN OUTCOME MEASURE(S):The expression of ER and PR was studied by immunohistochemistry in the SMC directly around endometriotic foci and at distance (at least >1.5 cm) from them in correlation with proliferative and secretory phases of cycle. RESULTS:The ER and PR were present in the SMC of DEI in each location excepting colonic endometriosis where ER were absent. Independently of cycle's phases the PR were more abundant than ER. With the exception of rectovaginal endometriosis, where the ER and PR were more abundant in the proliferative than in the secretory phase, in other locations the ER and PR did not differ significantly with cycle's phases. Last, if ER and PR were more abundant in SMC around endometriotic foci than at a distance from them. However, the difference was not significant. CONCLUSIONS:Our data substantially confirm for the first time that in various forms of DIE, ER and PR are present not only in glands and stroma but also in the smooth muscle major histologic component of this disease.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Noël JC,Chapron C,Bucella D,Buxant F,Peny MO,Fayt I,Borghese B,Anaf V

doi

10.1016/j.fertnstert.2008.12.114

subject

Has Abstract

pub_date

2010-04-01 00:00:00

pages

1774-7

issue

6

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(08)04813-9

journal_volume

93

pub_type

杂志文章
  • Selection of patients for natural cycle in vitro fertilization combined with in vitro maturation of immature oocytes.

    abstract:OBJECTIVE:To determine a successful method of selecting patients for natural cycle IVF combined with in vitro maturation (IVM) of immature oocytes and to determine treatment efficacy. DESIGN:Retrospective analysis of IVF treatments. SETTING:Hospital IVF clinic. PATIENT(S):Women with infertility according to ovarian ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.01.066

    authors: Lim JH,Yang SH,Xu Y,Yoon SH,Chian RC

    更新日期:2009-04-01 00:00:00

  • The cation composition of the seminal plasma and prostatic fluid and its correlation to semen quality.

    abstract::The concentrations of calcium, magnesium, and zinc were measured by atomic absorption spectrometry. The concentrations of all three cations were found to be strongly correlated with one another and with acidity (pH). Analysis of the relative concentrations in prostatic fluid, split ejaculates, and whole seminal plasma...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)43281-4

    authors: Homonnai ZT,Matzkin H,Fainman N,Paz G,Kraicer PF

    更新日期:1978-05-01 00:00:00

  • A decade of experience emphasizes that testing for Y microdeletions is essential in American men with azoospermia and severe oligozoospermia.

    abstract:OBJECTIVE:To evaluate the benefit of Y microdeletion testing. DESIGN:Retrospective analysis. SETTING:University-based male fertility clinic and genetics laboratory. PATIENT(S):A total of 1,591 men with sperm concentrations less than 5 million sperm/mL. INTERVENTION(S):Semen analysis, Y microdeletion testing, microd...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2009.09.006

    authors: Stahl PJ,Masson P,Mielnik A,Marean MB,Schlegel PN,Paduch DA

    更新日期:2010-10-01 00:00:00

  • Surgically induced ovulation in the polycystic ovary syndrome: wedge resection revisited in the age of laparoscopy.

    abstract:OBJECTIVE:To provide an up-to-date comprehensive review of published data on laparoscopic methods of ovulation induction in the polycystic ovary syndrome (PCOS). Areas to be considered include the historical background of these procedures, their outcomes as reported in the literature, and their potential adverse effect...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,评审

    doi:10.1016/s0015-0282(16)57408-1

    authors: Donesky BW,Adashi EY

    更新日期:1995-03-01 00:00:00

  • Clinical outcome of using ganirelix acetate versus a 4-day follicular phase leuprolide acetate protocol in unselected women undergoing in vitro fertilization.

    abstract:OBJECTIVE:To compare the clinical outcome of controlled ovarian hyperstimulation (COH) in unselected patients undergoing IVF using multidose ganirelix acetate versus 4 days of administration of leuprolide acetate. DESIGN:Retrospective cohort study. SETTING:A fertility and IVF center. PATIENT(S):Two hundred forty-sev...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(03)00500-4

    authors: Posada MN,Vlahos NP,Jurema MW,Bracero NJ,Wallach EE,Garcia JE

    更新日期:2003-07-01 00:00:00

  • Efficacy of methotrexate treatment in extrauterine pregnancies defined by stable or increasing human chorionic gonadotropin concentrations.

