Abstract:
:The objective of this article is to present a set of methods for constructing realistic computational models of cardiac structure from high-resolution structural and diffusion tensor magnetic resonance images and to demonstrate the applicability of the models in simulation studies. The structural image is segmented to identify various regions such as normal myocardium, ventricles, and infarct. A finite element mesh is generated from the processed structural data, and fiber orientations are assigned to the elements. The Purkinje system, when visible, is modeled using linear elements that interconnect a set of manually identified points. The methods were applied to construct 2 different models; and 2 simulation studies, which demonstrate the applicability of the models in the analysis of arrhythmia and defibrillation, were performed. The models represent cardiac structure with unprecedented detail for simulation studies.
journal_name
J Electrocardioljournal_title
Journal of electrocardiologyauthors
Vadakkumpadan F,Rantner LJ,Tice B,Boyle P,Prassl AJ,Vigmond E,Plank G,Trayanova Ndoi
10.1016/j.jelectrocard.2008.12.003subject
Has Abstractpub_date
2009-03-01 00:00:00pages
157.e1-10issue
2eissn
0022-0736issn
1532-8430pii
S0022-0736(08)00491-3journal_volume
42pub_type
杂志文章abstract:BACKGROUND:Hibernating myocardium develops inhomogeneity in myocardial sympathetic innervation with spontaneous sudden cardiac death (SCD) because of ventricular fibrillation (VF). The triggers and prodromal arrhythmias initiating SCD in this substrate are unknown. METHODS:Swine chronically instrumented with a proxima...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2006.05.026
更新日期:2006-10-01 00:00:00
abstract::In a patient with Wolff-Parkinson-White syndrome and an inferior-posterior bypass tract, transient restoration of normal conduction occurred during an attack of angina. The ECG pattern of inferior posterior ischemia was present when the conduction was normal. Thallium scintigraphy showed a reversible posterolateral pe...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(90)90165-x
更新日期:1990-07-01 00:00:00
abstract::Signal-averaged electrocardiogram (ECG) variables were analyzed in 81 patients with ventricular tachyarrhythmia and nonischemic heart disease using the ART LVP 101 EPX system (Austin, TX): 15 ventricular tachycardia patients with arrhythmogenic right ventricular dysplasia (ARVD), 7 ventricular tachycardia patients wit...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(94)80091-x
更新日期:1994-01-01 00:00:00
abstract::The left ventricle (LV) plays a central role in the maintenance of health of children and adults due to its role as the major pump of the heart. In cases of LV dysfunction, a significant percentage of affected individuals develop signs and symptoms of congestive heart failure, leading to the need for therapeutic inter...
journal_title:Journal of electrocardiology
pub_type: 杂志文章,评审
doi:10.1054/jelc.2001.28859
更新日期:2001-01-01 00:00:00
abstract:BACKGROUND:There is a controversy regarding the association between QRS width and ventricular arrhythmias (VAs). We hypothesized that predictive value of the QRS width could be improved if QRS width were considered in the context of the sum magnitude of the absolute QRST integral in 3 orthogonal leads sum absolute QRST...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2010.07.013
更新日期:2010-11-01 00:00:00
abstract::The American College of Cardiology recommends that patients with high risk acute myocardial infarction (AMI) be triaged to hospitals with percutaneous transluminal coronary angioplasty capability. However, there are no prehospital triage criteria to select candidates for bypassing community hospitals and being taken d...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2000.20299
更新日期:2000-01-01 00:00:00
abstract::Brugada phenocopies are clinical entities characterized by electrocardiographic patterns that are identical to true Brugada syndrome, but are elicited by a number of clinical circumstances. ECG normalizes upon resolution of underlying condition, family history of arrhythmic syncope or ventricular arrhythmias is strict...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2019.04.003
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Temporary-permanent pacemakers [TPPM] are externally placed permanent generators attached to active fixation transvenous leads. TPPM can be used as an alternative to standard temporary pacing leads when placement of a permanent pacemaker is contraindicated. We sought to determine the incidence and risk facto...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2016.05.004
更新日期:2016-07-01 00:00:00
