Squamous metaplasia on the breast implant capsule.

Abstract:

:The development of squamous metaplasia or carcinoma is a rare occurrence in the setting of a ruptured or leaking silicone breast implant capsule. However, the oncogenic process in such a context is yet another intriguing example of how chronic inflammation plays an integral role in the tumorigenic process. Recent papers have shed light on how inflammation involving M2-tpe macrophages, lymphocytes, and other inflammatory cells at first provide the cytokines necessary to fend off an inciting foreign-body attack such as silicone from a ruptured or leaking implant. Although such a response is beneficial in keeping infection or foreign material in check, there are instances when the response may be exaggerated. It is thought that the extent and length of the response, the balance between pro-inflammatory/ anti-apoptotic and anti-inflammatory/pro-apoptotic, as well as genetic factors play important roles in determining the final result of an inflammatory insult.

journal_name

Int J Surg Pathol

authors

Alikhan MB,Nassar A,Mansoor I

doi

10.1177/1066896908329587

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

570-4

issue

6

eissn

1066-8969

issn

1940-2465

pii

1066896908329587

journal_volume

18

pub_type

杂志文章
  • Upper Gastrointestinal Langerhans Cell Histiocytosis: A Report of 2 Adult Cases and a Literature Review.

    abstract::Langerhans cell histiocytosis (LCH) with primary involvement of the upper gastrointestinal (GI) tract is rare. We report 2 adult cases of localized LCH in the upper-GI tract, including the second reported adult case of esophageal LCH and review 11 previously reported cases. Case 1 involved the esophagus of a 61-year-o...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920964566

    authors: Matsuoka Y,Iemura Y,Fujimoto M,Shibuya S,Yamada A,Fujii S,Kusaka T,Shindo T,Minamiguchi S,Haga H

    更新日期:2020-10-09 00:00:00

  • Ocular Sebaceous Carcinoma In Situ With Biphenotypic Differentiation: A Reappraisal of the Alternative Origin of the Tumor.

    abstract::Ocular sebaceous carcinoma is an uncommon, aggressive tumor arising from the Meibomian gland, Zeis gland, or sebaceous glands in the caruncle or eyelashes. We described a rare case of sebaceous carcinoma in situ in a 51-year-old female that was characterized by intraepithelial growth of sebaceous carcinoma cells with ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920917445

    authors: Yim CL,Lam SC,Yuen HKL,Cheuk W

    更新日期:2020-12-01 00:00:00

  • Syphilitic Pulmonary Inflammatory Pseudotumor: A Diagnostic Challenge.

    abstract::A 46-year-old man presented with nonproductive cough and lower limb swelling. Chest radiograph showed a left lower lobe lung mass and multiple subpleural nodules. Other investigations revealed that he had nephrotic syndrome. Core biopsies of the left lower lobe lung mass showed features of inflammatory pseudotumor wit...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920928584

    authors: Govender D,Jackson C,Chetty D

    更新日期:2021-02-01 00:00:00

  • Acute Appendicitis and Pneumatosis in a Duplicated Appendix With Schistosoma Remnants.

    abstract::Appendiceal pneumatosis is rare, reported either in the context of acute appendicitis or enterocolitis. Here, we report the case of an elderly adult in whom the acute appendicitis was associated with pneumatosis and occurred in the context of a malformed appendix with pathogenic organism remnants. A 72-year-old man pr...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915597750

    authors: Handra-Luca A,Bisseret D,Dragoescu E

    更新日期:2016-02-01 00:00:00

  • Pathologic and clinical features of Hodgkin lymphoma--like posttransplant lymphoproliferative disease.

    abstract::Because of its rarity, pathologic and clinical features of Hodgkin lymphoma-like posttransplant lymphoproliferative disorder (HL-like PTLD) are not well understood, and it is unclear whether its biological behavior is more closely related to classical Hodgkin disease or to monomorphic B-cell PTLD. The authors compared...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896909338597

    authors: Krishnamurthy S,Hassan A,Frater JL,Paessler ME,Kreisel FH

    更新日期:2010-08-01 00:00:00

  • Giardia Is Often Overlooked on Histopathologic Examination: A High-Volume, Single-Institution Experience.

    abstract:AIMS. GIARDIA:is sometimes missed by the pathologist, and we sought to determine how often this occurs at our institution-a large tertiary care center with a subspecialty gastrointestinal pathology service and what certain clinical and histologic clues can be used to flag cases with a higher likelihood of infection, ta...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920947795

    authors: Shen MJ,Voltaggio L,Robertson S

    更新日期:2020-08-10 00:00:00

  • PAX--FKHR fusion genes and AChR-gamma in Chinese patients with rhabdomyosarcoma: diagnosis using formalin-fixed archival tissues.