    abstract:OBJECTIVE:To evaluate the efficacy of methotrexate treatment in selected cases of extrauterine pregnancy (EUP) defined by stable or increasing hCG concentration. DESIGN:Prospective cohort study. SETTING:Gynecology department of the Lis Maternity Hospital. PATIENT(S):Fifty women with EUP diagnosed whenever an intraut...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(01)03256-3

    authors: Gamzu R,Almog B,Levin Y,Avni A,Jaffa A,Lessing JB,Baram A

    更新日期:2002-04-01 00:00:00

  • Sexuality after sigmoid vaginoplasty in patients with Mayer-Rokitansky-Küster-Hauser syndrome.

    abstract:OBJECTIVE:To investigate the functional and sexual outcome of sigmoid vaginoplasty in patients with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. DESIGN:Prospective study. SETTING:University hospital. PATIENT(S):Fifty-nine consecutive patients with MRKH syndrome. INTERVENTION(S):Forty-eight patients underwent sig...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.12.015

    authors: Carrard C,Chevret-Measson M,Lunel A,Raudrant D

    更新日期:2012-03-01 00:00:00

  • Lack of effect of short-term diazoxide administration on luteinizing hormone secretion in women with polycystic ovary syndrome.

    abstract:OBJECTIVE:To test the hypothesis that an acute reduction in circulating insulin affects LH secretion in women with polycystic ovary syndrome (PCOS). DESIGN:Prospective study in normal and PCOS women. SETTING:General Clinical Research Centers at the University of Virginia, the Medical College of Virginia, and the Mass...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.11.109

    authors: Evans WS,Taylor AE,Boyd DG,Johnson ML,Matt DW,Jimenez Y,Nestler JE

    更新日期:2007-07-01 00:00:00

  • Effects of ovarian endometrioma on embryo quality.

    abstract::The proportions of good, fair, and poor embryos in 13 women with bilateral endometriomas were compared with those of 39 women without endometriomas and were found to be similar (47.2% vs. 41.1%, 28.3% vs. 32.8%, and 24.3% vs. 26.0%, respectively). Therefore, it appears that the presence of bilateral endometriomas duri...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.03.002

    authors: Reinblatt SL,Ishai L,Shehata F,Son WY,Tulandi T,Almog B

    更新日期:2011-06-30 00:00:00

  • Antisperm antibodies and fertility after vasovasostomy: a follow-up study of 216 men.

    abstract::A group of 216 vasovasostomized men were tested with the mixed antiglobulin reaction for immunoglobulin (Ig)G, IgA, and secretory IgA antisperm antibodies bound to the sperm membrane. Free antisperm antibodies in serum and seminal plasma were detected with the gelatin agglutination test and the tray agglutination test...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Meinertz H,Linnet L,Fogh-Andersen P,Hjort T

    更新日期:1990-08-01 00:00:00

  • The antiprogesterone Org 31710 inhibits human blastocyst-endometrial interactions in vitro.

    abstract:OBJECTIVE:To investigate the effect of the anti-P Org 31710 on human blastocyst attachment to cultured endometrial epithelial cells. DESIGN:Experimental in vitro study. SETTING:University hospital. PATIENT(S):Eleven fertile endometrial donors. INTERVENTION(S):Timed endometrial biopsy for cell cultures. MAIN OUTCOM...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2004.08.040

    authors: Petersen A,Bentin-Ley U,Ravn V,Qvortrup K,Sørensen S,Islin H,Sjögren A,Mosselmann S,Hamberger L

    更新日期:2005-04-01 00:00:00

  • Semen quality in men with disseminated testicular cancer: relation with human chorionic gonadotropin beta-subunit and pituitary gonadal hormones.

    abstract:OBJECTIVE:To compare the semen quality and hormonal status between patients with testicular cancer and normal versus increased serum levels of beta-hCG. DESIGN:Retrospective study. SETTING:Academic research environment. PATIENT(S):All 203 patients with testicular cancer who required chemotherapy in the period 1995-2...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.03.016

    authors: de Bruin D,de Jong IJ,Arts EG,Nuver J,Dullaart RP,Sluiter WJ,Hoekstra HJ,Sleijfer DT,Gietema JA

    更新日期:2009-06-01 00:00:00

  • Superovulation with intrauterine insemination in the treatment of infertility: a possible alternative to gamete intrafallopian transfer and in vitro fertilization.

    abstract::In vitro fertilization and embryo transfer (IVF-ET) and gamete intrafallopian transfer (GIFT) are used to treat intractable infertility in women with no distortion of the pelvic viscera, despite the lack of controlled trials demonstrating efficacy. The mechanism of any purportedly enhanced cycle fecundity in ovulatory...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)59414-x

    authors: Dodson WC,Whitesides DB,Hughes CL Jr,Easley HA 3rd,Haney AF

    更新日期:1987-09-01 00:00:00

  • Changing parameters of donor semen.

