A case of natural killer cell lymphoma presenting with bilateral pleural effusions and hemophagocytic lymphohistocytosis.

abstract：BACKGROUND:Partial nephrectomy (NSS) for unilateral nephroblastoma may be beneficial, although in case of regional lymph node (LN) involvement, radiotherapy counteracts the functional benefit of NSS. The aim is to verify whether decrease of tumor volume under preoperative chemotherapy implies clearance of regional LN. ...

journal_title：Pediatric blood & cancer

authors： Godzinski J,van Tinteren H,de Kraker J,Graf N,Bergeron C,Heij H,von Schweinitz D,Fuchs J,Cecchetto G,Audry G,Gauthier F,Sandstedt B,SIOP Nephroblastoma Trial & Study Committee.

更新日期：2011-12-15 00:00:00

abstract：:We evaluated the effects of body mass index (BMI) on the risk of thromboembolism (TE) in children (<18 years) with hematological malignancies during the period 1990-2009 (n = 359). Obesity was prevalent in 12% of patients: 6% versus 17% prior to and after the year 2000 (P = 0.02). Sixty-one (17%) patients developed TE...

journal_title：Pediatric blood & cancer

authors： Tuckuviene R,Christensen AL,Chan AK,Athale U

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Children with cancer may be at an increased risk of infection with hepatitis B virus (HBV) when levels of hepatitis B antibodies are reduced owing to chemotherapy-induced immunosuppression. This study evaluated the changes in HBV antibody status and HBV infections after chemotherapy in children with acute ly...

journal_title：Pediatric blood & cancer

authors： Choi YB,Lee NH,Yi ES,Kim YJ,Koo HH

更新日期：2019-12-01 00:00:00

abstract：:Opsoclonus, myoclonus, ataxia syndrome (OMA) is a severe neurologic disorder often associated with neuroblastoma. It is challenging to treat and can have long-term neurologic sequelae. Current recommended therapies include intravenous immunoglobulin, corticosteroids, rituximab, and chemotherapy (cyclophosphamide). We ...

journal_title：Pediatric blood & cancer

authors： Johnston DL,Murray S,Irwin MS,Doyle J,Schechter T

更新日期：2018-08-01 00:00:00

abstract：:Bereaved families fear their child being forgotten by those who knew their loved child, including their child's oncology team. Thoughtfully timed, family-centric condolences shared by pediatric oncology team members have the potential to extend our compassion and kindness toward a family during the darkness of grief. ...

journal_title：Pediatric blood & cancer

authors： Weaver MS,Lichtenthal WG,Larson K,Wiener L

更新日期：2019-02-01 00:00:00

abstract：:Optic pathway gliomas represent approximately 5% of all pediatric intracranial tumors. While these tumors are most frequently low grade astrocytomas, they follow a highly variable clinical course, and accordingly, there is much debate regarding their optimal management. Their propensity to occur in very young children...

journal_title：Pediatric blood & cancer

authors： Jahraus CD,Tarbell NJ

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The aim of the study was to investigate factors affecting response to everolimus, a mammalian-target-of-rapamycin (mTOR) inhibitor, of subependymal giant cell astrocytomas (SEGA) in patients with tuberous sclerosis complex (TSC). METHODS:The study group consisted of 15 children with a diagnosis of TSC-relat...

journal_title：Pediatric blood & cancer

authors： Trelinska J,Dachowska I,Kotulska K,Baranska D,Fendler W,Jozwiak S,Mlynarski W

更新日期：2015-04-01 00:00:00

abstract：:The objective of this study is to determine the prevalence of adherence to daily medications among children with sickle cell disease (SCD). Prescription records for 12 months were obtained from participants who had insurance in a Medicaid-based single health maintenance organization. Adherence was measured as a ratio ...

journal_title：Pediatric blood & cancer

authors： Patel NG,Lindsey T,Strunk RC,DeBaun MR

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:We sought to determine the risk of bacteremia in a cohort of outpatient febrile nonneutropenic pediatric oncology patients and to assess clinical characteristics that may influence decisions regarding empiric antibiotic therapy. PROCEDURE:A single institution retrospective cohort study was performed of outp...

journal_title：Pediatric blood & cancer

authors： Kelly MJ,Vivier PM,Panken TM,Schwartz CL

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Patients with sickle cell anemia (SCA) experience a broad range of psychiatric disorders, placing them at risk for more complicated and longer hospitalizations for vaso-occlusive crises (VOC). The current study examined the frequency of psychiatric disorders in SCA patients (ages birth to 20 years) admitted ...

journal_title：Pediatric blood & cancer

authors： Myrvik MP,Campbell AD,Davis MM,Butcher JL

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Ispinesib is a highly specific inhibitor of kinesin spindle protein (KSP, HsEg5), a mitotic kinesin required for separation of the spindle poles. Here we report the activity of ispinesib against the in vitro and in vivo panels of the Pediatric Preclinical Testing Program (PPTP). PROCEDURES:Ispinesib was tes...

