Novel protein RGPR-p117: its role as the regucalcin gene transcription factor.

abstract：:Expression of ErbB4 receptor is correlated with the incidence of non-metastatic types of human cancers, whereas the overexpression of other ErbB receptor families (ErbB1/EGFR, ErbB2 and ErbB3) is correlated to the formation of metastatic tumors. However, the molecular mechanism underlying this phenomenon has been uncl...

journal_title：Molecular and cellular biochemistry

authors： Yumoto N,Yu X,Hatakeyama M

更新日期：2006-04-01 00:00:00

abstract：:Transforming growth factor-β1 (TGF-β1) has been thought to play a major role during cardiac fibrosis in the development of diabetic cardiomyopathy, and cardiac fibrosis mainly as a result of an increase of collagen type III occurs in the human hearts with diabetes. Thrombospondin-1 (TSP-1) has been reported to activat...

journal_title：Molecular and cellular biochemistry

authors： Tang M,Zhou F,Zhang W,Guo Z,Shang Y,Lu H,Lu R,Zhang Y,Chen Y,Zhong M

更新日期：2011-01-01 00:00:00

abstract：:The antioxidant activity of anthocyanins has been well characterized in vitro; many cases has been postulated to provide an important exogenous mediator of oxidative stress in the gastrointestinal tract. The objective of this study was to evaluate the efficacy of anthocyanin protection against peroxyl radical (AAPH)-i...

journal_title：Molecular and cellular biochemistry

authors： Elisia I,Kitts DD

更新日期：2008-05-01 00:00:00

abstract：:Regulation of L-type Ca2+ channels is complex, because many factors, such as phosphorylation, divalent cations, and proteins, specified or unspecified, have been shown to affect the channel activities. An additional complication is that these factors interact with one another to achieve final outcomes. Recent molecula...

journal_title：Molecular and cellular biochemistry

authors： Yamaoka K,Kameyama M

更新日期：2003-11-01 00:00:00

abstract：:Insulin alone at concentrations of less than 1 to 5 uU/ml increased the enzyme activities of glycogen synthase, synthase phosphatase, phosphorylase, and phosphorylase phosphatase in hepatoma H4 cells in culture in the presence and absence of serum. Increase in total and active forms of glycogen synthase and phosphoryl...

journal_title：Molecular and cellular biochemistry

authors： Goheer MA,Larner J,Curnow RT

更新日期：1987-06-01 00:00:00

abstract：:Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are highly reactive transient chemical species, which play an important role in the etiology of tissue injury in rheumatoid arthritis (RA). The effects of milk extract of Semecarpus anacardium Linn. nut (SA) was studied on adjuvant arthritis in rats. Ar...

journal_title：Molecular and cellular biochemistry

authors： Ramprasath VR,Shanthi P,Sachdanandam P

更新日期：2005-08-01 00:00:00

abstract：:Differentiation of 3T3-L1 preadipocytes, induced by methyl-isobutylxanthine (MIX), dexamethasone (DEX), and insulin, results in cells with the morphological and biochemical characteristics of adipocytes. Following incubation of 3T3-L1 cells with MIX, DEX, and insulin, poly(ADP-ribose) synthetase activity decreased abr...

journal_title：Molecular and cellular biochemistry

authors： Pekala PH,Moss J

更新日期：1983-01-01 00:00:00

abstract：:We investigated the expression of the nuclear-encoded genes controlling the mitochondrial properties in the mouse gastrocnemius muscle to gain insight into the mitochondrial biogenesis that occurs during the muscle degeneration/regeneration induced by freezing. In addition, we tested whether the muscle regeneration is...

journal_title：Molecular and cellular biochemistry

authors： Wagatsuma A,Kotake N,Yamada S

更新日期：2011-03-01 00:00:00

abstract：:Mitochondrial respiratory rates and regulation by phosphate acceptors were studied on permeabilized fiber bundles differing in their myosin heavy chain profiles. The acceptor control ratio, an indicator of oxidation to phosphorylation coupling, and mitochondrial K(m) for ADP were the highest in type I, intermediate in...

journal_title：Molecular and cellular biochemistry

authors： Gueguen N,Lefaucheur L,Fillaut M,Herpin P

更新日期：2005-08-01 00:00:00

abstract：:Logistic complexities of heart transplantation embossed the necessity of utilizing novel methods, which enable heart regeneration. Human cardiosphere-derived cells (hCDCs) are taken into consideration as a promising cell resource in cell therapy in recent years. In this study, we designed an electrochemical stimulatio...

journal_title：Molecular and cellular biochemistry

authors： Nazari H,Kehtari M,Rad I,Ashtari B,Joghataei MT

更新日期：2020-07-01 00:00:00

abstract：:Both early diagnostic and prognostic assessment of the acute abdomen in preterm infants are hampered by the lack of a sensitive and specific parameter for intestinal injury. In this prospective clinical study we wanted to estimate the value of intestinal (I-) and liver (L-) fatty acid binding protein (FABP) in diagnos...

