Abstract:
:Intravenous supra-pharmacological doses of corticosteroids are used in various inflammatory and autoimmune conditions because they are cumulatively less toxic than sustained steroid treatment at lower quantitative dosage. Their action is supposed to be mediated through non-genomic actions within the cell. Common indications for use in children include steroid resistant and steroid dependent nephrotic syndrome, rapidly progressive glomerulonephritis, systemic vasculitis, systemic lupus erythematosus, acute renal allograft rejection, juvenile rheumatoid arthritis, juvenile dermatomyositis, pemphigus, optic neuritis, multiple sclerosis and acute disseminated encephalomyelitis. Methylprednisolone and dexamethasone show similar efficacy in most conditions. Therapy is associated with significant side effects including worsening of hypertension, infections, dyselectrolytemia and behavioral effects. Adequate monitoring is essential during usage.
journal_name
Indian J Pediatrjournal_title
Indian journal of pediatricsauthors
Sinha A,Bagga Adoi
10.1007/s12098-008-0210-7subject
Has Abstractpub_date
2008-10-01 00:00:00pages
1057-66issue
10eissn
0019-5456issn
0973-7693journal_volume
75pub_type
杂志文章abstract::Computed tomography (CT) is an indispensable tool for imaging of the thorax and there is virtually no alternative without associated radiation burden. The authors demonstrate ultra-low-dose CT of the thorax in three interesting cases. In an 18-y-old girl with rheumatoid arthritis, CT of the thorax identified alveoliti...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-016-2175-2
更新日期:2016-11-01 00:00:00
abstract::In patients with Mycoplasma pneumonia extrapulmonary manifestations such as encephalitis, meningitis, cerebellar and brain stem involvement, cranial nerve lesions, peripheral neuropathy, polymyositis have been observed. We report a 16-year-old girl with M. pneumonia infection, acute behavioral changes and coma. Treatm...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02859473
更新日期:2000-06-01 00:00:00
abstract::The authors report a case of 13-y-old boy who presented with pain in bilateral knee and ankle joints accompanied by petechiae all over the body and hematochezia. On investigation, he had pancytopenia, which on subsequent evaluation revealed aplastic anemia. On investigation for short stature, he was diagnosed as a cas...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-011-0579-6
更新日期:2012-10-01 00:00:00
abstract::Frank-Ter Haar syndrome is an unusual type of skeletal dysplasia with megalocornea and developmental delay. It is usually transmitted as autosomal recessive disorder. Only a few cases have been reported in the literature and none from India. The authors report a case with other unusual features and a short review of t...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-011-0599-2
更新日期:2012-08-01 00:00:00
abstract::A two-and-a-half-year-old male child presented with recurrent attacks of intractable vomiting, psychomotor retardation since 14 months of age. He had also lower cranial nerve palsy and corticospinal involvement. Magnetic resonance imaging had shown multiple well circumscribed areas of hypointusity in T1 weighted image...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02730822
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVE:The present study aimed at assessing the population prevalence of goiter and iodine deficiency in school children of 6-12 yr living in urban slums of Bhubaneswer, the capital city of Orissa. METHODS:A cross-sectional study was performed using the 30-cluster sampling methodology and surveillance methods for i...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-007-0169-9
更新日期:2007-10-01 00:00:00
abstract::Nutritional support to patients in neonatal and pediatric intensive care units is critical not only to minimize negative nitrogen balance but also to promote growth and development. Continuous technological and logistical advances in the Western countries have improved the efficacy and reduced the complications of par...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To identify the causes and contributing factors of persistent pneumonia in children. METHODS:41 cases with persistent pneumonia were investigated (biochemical, microbiological, histopathological, immunological and radiological tests) to find out the underlying cause. RESULTS:Out of 41 cases, 8 had pulmonary...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0272-1
更新日期:2009-12-01 00:00:00
abstract::The reasons for comparatively low infant mortality rates in the Indian state of Kerala are examined. The importance of improvements in education and in the health care delivery system is stressed. ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02751009
更新日期:1985-09-01 00:00:00
abstract::Bone marrow transplantations have a definite role in treatment of leukemias and lymphomas. In acute myeloid leukemia and CML an allogeneic transplant using an HLA identical donor certainly provides a far superior survival than chemotherapy. Patients with Ph' chromosome need to be transplanted in first remission if a s...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/BF02751432
更新日期:1993-07-01 00:00:00
abstract::Assay of hexosaminidase A and B enzymes in four cases with developmental regression and cherry red spot on fundus examination confirmed that three cases had Tay-Sachs disease, and one case had Sandhoff disease. Prenatal diagnosis was carried out by hexosaminidase enzyme assay in amniotic fluid and cells in one family,...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02755072
更新日期:1995-07-01 00:00:00
abstract:OBJECTIVE:To compare cultures throat swab after physiotherapy with results of sputum culture in identification of lower airway pathogens in children with cystic fibrosis. METHODS:387 samples of sputum cough swabs, throat swab and throat swab after physiotherapy were collected from 48 patients of cystic fibrosis and cu...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02725650
更新日期:2004-01-01 00:00:00
abstract::Hirschsprung disease is a common cause of neonatal and infantile large gut obstruction. It is characterised by varying extent of contiguous aganglionosis extending from the anorectum proximally. Since its recognition, the diagnosis and management has continuously evolved with advances in histological evaluation and su...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s12098-017-2371-8
更新日期:2017-08-01 00:00:00
