Divergence in cis-regulatory networks: taking the 'species' out of cross-species analysis.

Abstract:

:Many essential transcription factors have conserved roles in regulating biological programs, yet their genomic occupancy can diverge significantly. A new study demonstrates that such variations are primarily due to cis-regulatory sequences, rather than differences between the regulators or nuclear environments.

journal_name

Genome Biol

journal_title

Genome biology

authors

Zinzen RP,Furlong EE

doi

10.1186/gb-2008-9-11-240

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

240

issue

11

eissn

1474-7596

issn

1474-760X

pii

gb-2008-9-11-240

journal_volume

9

pub_type

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