Sustainability of a well-monitored salt iodization program in Iran: marked reduction in goiter prevalence and eventual normalization of urinary iodine concentrations without alteration in iodine content of salt.

abstract：OBJECTIVE:In the mountainous areas of Azerbaijan the schoolchildren suffer from severe Iodine Deficiency (ID) with median Urinary iodine excretion (UIE) 36 mcg/l and prevalence of goiter 99% (estimated by US). In a population of 293,000 schoolchildren aged 8-14 y.o. we administered capsules containing 190 mg of iodized...

journal_title：Journal of endocrinological investigation

authors： Markou KB,Georgopoulos NA,Makri M,Vlasopoulou B,Anastasiou E,Vagenakis GA,Kouloubi K,Theodosopoulos N,Lazarou N,Veizis A,Sakellaropoulos G,Vagenakis AG

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:The aim of the study was to evaluate diurnal blood pressure (BP) profiles in patients with primary aldosteronism and to compare them to those in subjects with essential hypertension. The effects of specific therapy on the circadian BP profiles have been studied. MATERIALS AND METHODS:Sixty-four patients wit...

journal_title：Journal of endocrinological investigation

authors： Zacharieva S,Orbetzova M,Elenkova A,Stoynev A,Yaneva M,Schigarminova R,Kalinov K,Nachev E

更新日期：2006-01-01 00:00:00

abstract：:Metabolic diseases are associated with chronic low-grade inflammation, which has been indicated as a potential mediator of endothelial dysfunction and cardiovascular disease. Visceral adiposity is thought to be the starting condition of the inflammatory state through the release of inflammatory cytokines, including TN...

journal_title：Journal of endocrinological investigation

authors： Maiorino MI,Bellastella G,Giugliano D,Esposito K

更新日期：2018-11-01 00:00:00

abstract：:Excess production of proopiomelanocortin (POMC)-derived peptides with aldosterone-stimulating activity has been suggested to play a pathogenetic role in idiopathic hyperaldosteronism (IHA). To further investigate this issue, the opiate receptor antagonist naloxone was administered to 14 patients with primary aldostero...

journal_title：Journal of endocrinological investigation

authors： Fallo F,Boscaro M,Sonino N,Mantero F

更新日期：1988-04-01 00:00:00

abstract：:Pyoderma gangrenosum is a rare chronic and recurrent skin disease characterized by progressing lesions from papulopustules to large necrotic sterile ulcers. Its definite etiology remains unknown. In a 40-year-old woman with typical pyoderma gangrenosum an intrasellar mass with suprasellar extension was diagnosed and r...

journal_title：Journal of endocrinological investigation

authors： Chanson P,Timsit J,Kujas M,Violante A,Guillausseau PJ,Derome PJ,Warnet A,Lubetzki J

更新日期：1990-09-01 00:00:00

abstract：:Evaluation of thyroid status by measurement of free thyroid hormone concentrations seems particularly helpful in conditions with altered serum binding proteins. In pregnancy, a condition of increased thyroxine binding globulin, serum free thyroxine (FT4) and free triiodothyronine (FT3) concentrations have been reporte...

journal_title：Journal of endocrinological investigation

authors： Roti E,Gardini E,Minelli R,Bianconi L,Flisi M

更新日期：1991-01-01 00:00:00

abstract：:We treated a 10 6/12 year old prepubertal male with hypophosphatemic rickets, who was growing poorly despite appropriate treatment with calcitriol and phosphate, with exogenous growth hormone (for an initial trial period of 4 months, followed by 14 months of continuous treatment at a dose of 4 IU three times weekly) e...

journal_title：Journal of endocrinological investigation

authors： Lanes R,Harrison HE

更新日期：1990-11-01 00:00:00

abstract：:The effect of right- and left-sided intra-amygdaloid injection of kainic acid on the hypothalamo-hypophyseal-testicular axis was studied in rats. Both right- and left-sided injection of the neurotoxin into the amygdala resulted in a significant decrease in basal testosterone secretion in vitro of both testes and in se...

journal_title：Journal of endocrinological investigation

authors： Banczerowski P,Csaba Z,Csernus V,Gerendai I

更新日期：2003-05-01 00:00:00

abstract：:We describe a patient with Cushing's syndrome and metastatic small cell lung cancer. The plasma ACTH concentrations were markedly elevated (91.6 pmol/L), and the AM cortisol did not suppress by > 50% overnight after administration of 8 mg dexamethasone, both consistent with the ectopic ACTH syndrome. Immunohistochemic...

journal_title：Journal of endocrinological investigation

authors： Auchus RJ,Mastorakos G,Friedman TC,Chrousos GP

更新日期：1994-06-01 00:00:00

abstract：:Thyrotropin-releasing hormone (TRH)-like material was found in human retina obtained at autopsy from eyes used for corneal grafts. The TRH-like material was extracted with methanol and was found to be indistinguishable from synthetic TRH in its immunoreactivity and bioreactivity and in its proteolytic degradation by f...