    abstract::Effective contraception and easily available abortion have contributed to the decline of adoptable children. This decline has resulted in a marked increase in the demand for AID. The provider of donor semen must establish minimal semen criteria to meet this demand effectively. During the past 8 years the authors have ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)45923-6

    authors: Leto S,Frensilli FJ

    更新日期:1981-12-01 00:00:00

  • Memory complaints associated with the use of gonadotropin-releasing hormone agonists: a preliminary study.

    abstract:OBJECTIVES:To study the effect of GnRH agonist (GnRH-a) treatment on memory and to assess the role of psychological factors. DESIGN:A randomized prospective study. SETTING:An academic teaching hospital. PARTICIPANTS:Women with endometriosis and infertility or endometriosis alone. MAIN OUTCOME MEASURES:Memory Observ...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0015-0282(16)58351-4

    authors: Newton C,Slota D,Yuzpe AA,Tummon IS

    更新日期:1996-06-01 00:00:00

  • Influence of growth factors in defined culture medium on in vitro development of mouse embryos.

    abstract::Two-cell mouse embryos were cultured in Ham's F-10 medium (Gibco, Grand Island, NY) supplemented with various concentrations of transferrin, insulin, epidermal growth factor, platelet-derived growth factor, or fibroblast growth factor. Rates of development and the cell numbers per blastocyst were compared between embr...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)54082-5

    authors: Colver RM,Howe AM,McDonough PG,Boldt J

    更新日期:1991-01-01 00:00:00

  • Endometrial preparation for frozen-thawed embryo transfer with or without pretreatment with gonadotropin-releasing hormone agonist.

    abstract:OBJECTIVE:To test the efficacy of endometrial preparation with exogenous steroids, without pretreatment with gonadotropin-releasing hormone (GnRH) agonist, in women with normal ovarian function. DESIGN:Prospective randomized study. SETTING:Private outpatient infertility clinic. PATIENT(S):Two hundred ninety-six wome...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0015-0282(02)02960-6

    authors: Dal Prato L,Borini A,Cattoli M,Bonu MA,Sciajno R,Flamigni C

    更新日期:2002-05-01 00:00:00

  • Laparoscopic management of hydrosalpinges before in vitro fertilization-embryo transfer: salpingectomy versus proximal tubal occlusion.

    abstract:OBJECTIVE:To compare ovarian response and IVF-ET cycle outcome in patients with hydrosalpinges managed by either laparoscopic salpingectomy or proximal tubal occlusion. DESIGN:Retrospective analysis. SETTING:Tertiary-care assisted reproductive technology program. PATIENT(S):One hundred four consecutive fresh IVF-ET ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(00)01742-8

    authors: Surrey ES,Schoolcraft WB

    更新日期:2001-03-01 00:00:00

  • Thrombophilic gene polymorphisms are risk factors for unexplained infertility.

    abstract::Earlier studies have shown inherited thrombophilia to be a risk factor for recurrent implantation failure, raising the question of whether this risk is related to the underlying cause of unexplained infertility or to the mechanisms involved in the implantation process. When nine thrombophilic gene polymorphisms were c...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.07.1782

    authors: Coulam CB,Jeyendran RS

    更新日期:2009-04-01 00:00:00

  • Studies of carbohydrate and lipid metabolism in women using the progesterone-T intrauterine device for six months: blood glucose, insulin, cholesterol, and triglyceride levels.

    abstract::A prospective, detailed study of both lipid and carbohydrate metabolism was carried out in 35 women who used a progesterone-T type intrauterine device (IUD). A 3-hour oral glucose tolerance test was performed in each woman before the IUD was inserted and again after 6 months of use. There was no change in the patient...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)43273-5

    authors: Spellacy WN,Buhi WC,Birk SA

    更新日期:1978-05-01 00:00:00

  • Isolated spermatogonia protrude active pseudopodia in vitro.

    abstract::When dispersed spermatogenic cells obtained by enzymatic digestion from prepuberal mice, adult male mice, nonazoospermic men and normospermic men were observed live using Normarski optics, it was found that, respectively, 47.4%, 1.4%, 5.1%, and 2.4% of them protruded active pseudopodia. These cells were 8 to 10 mum in...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.06.055

    authors: Tanaka A,Nagayoshi M,Awata S,Himeno N,Tanaka I,Kusunoki H

    更新日期:2008-08-01 00:00:00

  • Number of biopsied trophectoderm cells is likely to affect the implantation potential of blastocysts with poor trophectoderm quality.