journal_title：Pediatric blood & cancer

authors： Carol H,Lock R,Houghton PJ,Morton CL,Kolb EA,Gorlick R,Reynolds CP,Maris JM,Keir ST,Billups CA,Smith MA

更新日期：2009-12-15 00:00:00

abstract：BACKGROUND:To evaluate efficacy, pharmacokinetics (PK) and pharmacodynamics of single-agent everolimus in pediatric patients with radiographically progressive low-grade glioma (LGG). METHODS:Everolimus was administered at 5 mg/m2 once daily as a tablet or liquid for a planned 48-week duration or until unacceptable tox...

journal_title：Pediatric blood & cancer

authors： Wright KD,Yao X,London WB,Kao PC,Gore L,Hunger S,Geyer R,Cohen KJ,Allen JC,Katzenstein HM,Smith A,Boklan J,Nazemi K,Trippett T,Karajannis M,Herzog C,Destefano J,Direnzo J,Pietrantonio J,Greenspan L,Cassidy D,Sch

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:An adapted LMB 96 derived protocol for B-cell non-Hodgkin lymphoma (NHL) was implemented at the pediatric oncology unit of the Children Welfare Teaching Hospital in Baghdad (Iraq) from 2000 to present. The purpose was to evaluate the feasibility and efficacy of this intensive therapeutic regimen in a limited...

journal_title：Pediatric blood & cancer

authors： Moleti ML,Al-Hadad SA,Al-Jadiry MF,Al-Darraji AF,Al-Saeed RM,De Vellis A,Piciocchi A,Uccini S,Foà R,Testi AM

更新日期：2011-04-01 00:00:00

abstract：:Angiotensin converting enzyme (ACE) gene insertion(I)/deletion(D) polymorphism influences the outcome of a number of cardiovascular diseases. ACE I/D polymorphism was investigated by PCR in 207 pediatric cancer patients and 144 controls. ACE I/D distribution of patients and controls was similar. The frequency of the D...

journal_title：Pediatric blood & cancer

authors： Bárdi E,Jenei C,Kiss C

更新日期：2005-08-01 00:00:00

abstract：:Optic pathway gliomas (OPG) in neurofibromatosis type 1 (NF1) usually remain localized to the anterior visual pathway. However, a small number can demonstrate widespread dissemination. We describe three children with NF1 OPGs and extensive central nervous system involvement. In one case, a postmortem examination revea...

journal_title：Pediatric blood & cancer

authors： Shaikh F,Johnston D,Michaud J,Hurteau J,Vassilyadi M,Keene D

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Alveolar soft part sarcomas (ASPS) are generally chemo- and radio-resistant mesenchymal tumours, with no standardized treatment guidelines. We describe the clinical behaviour of paediatric ASPS and compare these features to previously reported adult series. PATIENTS AND METHODS:The clinical data of 51 child...

journal_title：Pediatric blood & cancer

authors： Orbach D,Brennan B,Casanova M,Bergeron C,Mosseri V,Francotte N,Van Noesel M,Rey A,Bisogno G,Pierron G,Ferrari A

更新日期：2013-11-01 00:00:00

abstract：:Spermatogonial stem cells open novel strategies for preservation of testicular tissue and fertility preservation in boys and men exposed to gonadotoxic therapies. This review provides an update on the physiology of spermatogonial stem cells in rodent and primate testes. Species-specific differences must be considered ...

journal_title：Pediatric blood & cancer

authors： Schlatt S,Ehmcke J,Jahnukainen K

更新日期：2009-08-01 00:00:00

abstract：:Malignant mesothelioma (MM) is a highly aggressive malignancy that is extremely rare in children. This case report documents a 7-year-old male without previous asbestos exposure with peritoneal MM that initially responded to chemotherapy with cisplatin and gemcitabine but ultimately metastasized to his chest. He was d...

journal_title：Pediatric blood & cancer

authors： Sugalski A,Davis M,Prasannan L,Saldivar V,Hung JY,Tomlinson GE

更新日期：2013-01-01 00:00:00

abstract：:Deferasirox (Exjade®, Novartis) is a widely used oral iron chelator for the treatment of patients with iron overload due to chronic transfusion therapy for diseases such as β-thalassemia and sickle cell disease. Renal side effects of deferasirox are common and include non-progressive increases in serum creatinine, how...

journal_title：Pediatric blood & cancer

authors： Rheault MN,Bechtel H,Neglia JP,Kashtan CE

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Fever in severe chemotherapy-induced neutropenia (FN) is the most frequent manifestation of a potentially lethal complication of current intensive chemotherapy regimens. This study aimed at establishing models predicting the risk of FN, and of FN with bacteremia, in pediatric cancer patients. METHODS:In a s...

journal_title：Pediatric blood & cancer

authors： Wicki S,Keisker A,Aebi C,Leibundgut K,Hirt A,Ammann RA

更新日期：2008-12-01 00:00:00

abstract：:Treatment recommendations for endemic Burkitt lymphoma (BL) in settings with only minimum requirements for curative treatment (PODC setting 1) are described. The reported cure rate for endemic BL is usually <50%. Facilities within setting 1 differ. Three treatment schedules are proposed based on: (1) when accurate sta...

journal_title：Pediatric blood & cancer

authors： Hesseling P,Israels T,Harif M,Chantada G,Molyneux E,Pediatric Oncology in Developing Countries.