journal_title：Journal of endocrinological investigation

authors： Martino E,Nardi M,Vaudagna G,Simonetti S,Cilotti A,Pinchera A,Venturi G,Seo H,Baschieri L

更新日期：1980-07-01 00:00:00

abstract：:Papillary thyroid cancer (PTC) accounts for 80% of all thyroid malignancies, and genetic alterations associated to its etiology remain largely unknown. Chromosomal band 11q13 seems to be one of the most frequently amplified regions in human cancer, providing several candidate genes that need detailed characterization....

journal_title：Journal of endocrinological investigation

authors： Hidalgo M,Saez ME,Martinez-Tello FJ,Moron FJ,Ferrero-Herrero E,Labalde-Martinez M,Rigopoulou D,Ballestin-Carcavilla C,Ruiz A,Royo JL,Ramirez-Lorca R

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Glucagon-like peptide-1 (GLP-1) and its potent analog, exendin-4, are well known to inhibit β- cell apoptosis and promote β-cell proliferation. Meanwhile, cytokines, such as interleukin-1β (IL-1β), stimulate inducible nitric oxide synthase (iNOS) expression and nitric oxide overproduction leading to β-cell d...

journal_title：Journal of endocrinological investigation

authors： Liu XH,Wang YP,Wang LX,Chen Z,Liu XY,Liu LB

更新日期：2013-11-01 00:00:00

abstract：:Prolactin (PRL) circulates as multiple molecular weight variants: glycosylated phosphorylated, deamidated and sulphated forms. The profiles of the forms, as determined by isoelectrofocusing (IEF), differ in physiological and pathological conditions. The case of a 72-year-old woman affected by an invasive prolactinoma ...

journal_title：Journal of endocrinological investigation

authors： Guido R,Valenti S,Foppiani L,De Martini D,Cossu M,Giusti M

更新日期：1997-05-01 00:00:00

abstract：:The aim of the study was to examine the effects of strenuous training on the hypothalamic- pituitary-adrenal axis activity. Exercise tests and saliva collections for analysis of awakening cortisol response (ACR) and midnight cortisol were performed before and after a 7-day period of intensified training in a group of ...

journal_title：Journal of endocrinological investigation

authors： Minetto MA,Lanfranco F,Tibaudi A,Baldi M,Termine A,Ghigo E

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Increasing evidence showed that telomere length was shorter in age-related diseases, but the mechanism of this phenomenon is still unclear. AIM:To determine whether telomere shortening occurs in Type 1 diabetes (T1D) and Type 2 diabetes (T2D), and explore the effect of antioxidant status on the telomere len...

journal_title：Journal of endocrinological investigation

authors： Ma D,Zhu W,Hu S,Yu X,Yang Y

更新日期：2013-12-01 00:00:00

abstract：:No head-to-head comparisons are available to analyze the efficacy of octreotide (LAR) and lanreotide (LAN) as first-line treatment of acromegaly.We compared the efficacy of these two drugs in 54 newly diagnosed patients (21 women, 33 men), 27 treated with LAR (10-30 mg every 28 days) and 27 with LAN (60-90 mg/28 days)...

journal_title：Journal of endocrinological investigation

authors： Auriemma RS,Pivonello R,Galdiero M,De Martino MC,De Leo M,Vitale G,Lombardi G,Colao A

更新日期：2008-11-01 00:00:00

abstract：:We evaluated the 24-h profile of serum melatonin (MT) in 16 patients with Cushing's syndrome (11 pituitary- and 5 adrenal-dependent) aged 38.1 +/- 13.8 years and in 19 patients with acromegaly due to GH-secreting pituitary adenoma aged 52 +/- 11.9 years. Thirty-three healthy subjects aged 30 +/- 7 years and 26 healthy...

journal_title：Journal of endocrinological investigation

authors： Terzolo M,Piovesan A,Alì A,Codegone A,Pia A,Reimondo G,Torta M,Paccotti P,Borretta G,Angeli A

更新日期：1995-01-01 00:00:00

abstract：:A 52-year-old male presented himself with tachycardia crises which appeared first during childhood, increased in frequency without goiter or exophthalmos. Cardiac and adrenergic diseases were excluded. The thyroid function was normal regarding T4, free T4 and T3, TBG, radioiodine uptake, TSH and T3 suppressibility; ho...

journal_title：Journal of endocrinological investigation

authors： Jaffiol C,Baldet L,Torresani J,Bismuth J,Papachristou C

更新日期：1990-11-01 00:00:00

abstract：:During a systematic study of women with idiopathic galactorrhea, we observed several patients with normal random serum prolactin (PRL) levels and normal menses, but abnormal sellar tomograms characteristic of a pituitary adenoma. To test the hypothesis that these women might have intermittent PRL hypersecretion, we st...

journal_title：Journal of endocrinological investigation

authors： Kapcala LP,Molitch ME,Arno J,King LW,Reichlin S,Wolpert SM

更新日期：1984-10-01 00:00:00

abstract：PURPOSE:Although a nation-wide salt iodization program on voluntary basis was implemented in 2005, many areas in our country are still characterized by mild iodine deficiency. Differently from the rest of Italy, an efficient program of iodine prophylaxis was implemented in 1981 in the Autonomous Province of Bolzano. Th...

journal_title：Journal of endocrinological investigation

authors： Olivieri A,Radetti G,Medda E,Italian Study Group for Congenital Hypothyroidism.