    abstract:OBJECTIVE:To evaluate whether the developmental potential of the blastocyst is affected by the number of trophectoderm (TE) cells biopsied in preimplantation genetic diagnosis (PGD) cycles. DESIGN:Retrospective study. SETTING:University-affiliated center. PATIENT(S):Women underwent PGD cycles of blastocyst biopsy an...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2016.01.011

    authors: Zhang S,Luo K,Cheng D,Tan Y,Lu C,He H,Gu Y,Lu G,Gong F,Lin G

    更新日期:2016-05-01 00:00:00

  • Introduction: An update on bone metabolism and osteoporosis.

    abstract::Osteoporosis continues to be a major public health challenge in both women and men. There are more than 2 million low-impact fractures in the United States every year, 39% of which occur in men. The mortality rate in the first year after hip fracture is estimated at 20% to 25% in women and is even higher in men. The g...

    journal_title:Fertility and sterility

    pub_type:

    doi:10.1016/j.fertnstert.2019.10.004

    authors: Schlaff WD

    更新日期:2019-11-01 00:00:00

  • A randomized, controlled trial of asoprisnil, a novel selective progesterone receptor modulator, in women with uterine leiomyomata.

    abstract:OBJECTIVE:To determine efficacy and safety of asoprisnil in patients with leiomyomata. DESIGN:Phase 2, multicenter, prospective, randomized, double-blind, placebo-controlled, parallel-group study. SETTING:Twenty-eight sites in the United States and 1 in Canada. PATIENT(S):One hundred twenty-nine women with leiomyoma...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.fertnstert.2006.11.094

    authors: Chwalisz K,Larsen L,Mattia-Goldberg C,Edmonds A,Elger W,Winkel CA

    更新日期:2007-06-01 00:00:00

  • Point of failure as a predictor of in vitro fertilization treatment discontinuation.

    abstract::Among 2,245 women, those who experienced a chemical pregnancy that failed to progress to a clinically recognized pregnancy or a spontaneous abortion on their first IVF cycle were more likely to discontinue IVF treatment than those whose first cycle ended before embryo transfer or who did not have a positive pregnancy ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.07.1732

    authors: Pearson KR,Hauser R,Cramer DW,Missmer SA

    更新日期:2009-04-01 00:00:00

  • Oxyphenbutazone--an adjuvant to be used in prevention of adhesions in operations for fertility.

    abstract::A laparotomy was performed in 40 rats and the cecum was subjected to a standardized trauma. Half the rats were treated with oxyphenbutazone in a dose of 40 mg/kg body weight daily for 14 days. The remaining 20 rats served as controls. All of the rats were killed 2 weeks after the laparotomy, and the number of intraper...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)42731-7

    authors: Larsson B,Svanberg SG,Swolin K

    更新日期:1977-08-01 00:00:00

  • Transvaginal natural orifice transluminal endoscopic surgery: a new approach to ovarian cystectomy.

    abstract:OBJECTIVE:To demonstrate a new approach for performing an ovarian cystectomy via transvaginal natural orifice transluminal endoscopic surgery (vNOTES) as an alternative for a laparoscopic ovarian cystectomy. DESIGN:Stepwise explanation of the technique using original video footage. SETTING:Hospital. PATIENT(S):Fourt...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2017.10.037

    authors: Baekelandt J

    更新日期:2018-02-01 00:00:00

  • Gamete donation: a question of anonymity.

    abstract::The key global issue surrounding gamete donation is not the well-rehearsed known vs. anonymous donation argument but rather one of providing patients with a flexible dual-track system (i.e., ability to know or not to know donor identity), complete with psychosocial support and education that enables them to make well-...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2005.07.1304

    authors: De Jonge C,Barratt CL

    更新日期:2006-02-01 00:00:00

  • Febrile morbidity following hysterosalpingography: identification of risk factors and recommendations for prophylaxis.

    abstract::Although previous large series have reported that from 0.3% to 1.3% of patients undergoing hysterosalpingography (HSG) develop infectious morbidity, our impression was that the incidence was higher among our patients. Therefore the records of 448 consecutive healthy women who underwent HSG were examined. Within 24 hou...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)44712-6

    authors: Stumpf PG,March CM

    更新日期:1980-05-01 00:00:00

  • Ovum donation--a simplified approach.

    abstract::To date, ovum donation (OD) has involved luteinizing hormone (LH) synchronization between recipient and donor for normally cycling women, and a complex steroid replacement regimen given on a sequential and incremental basis for women with primary or secondary ovarian failure. The authors designed a simple hormonal reg...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)59354-6

    authors: Serhal PF,Craft IL

    更新日期:1987-08-01 00:00:00