journal_title：Molecular and cellular biochemistry

authors： Guthmann F,Börchers T,Wolfrum C,Wustrack T,Bartholomäus S,Spener F

更新日期：2002-10-01 00:00:00

abstract：:Comparison of Ca2+ uptake by isolated mouse liver mitochondria, and mitochondria prepared from mastocytoma cells grown with and without N6,O2'-dibutyryladenosine 3',5' cyclic monophosphate (DB cyclic AMP) and theophylline showed several differences in their capacity to take up and retain calcium. In particular mitocho...

journal_title：Molecular and cellular biochemistry

authors： McHardy JE,Ralph RK

更新日期：1980-03-20 00:00:00

abstract：:Physiological, pharmacological, histochemical and biochemical studies indicate that dopamine receptors are heterogenous in the central nervous system with each individual functions. This review describes pharmacological and biochemical characteristics of dopamine receptors, particularly in canine caudate nucleus, whic...

journal_title：Molecular and cellular biochemistry

authors： Maeno H

更新日期：1982-03-19 00:00:00

abstract：:Frequent abnormalities in 7p12 locus in different tumors like lung cancer candidate this region for novel regulatory elements. MiRNAs as novel regulatory elements encoded within the human genome are potentially oncomiRs or miR suppressors. Here, we have used bioinformatics tools to search for the novel miRNAs embedded...

journal_title：Molecular and cellular biochemistry

authors： Hoballa MH,Soltani BM,Mowla SJ,Sheikhpour M,Kay M

更新日期：2018-07-01 00:00:00

abstract：:We have focused on the roles of PARP and poly(ADP-ribosyl)ation early in apoptosis, as well as during the early stages of differentiation-linked DNA replication. In both nuclear processes, a transient burst of PAR synthesis and PARP expression occurs early, prior to internucleosomal DNA cleavage before commitment to a...

journal_title：Molecular and cellular biochemistry

authors： Simbulan-Rosenthal CM,Rosenthal DS,Iyer S,Boulares H,Smulson ME

更新日期：1999-03-01 00:00:00

abstract：:The phosphorylation of rat cardiac microsomal proteins was investigated with special attention to the effects of okadaic acid (an inhibitor of protein phosphatases), inhibitor 2 of protein phosphatase 1 and inhibitor of cyclic AMP-dependent protein kinase (protein kinase A). The results showed that okadaic acid (5 mic...

journal_title：Molecular and cellular biochemistry

authors： Sulakhe PV,Vo XT,Morris TE,Pato MD,Khandelwal RL

更新日期：1997-10-01 00:00:00

abstract：:Cardiac hypertrophy in rats was produced by aortic banding for 6 weeks and regression of hypertrophy in these experimental animals was induced by administration of angiotensin converting enzyme inhibitor, enalapril (10 mg/kg/day) for 6 weeks. The left ventricular muscle mass and systolic pressure were decrease upon tr...

journal_title：Molecular and cellular biochemistry

authors： Makino N,Matsui H,Masutomo K,Hata T,Yanaga T

更新日期：1993-02-17 00:00:00

abstract：:We assessed whether aging augments left ventricular (LV) damage, remodeling, and dysfunction and alters expression of healing-specific-matricellular proteins (HSMPs), matrix metalloproteinases (MMPs) and other pertinent proteins after acute reperfused-ST-segment-elevation myocardial infarction (RSTEMI) in the dog mode...

journal_title：Molecular and cellular biochemistry

authors： Jugdutt BI,Palaniyappan A,Uwiera RR,Idikio H

更新日期：2009-02-01 00:00:00

abstract：:Myostatin belongs to the Transforming Growth Factor-beta (TGF-beta) superfamily and is expressed in developing and mature skeletal muscle. Biologically, the role of myostatin seems to be extremely well conserved during evolution since inactivating mutations in myostatin gene cause similar phenotype of heavy muscling i...

journal_title：Molecular and cellular biochemistry

authors： Jeanplong F,Sharma M,Somers WG,Bass JJ,Kambadur R

更新日期：2001-04-01 00:00:00

abstract：:Cellular FLICE-like inhibitory protein (Flip) is a negative regulator of nuclear factor κB signaling which has been shown previously to complicate with cardiac hypertrophy. In the present study, we tested the hypothesis that the knockout of Flip would increase cardiac hypertrophy in vivo and in vitro. The effects of F...

