Degeneration of nuclei and mitochondria in human hairs.

Abstract:

:It is generally accepted that nuclei degrade in developing hair shafts but the point at which such occurs has not been investigated. The fate of mitochondria in the keratinizing hair shaft has been less clear. This study uses transmission electron microscopy to investigate when nuclei and mitochondria are no longer visible in the developing hair shaft. Serial sections were obtained from anagen head hairs absent follicles in order to determine the sequence of degradation of nuclei and mitochondria in the hair shaft by starting at the root bulb and proceeding toward the hair tip. It was demonstrated that nuclei and mitochondria become invisible in the keratinizing hair shaft at about the same time. This was found to occur fairly early in the process at the level of the hair shaft where the hair cuticle becomes permanent.

journal_name

J Forensic Sci

authors

Linch CA

doi

10.1111/j.1556-4029.2008.00972.x

subject

Has Abstract

pub_date

2009-03-01 00:00:00

pages

346-9

issue

2

eissn

0022-1198

issn

1556-4029

pii

JFO972

journal_volume

54

pub_type

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