abstract::In eighteen patients with atrioventricular conduction disturbance, His bundle electrograms were studied via the arm vein. A 6F Berkovits-Castellanos USCI hexapolar electrode catheter was introduced into the right atrium and looped across the tricuspid valve in a "golf club" shape. The main aim was to leave the two dis...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(81)80046-5
更新日期:1981-01-01 00:00:00
abstract::The numerous criteria proposed for the electrocardiographic (ECG) diagnosis of biventricular hypertrophy (BVH) suffer from inadequate correlative data. We used two-dimensional (2D) echocardiography to identify BVH and analyzed the ECG patterns in these patients. The study group had 69 such patients with BVH and the co...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:
更新日期:1999-07-01 00:00:00
abstract:BACKGROUND:Displacement of ECG leads can result in unwarranted findings. We assessed the frequency of Brugada-type patterns in athletes when precordial leads were purposely placed upward. METHODS:Four hundred ninety-one collegiate athletes underwent two ECGs: one with standard leads, one with V1 and V2 along the 2nd i...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2013.08.014
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:Recent research has established that a tall R-wave in V1 indicates lateral wall involvement in non-anterior wall myocardial infarction (MI). The objective of this study was to assess the value of the admission electrocardiogram (ECG) to predict R-waves and consequently lateral wall damage in the late phase of n...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2015.02.005
更新日期:2015-07-01 00:00:00
abstract::Hypertrophic cardiomyopathy (HCM) have been reported to display impaired heart rate variability, although little is known regarding its prognostic value. By using fast Fourier transformation of 24-hour Holter recordings in 73 HCM patients at a stable clinical condition, we computed 4 spectral components: very low freq...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2003.08.005
更新日期:2003-10-01 00:00:00
abstract::One-to-two atrioventricular conduction, ie, the double response to a single sinus or atrial impulse, resulting in two QRS complexes for one P wave, is a rare manifestation of dual atrioventricular (AV) nodal pathways. This report describes the case of a 61-year-old woman with continuous episodes of supraventricular ta...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(99)90005-5
更新日期:1999-10-01 00:00:00
abstract::A method has been developed for establishing a "University Without Walls" for the purpose of studying the relationship between electrocardiographic estimation and magnetic resonance imaging measurements of myocardial infarct size. The research team includes faculty and students from 4 medical centers, with expertise e...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1054/jelc.2001.28810
更新日期:2001-01-01 00:00:00
abstract::The ability of ECG-VCG to predict the severity of postinfarction LV asynergy was evaluated in 152 patients with previous myocardial infarction who underwent left cineventriculography in the right anterior oblique view. Various ECG and VCG signs were examined in order to predict the existence of severe asynergy in gene...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(84)81092-4
更新日期:1984-04-01 00:00:00
abstract::The purpose of this experiment is to study the possibility of intra-QRS high-frequency electrocardiographic (HFECG) changes for the evaluation of and recovery from myocardial ischemia in both the time-domain and spectral-turbulence analyses on the signal-averaged ECG using the Holter ECG monitoring (Holter SAECG) syst...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(95)80064-6
更新日期:1995-01-01 00:00:00
abstract::Atrial arrhythmias are diagnosed on the basis of the analysis of P wave morphology, timing and rate, the surface electrocardiogram, and intracardiac recordings. Recent intracardiac studies have demonstrated dissimilar atrial rhythms with direct intra-atrial recordings, the former otherwise not evident on the surface E...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(91)90010-j
更新日期:1991-04-01 00:00:00
abstract::An analytical study was performed to estimate the magnitude of the visual Q wave duration bias produced by pressurized ink round stylus electrocardiographic (ECG) recorders. With a paper speed of 25 mm/sec and the ECG tracing width of 0.25 mm, the visually measured Q waves are on the average 8 msec too short. The corr...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(78)80137-x
更新日期:1978-10-01 00:00:00
abstract::The authors investigated the usefulness of the Karhunen-Loeve technique applied to body surface maps to study regional cardiac excitation. Eigenvectors were derived from the body surface potential maps of 120 healthy adults using the Karhunen-Loeve expansion theory. Then, in the maps of various types of ventricular hy...