    abstract::The majority of alveolar RMSs have t(2;13)(q35;q14) or (1:13)(p36;q14),which generate PAX3/7 -FKHR fusion genes. Here, the authors detected the PAX3/7-FKHR fusion transcripts in 17 formalin-fixed, paraffin-embedded RMSs and 26 other SRCTs using one-step RT-PCR. PAX3 -FKHR and PAX7-FKHR transcripts were positive in 4/8...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896908323922

    authors: Chang B,Pang LJ,Qi Y,Liu CX,Cao Y,Li HA,Hu WH,Jiang JF,Zhang WJ,Li F

    更新日期:2009-02-01 00:00:00

  • Well-differentiated chondrosarcoma of the humerus with prominent granular cell component: a hitherto unreported occurrence.

    abstract::We report the case of a well-differentiated chondrosarcoma of the proximal humerus in a 60-year-old man that featured a prominent component of granular cells, the granules being shown by electron microscopy to be lysosomal. Although secondary granular cell changes have been described in a large variety of tumor types,...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/106689690601400211

    authors: Cremonini A,Kuhn E,De Biase P,Franchi A

    更新日期:2006-04-01 00:00:00

  • Superficial CD34-Positive Fibroblastic Tumor.

    abstract::Superficial CD34-positive fibroblastic tumor (SCPFT) is a recently described entity that, despite significant pleomorphism, carries a good prognosis. We briefly describe this tumor and its principal differential diagnoses. Recognition of SCPFTs, including the clinical context in which they arise, is important to avoid...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920938133

    authors: Foot O,Hallin M,Bagué S,Jones RL,Thway K

    更新日期:2020-12-01 00:00:00

  • Immunohistochemical analysis of expressions of RB1, CDK4, HSP90, cPLA2G4A, and CHMP2B is helpful in distinction between myxofibrosarcoma and myxoid liposarcoma.

    abstract::The role and diagnostic efficacy of gene and protein products RB1, CDK4, CHMP2B, HSP90, and cPLA2G4A, all previously shown to be involved in tumor genesis and cell proliferation, were examined by immunohistochemical techniques in 32 cases of myxofibrosarcomas and 29 myxoid liposarcomas (all diagnosis had been confirme...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896914532539

    authors: Wang T,Goodman MA,McGough RL,Weiss KR,Rao UN

    更新日期:2014-10-01 00:00:00

  • Clinicopathologic Features of Benign Neurogenic Tumor of Urinary Bladder.

    abstract:BACKGROUND:Benign neurogenic tumor involving the urinary bladder is a very rare and heterogeneous disease group. The clinical and radiological diagnosis may be difficult because of the disease's rarity and the histological similarities of each disease especially in needle biopsy specimens. However, accurate diagnosis i...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896917742722

    authors: Lee C,Kim B,Song B,Park JH,Moon KC

    更新日期:2018-05-01 00:00:00

  • Testicular juvenile granulosa cell tumor in a newborn: case report and review of the literature.

    abstract::Juvenile granulosa cell tumor of the testis of neonates and infants is an uncommon lesion frequently associated with abnormal sex chromosome and ambiguous genitalia. This report describes a juvenile granulosa cell tumor arising in the testis of a neonate. Chromosome analysis of the tumor showed a normal male karyotype...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896907302423

    authors: Alexiev BA,Alaish SM,Sun CC

    更新日期:2007-07-01 00:00:00

  • Pigmented Ependymoma of the Fourth Ventricle-A Curious Entity: Report of a Rare Case With Review of Literature.

    abstract::A 16-year-old boy presented with a tumor located in fourth ventricle, which showed histological features of an ependymoma replete with perivascular pseudorosettes and true ependymal rosettes. Interestingly, many of the tumor cells exhibited abundant cytoplasm stuffed with a grayish brown pigment. Histochemical stains ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920926700

    authors: Malhotra A,Rao S,Santhoshkumar R,Muralidharan N,Mitra S,Shetty S

    更新日期:2021-02-01 00:00:00

  • Histopathological changes in the gastrointestinal tract due to medications: an update for the surgical pathologist (part II of II).

    abstract::In keeping with the stated goal of providing the surgical pathologist with tools to recognize abnormalities of the gastrointestinal (GI) tract due to drugs (AGIDS), in part II of this review we embark in a more organ-based description of AGIDS. Adequate space is given to the numerous adverse gastrointestinal effects o...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896913502230

    authors: De Petris G,Caldero SG,Chen L,Xiao SY,Dhungel BM,Spizcka AJ,Lam-Himlin D

