Abstract：
PURPOSE:The prognosis for stage III melanoma patients is mixed, and there is need for new prognostic factors to be incorporated into a revision of melanoma TNM staging. We analyzed the possible role of the timing of lymph node involvement as an important prognostic factor. METHODS:Among 249 melanoma patients who underwent ilioinguinal lymphadenectomy, a group of 185 patients with a thick (>4mm) melanoma and full clinical data available was analyzed. The mean depth of invasion was 5.85 mm; the tumor was ulcerated in 67 cases (36.2%); and Clark V was diagnosed in 82 patients (44.3%). The median interval between primary excision and the time of lymphadenectomy was 11.1 months. RESULTS:Recurrent disease was reported in 150 of 185 patients. The first sites of recurrence were the skin in 15.7%, lymph nodes in 13.5%, and distant metastases in 28.7%; the remaining 43 patients (23.2%) had multifocal recurrences. In all, 35 patients (18.9%) were disease-free. Skip metastases (positive iliac and negative inguinal lymph nodes) were found in 26 patients (14%). Multivariate Cox analysis showed that only the time between the first surgery and lymphadenectomy and the number of involved nodes were significant predictors of survival. Relative risk of death was 5.2 times higher for patients who had simultaneously undergone lymphadenectomy (compared to lymph dissection performed >1 year after primary excision) and about 2.7 times higher for those with more regionally advanced disease (pN3 vs. pN1). CONCLUSIONS:The long disease-free interval before the development of lymph node metastases and before node dissection is a favorable prognostic factor independent of other well known parameters.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Herman K,Wysocki WM,Skotnicki P,Tabor J,Luczyńska E,Komorowski ALdoi
10.1007/s00268-008-9895-zsubject
Has Abstractpub_date
2009-03-01 00:00:00pages
469-74issue
3eissn
0364-2313issn
1432-2323journal_volume
33pub_type
杂志文章abstract：:Acute acalculous cholecystitis (AAC) is a well known complication in severely traumatized patients. Existing data of AAC originate from retrospective analyses and episodic case reports. In a prospective study 45 polytraumatized patients admitted to our intensive care unit from January 1989 to June 1990 were clinically...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067089
更新日期：1992-11-01 00:00:00
abstract：PURPOSE:There is no standardized treatment for patients with chemo-resistant or recurrent advanced ovarian cancer. Locoregional treatments combining cytoreductive surgery and intraperitoneal chemohyperthermia (HIPEC) may improve survival for locoregional disease. PATIENTS AND METHODS:A prospective single center study ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9146-8
更新日期：2007-09-01 00:00:00
abstract：INTRODUCTION:Covid-19 has had a significant impact on all aspects of health care. We aimed to characterise the trends in emergency general surgery at a district general hospital in Scotland. METHODS:A prospective cohort study was performed from 23/03/20 to 07/05/20. All emergency general surgery patients were included...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05760-3
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to describe the perioperative and long-term results of carotid endarterectomy (CEA) in patients aged 60 or less and compare them to patients of more advanced age in a retrospective single-centre case-control study. METHODS:From January 1996 to December 2014, 5893 consecutive CEAs wer...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4133-1
更新日期：2018-01-01 00:00:00
abstract：:Quality of life is an important outcome measure following surgery for ulcerative colitis. Quality of life incorporates not only the physical or functional outcome; it also considers the emotional and social well-being of patients. Quality of life may be measured using disease-specific or generic quality of life measur...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900400
更新日期：1998-04-01 00:00:00
abstract：:Inflammation is an essential component of the first phase of anastomotic wound healing, and it is suppressed by corticosteroids. The anti-inflammatory effect of corticosteroids is largely responsible for the impairment of wound healing in bowel anastomosis. It has been reported that local application of granulocyte-ma...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6505-3
更新日期：2002-10-01 00:00:00
abstract：BACKGROUND:There have been no reports on the impact of preoperative biliary MRSA infection on the outcome of major hepatectomy. The aim of this study was to review the surgical outcome of patients who underwent hepatobiliary resection after biliary drainage and to evaluate the impact of preoperative biliary MRSA infect...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-0990-1
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:Alternative methods to overcome limitations of electromyogram (EMG) tube applied for intraoperative neuromonitoring (IONM) of recurrent laryngeal nerve (RLN) during thyroidectomy have been introduced. In this study, we evaluated the feasibility of adhesive skin electrodes for IONM of RLN in patients who unde...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05208-3