journal_title：Molecular and cellular biochemistry

authors： Huang Y,Wu L,Wu J,Li Y,Hou L

更新日期：2014-12-01 00:00:00

abstract：:Oxidative stress is recognized as one of the major wrongdoers in Parkinson's disease (PD) while glutathione S-transferase (GST), an endogenous antioxidant, protects from oxidative stress-induced neurodegeneration. Despite GST-pi (GST-π) encounters the toxic manifestations in PD, its role in zinc (Zn)-induced nigrostri...

journal_title：Molecular and cellular biochemistry

authors： Chauhan AK,Mittra N,Singh BK,Singh C

更新日期：2019-02-01 00:00:00

abstract：:We found out a new protein from natural actomyosin prepared from adductor muscle of Hokki clam, bivalve shell. We isolated this protein and determined some properties. It has a large molecular weight (230 kDa) and the star diagram of amino acid composition was very similar to that of paramyosin (110 kDa). When this pr...

journal_title：Molecular and cellular biochemistry

authors： Yazawa Y,Kamidochi M

更新日期：1999-01-01 00:00:00

abstract：:Several peptides derived from microtubule-associated tau protein, have been tested as substrates for glycogen synthase kinase 3 (GSK 3). In the absence of cofactors, GSK 3 can modify serines or threonines followed by prolines. In other cases, a phosphorylation in position +4 is required for the phosphorylation of thre...

journal_title：Molecular and cellular biochemistry

authors： Moreno FJ,Muñoz-Montaño JR,Avila J

更新日期：1996-12-06 00:00:00

abstract：:The aim of this study was to elucidate the effects of natural vanadium-containing Jeju ground water on glucose uptake in L6 myotubes and adipogensesis in 3T3 L1 cells. The Jeju ground water samples containing vanadium components were designated as S1 (8.0 ± 0.9 μg/l), S2 (24.0 ± 2.0 μg/l), and S3 (26.0 ± 2.0 μg/l), re...

journal_title：Molecular and cellular biochemistry

authors： Hwang SL,Chang HW

更新日期：2012-01-01 00:00:00

abstract：:Parkinson disease (PD) is a neurodegenerative disease characterized by progressive dopaminergic neurodegeneration in the substantia nigra pars compacta (SNc) area. The present study was undertaken to evaluate the neuroprotective effect of β-caryophyllene (BCP) against rotenone-induced oxidative stress and neuroinflamm...

journal_title：Molecular and cellular biochemistry

authors： Ojha S,Javed H,Azimullah S,Haque ME

更新日期：2016-07-01 00:00:00

abstract：:Oxidative stress is one of the mechanisms involved in the acute carbon tetrachloride (CCl4)-induced hepatotoxicity. Since 4-hydroxy-2,2,6,6-tetramethylpiperidin-1-oxyl, known as tempol, has powerful antioxidant properties, we investigated its potential hepatoprotective effects and the underlying mechanisms that may ad...

journal_title：Molecular and cellular biochemistry

authors： Abouzied MM,Eltahir HM,Taye A,Abdelrahman MS

更新日期：2016-01-01 00:00:00

abstract：:Kawasaki disease is an immune-mediated acute, systemic vasculitis and is the leading cause of acquired heart disease in children in the developed world. Bifidobacterium (BIF) is one of the dominant bacteria in the intestines of humans and many mammals and is able to adjust the intestinal flora disorder. The Caco-2 cel...

journal_title：Molecular and cellular biochemistry

authors： Nie N,Bai C,Song S,Zhang Y,Wang B,Li Z

更新日期：2020-01-01 00:00:00

abstract：:The pathophysiologic importance of insulin resistance in diseases such as obesity and diabetes mellitus has led to great interest in defining the mechanism of insulin action as well as the means to overcome the biochemical defects responsible for the resistance. Vanadium compounds have been discovered to mimic many of...

journal_title：Molecular and cellular biochemistry

authors： Fantus IG,Tsiani E

更新日期：1998-05-01 00:00:00

abstract：:Ischemia/reperfusion injury causes cardiomyocyte apoptosis, ventricular remodeling, leading to a dilated heart. Hypoxia is one of the causes involved in ischemia damage, and BNIP3 is a hypoxia-inducible marker and also a sensor to induce mitochondria-dependent apoptosis. Recent reports discussed ablating BNIP3 can res...

journal_title：Molecular and cellular biochemistry

authors： Weng YJ,Kuo WW,Kuo CH,Tung KC,Tsai CH,Lin JA,Tsai FJ,Hsieh DJ,Huang CY,Hwang JM

更新日期：2010-12-01 00:00:00

abstract：:The marine blood clam species Anadara granosa (L) belong to arcidae, a family with some extraordinary haematological features. The plasma of this species exhibited strong haemagglutinating activities, from which a galactosyl binding lectin, Anadarin P, was purified in a single step affinity chromatography using Sephar...

journal_title：Molecular and cellular biochemistry

authors： Dam TK,Sarkar M,Ghosal J,Choudhury A

更新日期：1992-11-04 00:00:00