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:Growth hormone deficiency (GHD) is the most common endocrine late effect observed in childhood cancer survivors (CCS) previously submitted to cranial irradiation. Radiation therapy can also increase the risk of second neoplasms (SNs). Since in previous studies GH replacement therapy was associated with increase...

journal_title：Journal of endocrinological investigation

authors： Brignardello E,Felicetti F,Castiglione A,Fortunati N,Matarazzo P,Biasin E,Sacerdote C,Ricardi U,Fagioli F,Corrias A,Arvat E

更新日期：2015-02-01 00:00:00

abstract：:This study was performed to evaluate the antihypercalciuric effect of calcitonin (CT), a potent inhibitor of bone osteoclastic activity, on idiopathic hypercalciuria (IH). Forty-two stone formers were studied: 18 suffered from fasting hypercalciuria (FH), 12 from nonfasting hypercalciuria (NFH) and 12 were normocalciu...

journal_title：Journal of endocrinological investigation

authors： Filipponi P,Mannarelli C,Gubbiotti G,Blass A,Moretti I,Tini S,Giuseppetti N,Ballanti S,Morucci P

更新日期：1988-07-01 00:00:00

abstract：: ...

journal_title：Journal of endocrinological investigation

authors： Lazzeri D,Al-Mousawi A,Nicoli F

更新日期：2018-12-01 00:00:00

abstract：:Obesity and insulin resistance are common features of Type 2 Diabetes. A new protein called resistin has been shown to be secreted by adipocytes in mice and to influence insulin sensitivity. The goal of the present study was to investigate the associations between one polymorphism (g-420C>G) of the human resistin gene...

journal_title：Journal of endocrinological investigation

authors： Bouchard L,Weisnagel SJ,Engert JC,Hudson TJ,Bouchard C,Vohl MC,Pérusse L

更新日期：2004-12-01 00:00:00

abstract：:Unfortunately, the author name and his affiliation were published in the original publication. They have now been removed. ...

journal_title：Journal of endocrinological investigation

authors：

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:Graves' orbitopathy (GO) is an inflammatory orbital disease of autoimmune origin with the potential to cause severe functional and psychosocial effects. The pathogenesis has not been fully elucidated. We investigated whether DNA methylation was associated with GO incidence in Chinese patients. MATERIALS AND ...

journal_title：Journal of endocrinological investigation

authors： Xin Z,Hua L,Shi TT,Tuo X,Yang FY,Li Y,Cao X,Yang JK

更新日期：2018-06-01 00:00:00

abstract：:To assess the role of the renin-angiotensin system in the control of aldosterone reease in response to heat exposure, 6 sodium restricted subjects were studied on three random experimental days: a control day and two heat exposure days (46C, 35 mbar, 90 min) with and without propranolol. Plasma aldosterone, renin acti...

journal_title：Journal of endocrinological investigation

authors： Brandenberger G,Follenius M,Oyono S

更新日期：1980-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the hypothesis that interleukin-1beta (IL-1beta) might be involved in the increase of the circulating levels of placental-derived CRH leading to the initiation of pre-term labor. SUBJECTS AND METHODS:Forty-eight primigravidae with a singleton viable pregnancy between ...

journal_title：Journal of endocrinological investigation

authors： Vitoratos N,Mastorakos G,Kountouris A,Papadias K,Creatsas G

更新日期：2007-01-01 00:00:00

abstract：:Glucocorticoid-induced osteoporosis (GIO) is the most common form of secondary osteoporosis. GC influence bone metabolism via a modulation of different components of the GH/IGF-I system. GH has multiple anabolic effects on bone, either direct or mediated by IGF-I. GH-deficient subjects have significant reduction in bo...

journal_title：Journal of endocrinological investigation

authors： Lombardi G,Colarusso S,Di Somma C,Guerra E,Tauchmanova L,Colao A

更新日期：2008-07-01 00:00:00

abstract：:We herein describe a 40-year-old woman with hyperprolactinemia, an empty sella and two extrasellar intracranial recurrent tumors which were revealed 23 years after the first transfrontal craniotomy and 18 years after the second transfrontal surgery and irradiation to a provable prolactin-producing pituitary macroadeno...

journal_title：Journal of endocrinological investigation

authors： Fujikawa M,Okamura K,Sato K,Shiratsuchi M,Yao T,Mizokami T,Fujishima M

更新日期：2001-06-01 00:00:00