journal_title:Journal of electrocardiology
pub_type: 临床试验,杂志文章
doi:10.1016/0022-0736(90)90148-u
更新日期:1990-01-01 00:00:00
abstract::We are reporting a series of 13 out of a total of 16 patients in whom sinus nodal activity was recorded with the use of intra-atrial electrodes, during diagnostic His-bundle electrocardiography investigations. The protocol consisted of the simultaneous monitoring of the following intra-atrial points: high right atrium...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(79)80002-3
更新日期:1979-10-01 00:00:00
abstract::Forty-three patients with their first acute inferior wall myocardial infarction (IWMI) were divided into three groups according to the R/Q ratio in standard lead II. This was done to correlate these groups with the characteristic course of electrocardiographic stages. The R/Q ratio was measured on the ninth day of fol...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/0022-0736(88)90105-7
更新日期:1988-11-01 00:00:00
abstract::A rigorous mathematical analysis of Electrocardiogram (ECG) data is presented in this paper, as a decision support system for ECG interpretation. The mathematical analysis: provides a new insight to the ECG data, provides flexibility for future understanding of the heart system or the ECG, and avoids the need of measu...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::Using standard biopolar, temporary pacing catheters, thresholds were measured in four configurations: (1) bipolar (distal electrode negative, proximal electrode positive); (2) distal unipolar (distal electrode negative, right arm electrode positive); (3) proximal unipolar (proximal electrode negative, right arm electr...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(76)80077-5
更新日期:1976-04-01 00:00:00
abstract:UNLABELLED:The verapamil-sensitive Belhassen tachycardia is a ventricular reentrant tachycardia, involving left-sided Purkinje fibers and abnormal Purkinje or myocardial tissue. Ablation is feasible, targeting a diastolic fascicular potential in the apical left ventricle. CASE REPORT:We report on a 13-year-old girl wi...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2011.02.003
更新日期:2011-11-01 00:00:00
abstract::An inexpensive system was developed for automated on-line analysis of ST segment heights, Q, R, and S heights and areas under these peaks, using an LSI-11 microcomputer. System accuracy was evaluated using a computer graphics technique which enabled magnification and labelling of the computed peaks on 60 maps from 17 ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(82)80032-0
更新日期:1982-01-01 00:00:00
abstract::RBBB tachycardia with NW axis is considered to be VT unless proved otherwise. However underlying conduction system disease can produce electrocardiographic patterns suggestive of bundle branch block with extreme left axis which can cause difficulty in differentiating VT from SVT as in this case. ...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2017.08.036
更新日期:2018-01-01 00:00:00
abstract::To elucidate the electrocardiographic (ECG) characteristics of dilated cardiomyopathy (DCM), the authors analyzed the 12-lead ECGs and echocardiograms in 45 patients with DCM, 54 patients with left ventricular (LV) dilatation secondary to valvular heart disease (VHD), 101 hypertensive patients with LV hypertrophy, and...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/s0022-0736(05)80270-5
更新日期:1994-10-01 00:00:00
abstract:INTRODUCTION:Measures of heart rate variability (HRV) can be divided in time domain and frequency domain parameters. It is frequently ignored that estimation of frequency-domain parameters is a 2-step procedure where statistical error from the first step (spectral estimation) is neglected in subsequent analyses. METHO...
journal_title:Journal of electrocardiology
pub_type: 杂志文章
doi:10.1016/j.jelectrocard.2008.02.014
更新日期:2008-07-01 00:00:00
abstract::Postoperative atrial fibrillation is common after cardiac surgery. Prediction of which patients will develop postoperative atrial fibrillation would be clinically useful. Increased P-wave duration, suggesting atrial conduction delay and measured from preoperative electrocardiograms, predicts postoperative atrial fibri...
journal_title:Journal of electrocardiology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.jelectrocard.2004.01.003
更新日期:2004-04-01 00:00:00