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:A lack of access to methotrexate levels is common in low- and middle-income countries (LMIC), relevant for 80% of children with cancer worldwide. We evaluated whether high-dose methotrexate (HD-MTX) can be administered safely with extended hydration and leucovorin rescue, with monitoring of serum creatinine ...

journal_title：Pediatric blood & cancer

authors： Vaishnavi K,Bansal D,Trehan A,Jain R,Attri SV

更新日期：2018-12-01 00:00:00

abstract：:Hospital-based home care (HBHC) is widely applied in Pediatric Oncology. We reviewed the potential effect of HBHC on children's physical health and risk of adverse events, parental and child satisfaction, quality of life of children and their parents, and costs. A search of PubMed, CINAHL, and EMBASE led to identifica...

journal_title：Pediatric blood & cancer

authors： Hansson H,Hallström I,Kjaergaard H,Johansen C,Schmiegelow K

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:PG11047 is a novel conformationally restricted analog of the natural polyamine, spermine that lowers cellular endogenous polyamine levels and competitively inhibits natural polyamine functions leading to cancer cell growth inhibition. The activity of PG11047 was evaluated against the PPTP's in vitro and in v...

journal_title：Pediatric blood & cancer

authors： Smith MA,Maris JM,Lock R,Kolb EA,Gorlick R,Keir ST,Carol H,Morton CL,Reynolds CP,Kang MH,Houghton PJ

更新日期：2011-08-01 00:00:00

abstract：:We describe a child with dyserythropoietic anemia, thrombocytosis, functional platelet defect, and megakaryocyte dysplasia. We show that (i) this constellation of hematopoietic abnormalities was due to a germline mutation within the 5' untranslated region (5'UTR) of globin transcription factor 1 (GATA1); (ii) the muta...

journal_title：Pediatric blood & cancer

authors： Zucker J,Temm C,Czader M,Nalepa G

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:The Paediatric Oncology Centres (POCs) treating childhood cancer in South East England produce unified supportive care guidelines for use in the secondary pediatric (shared care) units. This study evaluated the adherence to current guidelines for febrile neutropenia (FN) and documented outcome in terms of ba...

journal_title：Pediatric blood & cancer

authors： Duncan C,Chisholm JC,Freeman S,Riley U,Sharland M,Pritchard-Jones K

更新日期：2007-10-15 00:00:00

abstract：:Wilms tumor (WT) is the most common primary renal tumor in childhood. The occurrence of WT in patients with growth retardation, mental retardation and central nervous system abnormalities in association with premature chromatid separation (PCS) and mosaic variegated aneuploidy has been previously described in only 10 ...

journal_title：Pediatric blood & cancer

authors： Sari N,Akyuz C,Aktas D,Gumruk F,Orhan D,Alikasifoglu M,Aydin B,Alanay Y,Buyukpamukcu M

更新日期：2009-08-01 00:00:00

abstract：:To search for novel mechanisms that contribute to the pathophysiology of idiopathic thrombocytopenic purpura (ITP), we determined the whole blood gene expression profile in five ITP patients and five control samples. Using DNA microarrays that contained 24,473 unique putative genes, we found 176 cDNAs that were strong...

journal_title：Pediatric blood & cancer

authors： Sood R,Wong W,Jeng M,Zehnder JL

更新日期：2006-10-15 00:00:00

abstract：:This is the case report of a 14-year young female who was diagnosed with solitary bone plasmacytoma (SBP) of proximal tibia and was treated by local involved field radiotherapy. We present the clinical, radiological and pathological findings of the case and review of the available treatment options and prognosis of th...

journal_title：Pediatric blood & cancer

authors： Kumar P,Sharma SC,Saikia UN,Kumar N,Vyas S,Angurana SL

更新日期：2011-01-01 00:00:00

abstract：:Childhood, adolescent, and young adult (CAYA) cancer survivors may be at risk for a severe course of COVID-19. Little is known about the clinical course of COVID-19 in CAYA cancer survivors, or if additional preventive measures are warranted. We established a working group within the International Late Effects of Chil...

journal_title：Pediatric blood & cancer

authors： Verbruggen LC,Wang Y,Armenian SH,Ehrhardt MJ,van der Pal HJH,van Dalen EC,van As JW,Bardi E,Baust K,Berger C,Castagnola E,Devine KA,Gebauer J,Marchak JG,Glaser AW,Groll AH,Haeusler GM,den Hartogh J,Haupt R,Hjorth L

更新日期：2020-12-01 00:00:00