    更新日期:2014-05-01 00:00:00

  • Autoimmune-Like Hepatitis: A "Hepatitic" Manifestation of Chronic Graft Versus Host Disease in Post-Stem Cell Transplant.

    abstract::A 59-year-old female received a matched related donor stem cell transplant for chronic myelogenous leukemia. After being successfully treated with prednisone for chronic graft versus host disease that initially started 50 days posttransplant, she developed hepatic dysfunction during the steroid taper on day 531, as ev...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915610817

    authors: Baniak NM,Kanthan R

    更新日期:2016-04-01 00:00:00

  • Diaphragm disease of the small intestine: an interesting case report.

    abstract::Diaphragm disease of small intestine usually presents with nonspecific clinical features. Radiological investigations often fail to differentiate it from small intestinal tumors and inflammatory bowel disease. It is therefore diagnosed on final histology after surgical resection. We hereby report an interesting case o...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896914563392

    authors: Ullah S,Ajab S,Rao R,Raghunathan G,DaCosta P

    更新日期:2015-06-01 00:00:00

  • Proximal-Type Epithelioid Sarcoma: Report of an Unusual Case in the Uterine Cervix.

    abstract::Epithelioid sarcoma is a rare malignant mesenchymal neoplasm (less than 1% of all sarcomas) with epithelioid morphology. Among the 2 subtypes, proximal represents only one-third of cases and commonly involves deep tissues of pelvic region, including the perineum, genital area, and groin, and occurs more frequently in ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896917696744

    authors: Suárez-Zamora DA,Barrera-Herrera LE,Rodríguez-Urrego PA,Palau-Lázaro MA

    更新日期:2017-08-01 00:00:00

  • Glomus tumor of the duodenum: a case report.

    abstract::We describe a rare case of glomus tumor of the duodenum. The tumor was detected in a 46-year-old man being investigated for episodes of gastrointestinal bleeding. The excised specimen showed a 2.3 x 1.5 x 1.5 cm gray-tan tumor involving the mucosa and the submucosa. The overlying mucosa was focally ulcerated. Histolog...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/106689690401200417

    authors: Jundi M,Lack EE,Brun EA,Esquivel J,Kumar D

    更新日期:2004-10-01 00:00:00

  • Lymphoplasmacyte-Rich Meningioma With Atypical Angiomatous Feature and an Increased Deposition of IgG4-Positive Plasma Cells: An Unusual Case Report.

    abstract::Lymphoplasmacyte-rich meningioma (LPRM) is an extremely rare variant of meningioma, and a small percentage of LPRM may be associated with IgG4-related disease. To date, the coexistence of 2 rare meningioma variants consisting of LPRM and angiomatous meningioma within one neoplasm has not been reported in the literatur...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896917728103

    authors: Son HJ,Yu IK,Kim SM

    更新日期:2018-02-01 00:00:00

  • A Novel Case of Mammary-Type Myofibroblastoma With Sarcomatous Features.

    abstract::Mammary-type myofibroblastoma (MFB) is a benign spindle cell tumor of the breast and soft tissue characterized by 13q14 alterations leading to loss of Rb-1 protein expression, a feature shared among spindle cell lipoma and cellular angiofibroma. In this article, we present a novel case of MFB arising in the left breas...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896920947465

    authors: Strait AM,Linos K,Tafe LJ,Muller KE

    更新日期:2020-08-05 00:00:00

  • Borderline serous cystadenocarcinoma with coexistent angiosarcoma: an unusual form of ovarian carcinosarcoma.

    abstract::A 45-year-old woman presented with a short history of abdominal distension and features of intestinal obstruction. Computed tomography examination of the abdomen revealed a solid and cystic mass in the region of the left ovary, but spread within the abdomen was also noted. The ovarian tumor was removed, and an omentec...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/106689690100900411

    authors: Pillay K,Essa AS,Chetty R

    更新日期:2001-10-01 00:00:00

  • Lymph node infarction associated with infectious mononucleosis: report of a case resembling lymph node infarction associated with malignant lymphoma.

    abstract::A completely infarcted lymph node should alert the pathologist to the high possibility of malignant lymphoma. The lymph node lesion of infectious mononucleosis (IM) shows marked histologic diversity and occasionally may be confused with malignant lymphoma. We report a rare case of IM showing extensive lymph node infar...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/106689690201000312

    authors: Kojima M,Nakamura S,Sugihara S,Sakata N,Masawa N

    更新日期:2002-07-01 00:00:00

  • Peritoneal bile granulomas identified at Cesarean section and mimicking disseminated malignancy.