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Assessment of preoperative physiological status is crucial for optimizing clinical outcomes in patients undergoing surgery for esophageal carcinoma (EC). We aimed to evaluate the prognostic impact of pulmonary dysfunctions and their relationships with other physiological factors, especially sarcopenia, in EC...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05450-0
更新日期：2020-07-01 00:00:00
abstract：:Eighty patients undergoing cholecystectomy were either assigned deliberately (n = 30) or randomized (n = 50) to drainage (n = 38) or nondrainage (n = 42). Subhepatic collections were seen on ultrasonography (US) after 48 to 72 hours in 12 of 35 patients with drainage and 24 of 42 patients without drainage (p < 0.05). ...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01655718
更新日期：1993-01-01 00:00:00
abstract：:Inflammatory breast cancer (IBC) is the most aggressive form of locally advanced breast cancer. It can be diagnosed based on a clinical or pathologic basis. We evaluated the usefulness of (18)F-fluorodeoxyglucose-positron emission tomography (FDG-PET) scans for diagnosing and staging IBC. We retrospectively reviewed t...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-6893-z
更新日期：2003-10-01 00:00:00
abstract：BACKGROUND:The Acute Care Surgery (ACS) model was developed as a dedicated service for the provision of 24/7 nontrauma emergency surgical care. This systematic review investigated which components are essential in an ACS model and the state of implementation of ACS models worldwide. METHODS:A literature search was con...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-020-05536-9
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:We hypothesized that a dedicated collaborative transdisciplinary Geriatric Surgery Service (GSS) will improve care for elderly colorectal surgery patients. METHODS:Patients older than 75 years of age who underwent major colorectal surgery were included in this study. The Geriatric Surgery Service employed a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1112-9
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:Restless legs syndrome (RLS) is a common and poorly understood movement disorder that leads to unpleasant leg sensations. Although RLS can be idiopathic, secondary etiologies such as iron deficiency and renal failure are common. The aim of this prospective cohort study was to evaluate whether RLS is a common...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s00268-013-2185-4
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:The specific definition of central hepatectomy (CH) (i.e., resection of segments 4-5-8 ± 1) is not uniformly used, resulting in conflicting comparisons with the more commonly performed extended hepatectomy (EH). The study aimed to compare, using propensity score matching (PSM) analysis, the incidence of post...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3584-0
更新日期：2016-11-01 00:00:00
abstract：:During laparoscopic cholecystectomy, gallbladder perforation has been reported, leading to bile leak and spillage of gallstones into the peritoneum. Because the consequences can be dangerous, conversion to laparotomy as an instant management for gallstone spillage is one of the topics of current discussion in laparosc...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7588-9
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:Laparoscopic rectal resection (LRR) for cancer is a challenging procedure, with conversion to open surgery being reported in up to 30% of cases. Since only a few studies with short follow-up have compared converted LRR and open RR (ORR), it is unclear if conversion to open surgery should be prevented by pref...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4614-x
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Primary hyperparathyroidism (HPT) is often caused by a benign parathyroid tumor, adenoma; less commonly by multiglandular parathyroid disease/hyperplasia; and rarely by parathyroid carcinoma. Patients with multiple tumors require wider exploration to avoid recurrence and have increased risk for hereditary di...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-009-0022-6
更新日期：2009-11-01 00:00:00
abstract：:Childhood papillary thyroid carcinoma is associated with more locally aggressive and more frequent distant disease than its adult counterpart. Recurrence rates tend to be higher in children, but cause-specific mortality remains low. Optimal initial treatment of childhood papillary thyroid carcinoma should include tota...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-004-7605-z
更新日期：2004-12-01 00:00:00
abstract：:The epidermal growth factor receptor family consists of four closely related transmembrane receptors: epidermal growth factor receptor (EGF-R), c-erbB-2, c-erbB-3, and c-erbB-4. Overexpression of each receptor may lead to cell transformation and contributes to tumor progression in various malignancies. Although these ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900616
更新日期：1999-10-01 00:00:00
abstract：INTRODUCTION:Unilateral adrenal hyperplasia (UAH) is a rare, surgically correctable cause of primary hyperaldosteronism (PH). We report 2 cases and review the literature for cases of PH secondary to UAH successfully treated via surgery. METHODS:Two cases of UAH treated at our institution were retrospectively reviewed....