abstract::Major areas in which innovative approaches in medical education have been tried include student selection, learning strategies, and community orientation. It is relatively easier to implement innovations in a new institution. In established medical schools, running two simultaneous curricula tracks, the traditional an...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02751045
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVES:To compare early child care practices at home as possible risk factors among children between 2 and 6 y of age with autism and a control group of normal children without any symptom of autism, presenting at the well-baby/immunization clinic. METHODS:This case control study was undertaken at the autism clini...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1602-5
更新日期:2014-12-01 00:00:00
abstract::We present a male infant with hydrocephalus, cleft lip/palate, micrognathia, club foot, laryngeal stenosis and ostium secundum type atrial septal defect. The karyotype was 46 XY. The combination of malformations observed overlaps with the characteristic findings of hydrolethalus syndrome, Meckel syndrome, Smith-Lemli-...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02898455
更新日期:2006-08-01 00:00:00
abstract::This article aims to describe the National Family Health Survey (NFHS) being carried out in India with its first round during 1992-93 (NFHS-I) and second round during 1998-99 (NFHS-II), with special reference to information available in relation to children. The survey was on lines of the existing systems of Demograph...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02722355
更新日期:2001-11-01 00:00:00
abstract:OBJECTIVE:To assess the trends and outcomes in referrals of 'phimosis for circumcision' to a tertiary care pediatric surgical department. METHODS:This is a prospective study of 100 consecutive children of presumed phimosis referred for circumcision. They were assessed and classified by the senior author as having eith...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-009-0120-3
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of peripheral neuropathy in HIV infected children (>5 y) receiving stavudine-based combination anti-retroviral treatment (ART) for more than 3 mo in a cross-sectional study. METHODS:History, detailed neurological examination and nerve conduction studies were performed. RESULTS:Forty...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-014-1477-5
更新日期:2015-02-01 00:00:00
abstract:: ...
journal_title:Indian journal of pediatrics
pub_type: 信件
doi:10.1007/s12098-018-2702-4
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the epidemiology of rotavirus gastroenteritis in Haryana post-introduction of rotavirus vaccine. Expanded National rotavirus surveillance network in India reported high burden of rotavirus diarrhea in India. The Government of India introduced the monovalent rotavirus vaccine made in India by Bhara...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-020-03614-3
更新日期:2021-01-14 00:00:00
abstract:OBJECTIVE:To determine the prooxidant-antioxidant balance (PAB) in neonatal asphyxia and compare it with values for PAB in healthy neonates. METHODS:In a prospective observational study, serum PAB of umbilical cord blood of 30 neonates with asphyxia [pH < 7.2, low Apgar score, signs of respiratory distress syndrome (R...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-013-1239-9
更新日期:2014-03-01 00:00:00
abstract:OBJECTIVES:To generate consensus on the assessment of hypotonia in the pediatric population, more specifically with respect to the clinical characteristics and first line tests and methods to be used to assess these characteristics. METHODS:Consensus methodology was used. A sample of experts was recruited based on spe...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-013-1018-7
更新日期:2013-08-01 00:00:00
abstract::Hypophosphatemic rickets (HR) has generated a lot of interest in recent times. There is need to recognize this disorder and differentiate it from the more common nutritional rickets because the therapy is different. It is also important to emphasize that a detailed clinical examination with pedigree analysis and easil...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723852
更新日期:1999-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the effect of folic acid supplementation on seizure control in folate deficient children receiving long term antiepileptic therapy. METHODS:In a prospective interventional study, 140 children between age group 6 mo to 180 mo fulfilling the inclusion criteria were enrolled in study group, from Oct...
journal_title:Indian journal of pediatrics
pub_type: 临床试验,杂志文章
doi:10.1007/s12098-018-2608-1
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVES:To compare parent reported sleep behaviors of children with Autism Spectrum Disorders (ASD) and normal healthy controls and to examine the association of sleep disturbances with daytime behavioral difficulties in children with ASD. METHODS:Sixty ASD children (85% boys) (Mean age=6.1 y, SD=2.4) were recruite...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s12098-018-2731-z
更新日期:2019-01-01 00:00:00
abstract::To study pulmonary function tests (PFT) in multiple transfusion recipient thalassemics, PFTs were done for 30 thalassemics and 20 matched controls. Confirmed cases of thalassemia on regular transfusion therapy were the subject of study. Apart from history and physical examination of the thalassemics, serum ferritin es...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02723198
更新日期:2001-03-01 00:00:00
abstract::The authors present a case of a preterm newborn with congenital infection of herpes simplex virus type 2. The patient was treated with newly recommended high intravenous doses of acyclovir. It can be supposed that it reduces mortality, but the high morbidity continues to be a problem. ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract::Essential fatty acids cannot be synthesized in the body but they are required for maintenance of optimal health. There are two classes of polyunsaturated fatty acids (PUFAs)--omega-6 and omega-3. The parent omega-6 fatty acid, linoleic acid (LA) is desaturated in the body to form arachidonic acid while parent omega-3 ...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2005-03-01 00:00:00
abstract::Auditory evoked responses using BERA were studied in 30 newborn babies with plasma bilirubin > or = 15 mgm/dl and repeated after treatment of neonatal jaundice with bilirubin levels of < or = 10 mgm/dl. A few jaundiced babies (16.5%) showed absent BERA response at the initial/subsequent examination. After treatment, 3...
journal_title:Indian journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02751203
更新日期:1993-05-01 00:00:00