    abstract::A 37-year-old woman was found to have multiple peritoneal nodules, including on the uterine serosa, at Cesarean section. Histology showed yellow crystalline material surrounded by histiocytes and occasional multinucleate giant cells. Further enquiry revealed that the patient underwent a cholecystectomy for a perforate...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896911409930

    authors: McVeigh G,McComiskey M,McCluggage WG

    更新日期:2012-02-01 00:00:00

  • Uterine glomeruloid hemangioma in a patient without POEMS syndrome.

    abstract::Cutaneous glomeruloid hemangioma is a hallmark of POEMS syndrome. These patients have elevated serum levels of vascular endothelial growth factor. The authors report an extracutaneous uterine glomeruloid hemangioma in an 82-year-old woman with a history of breast and endometrial carcinomas. Within the lumen of myometr...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896911429297

    authors: Giner F,Compañ A,Monteagudo C

    更新日期:2012-08-01 00:00:00

  • Mucosal Schwann Cell Hamartoma of the Rectosigmoid Junction: A Rare Lesion Mimicking Mucosal Prolapse Syndrome and Other Neural Lesions.

    abstract::In this article, we report the case of a 40-year-old woman with a sessile polyp of the rectosigmoid junction that underwent endoscopic resection. The resected specimen showed spindle cell proliferation with eosinophilic cytoplasm between mucosal crypts, mimicking mucosal prolapse syndrome. However, these were immunohi...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896918818897

    authors: Hashimoto H,Usui G,Sakai E,Ohata K,Morikawa T

    更新日期:2019-08-01 00:00:00

  • Sinonasal SMARCB1 (INI1) Deficient Carcinoma With Yolk Sac Tumor Differentiation: Report of a Case and Comparison With INI1 Expression in Gonadal Germ Cell Tumors.

    abstract::SMARCB1 (INI1) deficient sinonasal carcinoma is a recently recognized entity with wide histomorphologic spectrum. We present a case of this carcinoma that contained, in addition to a "common" morphology, scattered foci of yolk sac tumor differentiation. The tumor occurred in paranasal sinuses in a 44-year-old woman. I...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896917741549

    authors: Zamecnik M,Rychnovsky J,Syrovatka J

    更新日期:2018-05-01 00:00:00

  • α-Fetoprotein-Producing Hepatoid Gastric Adenocarcinoma With Osteoclast-Like Giant Cells and Neuroendocrine Differentiation: A Case Study With Molecular Profiling.

    abstract::Here we present the case of a 73-year-old woman with an ulcerated, advanced, hepatoid, and α-fetoprotein-producing poorly differentiated (G3) primary gastric adenocarcinoma pT3 N3a M1 with multinucleated cells and evident neuroendocrine component. This tumor was consistent with giant cell tumor type gastric carcinoma ...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896915586807

    authors: Wincewicz A,Kowalik A,Zięba S,Lewitowicz P,Góźdź S,Sulkowski S

    更新日期:2015-10-01 00:00:00

  • MUM-1 expression differentiates tumors in the PEComa family from clear cell sarcoma and melanoma.

    abstract::PEComas are mesenchymal neoplasms composed of perivascular epithelioid cells (PEC) and include a spectrum of tumors. PEComas and malignant melanoma share common morphological, immunohistochemical, and ultrastructural features, such as epithelioid cell morphology and melanocytic immunophenotype. Melanocytic markers com...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896911418204

    authors: Ferenczi K,Lastra RR,Farkas T,Elenitsas R,Xu X,Roberts S,Brooks JS,Zhang PJ

    更新日期:2012-02-01 00:00:00

  • Topography of Protein Kinase C βII in Benign and Malignant Melanocytic Lesions.

    abstract:BACKGROUND:Protein kinase C βII promotes melanogenesis and affects proliferation of melanocytic cells but is frequently absent or decreased in melanoma cells in vitro. OBJECTIVE:To investigate PKC-βII expression and spatial distribution within a lesion in various benign and malignant melanocytic proliferations. METHO...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章

    doi:10.1177/1066896917706026

    authors: Krasagakis K,Tsentelierou E,Chlouverakis G,Stathopoulos EN

    更新日期:2017-09-01 00:00:00

  • Presentation of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma in a Warthin Tumor: Case Report and Literature Review.

    abstract::Warthin tumor is the second most common salivary gland neoplasm. It occurs more commonly in males than in females. Malignant transformation in Warthin tumor is a rare but well-recognized phenomenon; however, the development or presentation of lymphoma in a Warthin tumor is rare. An 80-year-old man presented with painl...

    journal_title:International journal of surgical pathology

    pub_type: 杂志文章,评审

    doi:10.1177/1066896917734371

    authors: Jawad H,McCarthy P,O'Leary G,Heffron CC

    更新日期:2018-05-01 00:00:00