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-0594-8
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:We analyzed perioperative platelet counts as a potential clinical marker for survival after transthoracic en bloc resection for esophageal cancer. Recent data described preoperative thrombocytosis in malignancies to be associated with poor prognosis. METHODS:A retrospective analysis from a prospective datab...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0707-x
更新日期：2010-11-01 00:00:00
abstract：BACKGROUND:The manifestations associated with non-survival after multiple trauma may vary importantly between countries and institutions. The aim of the present study was to assess the quality of performance by comparing actual mortality rates to the literature. METHODS:The study involved evaluation of a prospective c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0193-1
更新日期：2009-11-01 00:00:00
abstract：:Frequently, several multiple abdominal reexplorations are needed in patients with acute necrotizing hemorrhagic pancreatitis (ANP) or with persistent intraabdominal sepsis (PIAS). Residual undrained necrotic and septic foci lead to multiple organ failure. To provide wide-open drainage of the abdominal cavity, since 19...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658968
更新日期：1991-01-01 00:00:00
abstract：:Experience with screening for colorectal cancer has been disappointing. Prevention of this disease seems to be a more beneficial research direction. Although radical surgery presents the best treatment option, it is nonetheless an inadequate strategy by itself. A new dose intensive approach would temporally combine su...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01789207
更新日期：1991-09-01 00:00:00
abstract：:The hypervascular nature of carcinoid tumors and their metastases allows a more aggressive role by the radiologist in diagnosis and interventional management. Double-contrast gastrointestinal studies still best define the primary neoplasms. Appendiceal tumors, the most frequent site of carcinoids, frequently escape ra...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900023
更新日期：1996-02-01 00:00:00
abstract：BACKGROUND:The Acute Surgical Unit (ASU) is a recent change in management of acute general surgical patients in hospitals worldwide. In contrast to traditional management of acute surgical presentations by a rotating on-call system, ASUs are shown to deliver improved efficiency and patient outcomes. This study investig...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2497-z
更新日期：2014-08-01 00:00:00
abstract：:This study described the various components of access to care for resectable colorectal cancer, and correlated the timeliness of these components with patient satisfaction. With a prospective/retrospective cohort design, all patients undergoing surgical resection for primary colorectal cancer from 2/1/01 to 15/12/01, ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7955-1
更新日期：2005-11-01 00:00:00
abstract：BACKGROUND:Nonoperative management (NOM) of kidney gunshot injuries as an alternative to surgical exploration is rarely reported. The aim of this study was to assess the feasibility and safety of selective NOM of such injuries. METHODS:A 4-year prospective study was conducted that included all patients admitted to a L...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9888-y
更新日期：2009-03-01 00:00:00
abstract：:Thoracic and thoracoabdominal penetrating wounds are frequently encountered in urban medical centers in the United States. This study was undertaken to determine the clinical characteristics and in hospital outcome of these injuries. This was a longitudinal, nonblinded study using the established standard of care of p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF03215862
更新日期：2001-09-01 00:00:00
